ABSTRACT
A case of rhabdomyosarcoma of the temporal bone in a six-year-old girl is reported. Updated literature and the main therapeutical approaches are reviewed.
Subject(s)
Rhabdomyosarcoma, Embryonal/therapy , Skull Neoplasms/therapy , Temporal Bone , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Child, Preschool , Combined Modality Therapy , Cyclophosphamide/therapeutic use , Dactinomycin/therapeutic use , Doxorubicin/therapeutic use , Etoposide/therapeutic use , Female , Follow-Up Studies , Humans , Ifosfamide/therapeutic use , Rhabdomyosarcoma, Embryonal/diagnostic imaging , Rhabdomyosarcoma, Embryonal/radiotherapy , Skull Neoplasms/diagnostic imaging , Skull Neoplasms/radiotherapy , Temporal Bone/diagnostic imaging , Time Factors , Tomography, X-Ray Computed , Vincristine/therapeutic useABSTRACT
We present an endometrial Müllerian adenosarcoma in which the sarcomatous component showed prominent nests of foamy cells that accounted for 50% of the neoplastic mesenchyma. Such foamy cells showed occasional cytological atypias and immunohistochemical features of histiocytic (macrophagic differentiation in the absence of changes that could substantiate the presence of an inflammatory infiltration of foamy histiocytes. These facts suggest histiocytic differentiation from neoplastic mesenchymal cells. Such differentiation has been reported in association with malignant mixed mesodermal tumor, but not in Müllerian adenosarcoma.
Subject(s)
Endometrial Neoplasms/pathology , Neoplasms, Germ Cell and Embryonal/pathology , Wilms Tumor/pathology , Biomarkers, Tumor , Female , Foam Cells/ultrastructure , Histiocytes/ultrastructure , Humans , Hysterectomy , Middle Aged , Ovariectomy , Salpingostomy , Treatment OutcomeABSTRACT
Two intracystic breast carcinomas with papillary pattern, one of which was argyrophilic, are reported, and their peculiar clinical features emphasized. The confusing terminology used in literature is also discussed. The fainly well-defined clinico-pathological features of these tumors allow them to be classed as a specific clinico-pathological variety of ductal breast carcinoma. The immunohistochemical study, which was negative to ALA, ACTH, GH, PRL and NSE, led us to consider the potential mucoid nature of the argyrophilic granules.
Subject(s)
Breast Neoplasms/pathology , Carcinoma, Papillary/pathology , Aged , Aged, 80 and over , Breast Neoplasms/surgery , Carcinoma, Papillary/surgery , Female , Humans , Immunohistochemistry , Lymph Node Excision , MastectomySubject(s)
Adenocarcinoma/pathology , Cysts/pathology , Kidney Neoplasms/pathology , Neoplasms, Multiple Primary , Aged , Humans , MaleABSTRACT
Se informan seis casos de enfermedad de Waldenstrom estudiados en el orden clínico y humoral, y se destaca la diversidad de formas clínicas presentes. Se hizo evidente la presencia de manifestaciones hemorrágicas e infecciones; esta última asociada frecuentemente a una inmunodeficiencia secundaria. Llama la atención la presentación de herpes zoster en dos enfermos. La anemia estuvo presente en la totalidad de los pacientes con una persistente elevación de las cifras de eritrosedimentación. Es fundamental el estudio inmunológico como complemento del estudio hematológico clásico. Todos los pacientes sobrepasaron la edad de 50 años (AU)
