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Rev Neurol ; 57(4): 145-9, 2013 Aug 16.
Article in Spanish | MEDLINE | ID: mdl-23884868

ABSTRACT

INTRODUCTION. Patients with chronic migraine often report lower cognitive performance, which affects their quality of life. AIMS. To analyse whether the mnemonic capacity of patients with chronic migraine is altered or not. SUBJECTS AND METHODS. A cross-sectional study was conducted in patients with chronic migraine evaluated consecutively in our unit, and paired by age (18-60 years) and gender with a control group consisting of cognitively healthy volunteers. The following cognitive instruments were administered: Folstein Minimental State Examination (MMSE), Memory Alteration Test (M@T), Montreal Cognitive Assessment (MoCA) and working memory. RESULTS. A total of 30 patients with chronic migraine were included (mean age: 49.33 ± 10.05 years) paired with a control group of 30 healthy volunteers (mean age: 44.83 ± 10.91 years). The mean elapsed time since onset of the patients with chronic migraine was 4.47 ± 2.74 years. On performing a comparative analysis between the two groups, significant differences were found with overall lower scores in the group of patients with chronic migraine in the MoCA (24.16 versus 29), M@T (43.76 versus 48.8) and working memory tests (17.5 versus 24.26). Performance in the MMSE was similar in both groups. CONCLUSIONS. Patients with chronic migraine can have lower cognitive performance regardless of distracting elements, such as pharmacological factors or psychiatric comorbidity, since chronic migraine can be understood as yet another element within the spectrum of chronic pain.


TITLE: Quejas mnesicas y migraña cronica.Introduccion. Los pacientes con migraña cronica refieren frecuentemente un menor rendimiento cognitivo, lo que interfiere en su calidad de vida. Objetivo. Analizar si existe alteracion en la capacidad mnesica de los pacientes con migraña cronica. Sujetos y metodos. Estudio transversal en pacientes con migraña cronica valorados de forma consecutiva en nuestra unidad, pareados en edad (18-60 años) y sexo con un grupo control constituido por voluntarios cognitivamente sanos. Se administraron los siguientes instrumentos cognitivos: test minimental de Folstein (MMSE), test de alteracion de memoria (T@M), evaluacion cognitiva de Montreal (MoCA) y memoria de trabajo. Resultados. Se incluyo un total de 30 pacientes con migraña cronica (edad media: 49,33 ± 10,05 años) pareados con un grupo control de 30 voluntarios sanos (edad media: 44,83 ± 10,91 años). El tiempo medio de evolucion de los pacientes con migraña cronica fue de 4,47 ± 2,74 años. Al realizar el analisis comparativo entre ambos grupos, se encontraron diferencias significativas con puntuaciones mas bajas de forma global en el grupo de pacientes con migraña cronica en el test de MoCA (24,16 frente a 29), T@M (43,76 frente a 48,8) y memoria de trabajo (17,5 frente a 24,26). El rendimiento en el MMSE fue similar en ambos grupos. Conclusiones. Los pacientes con migraña cronica pueden tener un menor rendimiento cognitivo independientemente de elementos distractores, como el farmacologico o la comorbilidad psiquiatrica, dado que la migraña cronica puede entenderse como un elemento mas dentro del espectro del dolor cronico.


Subject(s)
Memory Disorders/etiology , Migraine Disorders/psychology , Adolescent , Adult , Case-Control Studies , Chronic Disease , Chronic Pain/psychology , Cross-Sectional Studies , Educational Status , Female , Headache Disorders, Secondary/psychology , Humans , Male , Middle Aged , Neuropsychological Tests , Psychological Tests , Young Adult
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