ABSTRACT
Time course of burn wound healing was studied in 32 patients with severe thermal trauma during tube hyperalimentation (TH). Similar study was conducted in 20 patients of the control group who did not receive TH. Early inclusion of TH in the complex of therapeutic measures stimulated some of the links of burn wound histogenesis: the formation of the demarcation swelling and rejection of the necrotic tissue occurred sooner, the leucocytic-macrophagal reaction was activated, and granulation and epithelialization processes were intensified. Thus, the use of the TH method in patients with burns makes it possible to conduct active surgical tactics for restoration of the lost skin area successfully as a result of which they recover within a shorter time than the patients of the control group.
Subject(s)
Burns/surgery , Enteral Nutrition , Parenteral Nutrition, Total , Wound Healing/physiology , Burns/physiopathology , Critical Care , Humans , Preoperative Care , Skin Transplantation/methodsABSTRACT
High caloric probe hyperalimentation used in 37 burned patients in addition to routine ration resulted in normalization of metabolic processes due to the inhibition of biopolymer degradation and stabilization of biological membranes followed by the activation of anabolic processes.
Subject(s)
Burns/therapy , Enteral Nutrition , Parenteral Nutrition, Total , Protein-Energy Malnutrition/therapy , Body Surface Area , Burns/metabolism , Humans , Protein-Energy Malnutrition/etiologySubject(s)
Burns/therapy , Enteral Nutrition , Parenteral Nutrition, Total , Adolescent , Adult , Food, Formulated , Humans , Middle AgedABSTRACT
The KEP-1 system is designed for tube hyperalimentation of patients, including burn patients. It consists of a four-channel peristaltic pump and a liquid food mixer tank. The results of clinical testing are given.
Subject(s)
Enteral Nutrition/instrumentation , Burns/therapy , HumansSubject(s)
Burns/therapy , Enteral Nutrition , Adolescent , Adult , Burns/metabolism , Humans , Intestinal Absorption , Middle Aged , Nutritional Physiological PhenomenaSubject(s)
Burns/therapy , Enteral Nutrition , Basal Metabolism , Body Weight , Burns/metabolism , Energy Intake , Energy Metabolism , Female , Humans , Leukocyte Count , Male , Nursing Records , Nutritional RequirementsABSTRACT
Protein assimilation was studied by means of radionuclide diagnosis methods, using 131I-albumin, in 10 patients with grave burns, fed a high-caloric dosed diet via a gastric tube (HCDGT). Simultaneously, the intestinal absorption was studied by the alpha-xylose test, and some protein metabolism parameters were investigated. The level of protein assimilation in burned patients was found to fluctuate within a wide range and to be most often reduced. A direct relationship was observed between protein assimilation and small intestine absorption. The degree of protein assimilation influenced the time course of protein metabolism: in all the examined patients on HCDGT a positive tendency of the anabolic processes was observed.
Subject(s)
Burns/metabolism , Dietary Proteins/metabolism , Enteral Nutrition , Adult , Burns/diet therapy , Humans , Intestinal Absorption , Intestine, Small/metabolism , Middle AgedSubject(s)
Burns/therapy , Enteral Nutrition , Fatty Acids, Nonesterified/blood , Acute Disease , Adolescent , Adult , Burns/blood , Chromatography, Gas , Female , Humans , Lipids/blood , Male , Middle Aged , Time FactorsABSTRACT
The blood corticosteroid levels of patients with severe burns were studied at different periods of the disease (burn shock, acute burn toxemia, septicotoxemia). The mean daily blood corticosteroid content in the burnt patients was increased. The most pronounced corticosteroid concentration increase (112.6 +/- 21.7 micrograms %) was seen in patients during burn shock. In toxemia and initial septicotoxemia, the corticosteroid concentration slightly decreased (41.7 +/- 7.1 and 49.4 +/- 5.4 micrograms %, respectively). The blood corticosteroid level abruptly fell to the lower limits of normal in patients during septicotoxemia, complicated with burn exhaustion. Deviations in the blood corticosteroid concentration of the burnt patients within 24 hours significantly differed from the normal circadian rhythm of the blood hormone release.