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1.
Arch Esp Urol ; 66(2): 237-41, 2013 Mar.
Article in English, Spanish | MEDLINE | ID: mdl-23589603

ABSTRACT

OBJECTIVE: Malacoplakia is a rare chronic granulomatous disorder that mostly affects the urogenital system. This article describes a case of uncommon location of this disease at the level of the seminal vesicles and the clinical, imaging and histological particularities of this medical entity. METHOD: We report the case of a 69 year-old male consulting for constitutional syndrome that presented a pelvic tumor on the image studies, possibly arising in the seminal vesicles. RESULTS: The diagnosis was made after performing transrectal ultrasound and seminal vesicles biopsy by the pathognomonic histological findings of Michaelis Gutmann bodies. The presence of E. Coli in urine culture in our patient justified the use of a long-term antibiotic therapy such as quinolones with very good results. CONCLUSION: Malacoplakia of the seminal vesicles is an extremely rare condition, sometimes with non-specific clinical presentation. Its diagnosis is histological and it has good response to prolonged antibiotic therapy with a benign outcome.


Subject(s)
Malacoplakia/pathology , Seminal Vesicles/pathology , Aged , Antigens, CD/analysis , Antigens, Differentiation, Myelomonocytic/analysis , Biopsy , Cytoplasmic Granules/pathology , Humans , Immunohistochemistry , Malacoplakia/diagnostic imaging , Male , Seminal Vesicles/surgery , Tomography, X-Ray Computed , Ultrasonography
2.
Arch. esp. urol. (Ed. impr.) ; 66(2): 237-241, mar. 2013. ilus
Article in Spanish | IBECS | ID: ibc-110057

ABSTRACT

OBJETIVO: La malacoplaquia es un proceso inflamatorio granulomatoso crónico poco frecuente siendo el aparato genitourinario el asiento más frecuente de esta enfermedad. Se describe un caso que afecta a vesículas seminales con sus particularidades clínicas, diagnósticas e histológicas de esta entidad. MÉTODO: Varón, de 69 años ingresado en otro servicio por síndrome constitucional que tras la realización de pruebas de imagen (tomografía computerizada) se detecta una masa pélvica de posible origen en vesículas seminales. RESULTADOS: Se realiza ecografía transrectal y biopsia de vesículas seminales que en el estudio histológico evidencian la presencia de cuerpos de Michaelis Gutmann patognomónicos de malacoplaquia. El urocultivo fue positivo a Escherichia Coli, infección frecuentemente asociada a esta enfermedad y cuyo tratamiento de elección es la antibioterapia a largo plazo con fluoroquinolonas, que consiguió buenos resultados en nuestro caso. CONCLUSIÓN: La malacoplaquia localizada en vesículas seminales es una entidad extremadamente rara, con clínica a veces inespecífica, de diagnóstico histológico y tratamiento médico antibiótico con una evolución benigna(AU)


OBJECTIVE: Malacoplakia is a rare chronic granulomatous disorder that mostly affects the urogenital system. This article describes a case of uncommon location of this disease at the level of the seminal vesicles and the clinical, imaging and histological particularities of this medical entity. METHOD: We report the case of a 69 year-old male consulting for constitutional syndrome that presented a pelvic tumor on the image studies, possibly arising in the seminal vesicles. RESULTS: The diagnosis was made after performing transrectal ultrasound and seminal vesicles biopsy by the pathognomonic histological findings of Michaelis Gutmann bodies. The presence of E. Coli in urine culture in our patient justified the use of a long-term antibiotic therapy such as quinolones with very good results. CONCLUSION: Malacoplakia of the seminal vesicles is an extremely rare condition, sometimes with non-specific clinical presentation. Its diagnosis is histological and it has good response to prolonged antibiotic therapy with a benign outcome(AU)


Subject(s)
Humans , Male , Aged , Malacoplakia/diagnosis , Seminal Vesicles/microbiology , Anti-Bacterial Agents/therapeutic use , Escherichia coli/pathogenicity , Escherichia coli Infections/complications , Risk Factors
3.
Rev. esp. patol ; 43(1): 52-54, ene.-mar. 2010. ilus
Article in Spanish | IBECS | ID: ibc-79249

ABSTRACT

Uterine mucinosis and vasculitis associated with lupus erythematous(AU)


The association of cutaneous papulonodular mucinosis with lupus erythematosus has long been recognized. Massive cutaneous deposits of mucin and periorbital mucinosis have also been reported in patients with lupus. Recently, a report was published of two cases of mucin deposits in the myometrium of patients with lupus, denominated "myxoidosis" by the authors. A case is presented of vasculitis and diffuse, predominately myometrial, mucinosis, in the uterus of a patient with lupus erythematosus. The term "mucinosis" and not "myxoidosis" is recommended, even when referring to the uterus, in order to unify the terminology of pathological findings that have similar histological and histochemical features to the cutaneous lesions found in lupus erythematosus(AU)


Subject(s)
Humans , Female , Adult , Lupus Erythematosus, Systemic/complications , Lupus Erythematosus, Systemic/diagnosis , Mucinoses/complications , Mucinoses/diagnosis , Vasculitis/complications , Vasculitis/diagnosis , Hysterectomy/methods , Hysterectomy/trends , Cervix Uteri/anatomy & histology , Cervix Uteri/pathology , Uterine Neoplasms/pathology , Uterine Neoplasms/ultrastructure , Uterus/anatomy & histology , Uterus/pathology
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