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Am Heart J ; 178: 151-60, 2016 08.
Article in English | MEDLINE | ID: mdl-27502863

ABSTRACT

BACKGROUND: This study aimed to evaluate the clinical and epidemiologic profile of congestive heart failure at the principal free-care hospital in Haiti. Cardiovascular disease represents the most prevalent cause of admissions to the medical service of the University Hospital of the State of Haiti. No previous study has examined the demographics of congestive heart failure in urban Haiti. METHODS: Two hundred forty-seven patients presented to the inpatient service between May 2011 and May 2013. Evaluation included history and physical, CBC, renal/metabolic profile, serum glucose, anti-HIV antibody, ECG, chest radiograph and echocardiogram. Treatment included angiotensin converting enzyme inhibitors, furosemide and spironolactone, carvedilol, digoxin and anticoagulation. RESULTS: Women (62.4%) outnumbered men; patients were relatively young (mean age 50.1) and from the lowest socio-economic levels of the population. Nearly all (98.8%) presented with NYHA III-IV status, with correspondingly high mortality (23.3%). Echocardiography showed 73% dilated cardiomyopathy; 83% showed moderate to severe LV systolic dysfunction (mean EF 36.5 +/- 15%) and 17% preserved LV systolic function. The three principal etiologies were dilated cardiomyopathy (29%) hypertensive cardiomyopathy (27%) and peripartum cardiomyopathy (20%). Ischemic cardiomyopathy was rare (3.4%). At 27 months follow-up, 76.7% of the patients were alive and well. Among those who died, mean survival time was 113 days. Readmission carried a poor prognosis. CONCLUSIONS: This congestive heart failure study from Haiti shows an unusually high proportion of young women, primarily due to peripartum cardiomyopathy. Ischemic cardiomyopathy is rare, as in Africa. Further study is warranted to address the particular problem of the high frequency of peripartum cardiomyopathy in this population.


Subject(s)
Cardiomyopathy, Dilated/diagnostic imaging , Heart Failure/diagnostic imaging , Pregnancy Complications, Cardiovascular/diagnostic imaging , Puerperal Disorders/diagnostic imaging , Adolescent , Adrenergic beta-Antagonists/therapeutic use , Adult , Age Distribution , Aged , Aged, 80 and over , Angiotensin-Converting Enzyme Inhibitors/therapeutic use , Anticoagulants/therapeutic use , Carbazoles/therapeutic use , Cardiomyopathy, Dilated/drug therapy , Cardiomyopathy, Dilated/epidemiology , Cardiomyopathy, Dilated/physiopathology , Cardiotonic Agents/therapeutic use , Carvedilol , Cohort Studies , Digoxin/therapeutic use , Diuretics/therapeutic use , Echocardiography , Electrocardiography , Female , Furosemide/therapeutic use , Haiti , Heart Failure/drug therapy , Heart Failure/epidemiology , Heart Failure/physiopathology , Hospitalization , Hospitals, University , Hospitals, Urban , Humans , Hypertension/epidemiology , Male , Middle Aged , Pregnancy , Pregnancy Complications, Cardiovascular/drug therapy , Pregnancy Complications, Cardiovascular/epidemiology , Pregnancy Complications, Cardiovascular/physiopathology , Propanolamines/therapeutic use , Prospective Studies , Puerperal Disorders/drug therapy , Puerperal Disorders/epidemiology , Puerperal Disorders/physiopathology , Sex Distribution , Spironolactone/therapeutic use , Stroke Volume , Young Adult
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