Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 7 de 7
Filter
Add more filters










Database
Language
Publication year range
1.
Rev Sci Instrum ; 83(10): 10D511, 2012 Oct.
Article in English | MEDLINE | ID: mdl-23130790

ABSTRACT

A new endoscope with optimised divertor view has been developed in order to survey and monitor the emission of specific impurities such as tungsten and the remaining carbon as well as beryllium in the tungsten divertor of JET after the implementation of the ITER-like wall in 2011. The endoscope is a prototype for testing an ITER relevant design concept based on reflective optics only. It may be subject to high neutron fluxes as expected in ITER. The operating wavelength range, from 390 nm to 2500 nm, allows the measurements of the emission of all expected impurities (W I, Be II, C I, C II, C III) with high optical transmittance (≥ 30% in the designed wavelength range) as well as high spatial resolution that is ≤ 2 mm at the object plane and ≤ 3 mm for the full depth of field (± 0.7 m). The new optical design includes options for in situ calibration of the endoscope transmittance during the experimental campaign, which allows the continuous tracing of possible transmittance degradation with time due to impurity deposition and erosion by fast neutral particles. In parallel to the new optical design, a new type of possibly ITER relevant shutter system based on pneumatic techniques has been developed and integrated into the endoscope head. The endoscope is equipped with four digital CCD cameras, each combined with two filter wheels for narrow band interference and neutral density filters. Additionally, two protection cameras in the λ > 0.95 µm range have been integrated in the optical design for the real time wall protection during the plasma operation of JET.

2.
Rev Sci Instrum ; 83(10): 10D517, 2012 Oct.
Article in English | MEDLINE | ID: mdl-23130791

ABSTRACT

In preparation for ITER, JET has been upgraded with a new ITER-like wall (ILW), whereby the main plasma facing components, previously of carbon, have been replaced by mainly Be in the main chamber and W in the divertor. As part of the many diagnostic enhancements, a new, survey, visible spectroscopy diagnostic has been installed for the characterization of the ILW. An array of eight lines-of-sight (LOS) view radially one of the two JET neutral beam shine through areas (W coated carbon fibre composite tiles) at the inner wall. In addition, one vertical LOS views the solid W tile at the outer divertor. The light emitted from the plasma is coupled to a series of compact overview spectrometers, with overall wavelength range of 380-960 nm and to one high resolution Echelle overview spectrometer covering the wavelength range 365-720 nm. The new survey diagnostic has been absolutely calibrated in situ by means of a radiometric light source placed inside the JET vessel in front of the whole optical path and operated by remote handling. The diagnostic is operated in every JET discharge, routinely monitoring photon fluxes from intrinsic and extrinsic impurities (e.g., Be, C, W, N, and Ne), molecules (e.g., BeD, D(2), ND) and main chamber and divertor recycling (typically Dα, Dß, and Dγ). The paper presents a technical description of the diagnostic and first measurements during JET discharges.

3.
Rev Sci Instrum ; 83(10): 10D530, 2012 Oct.
Article in English | MEDLINE | ID: mdl-23130793

ABSTRACT

For the new ITER-like wall at JET, two new infrared diagnostics (KL9B, KL3B) have been installed. These diagnostics can operate between 3.5 and 5 µm and up to sampling frequencies of ∼20 kHz. KL9B and KL3B image the horizontal and vertical tiles of the divertor. The divertor tiles are tungsten coated carbon fiber composite except the central tile which is bulk tungsten and consists of lamella segments. The thermal emission between lamellae affects the surface temperature measurement and therefore KL9A has been upgraded to achieve a higher spatial resolution (by a factor of 2). A technical description of KL9A, KL9B, and KL3B and cross correlation with a near infrared camera and a two-color pyrometer is presented.

4.
Antimicrob Agents Chemother ; 22(4): 648-51, 1982 Oct.
Article in English | MEDLINE | ID: mdl-6758688

ABSTRACT

Radioimmunoassay and enzyme immunoassay methods for analysis of serum gentamicin levels have been shown to be comparable. The purpose of this study was to determine if serum concentration-time data from the same patient assayed by radioimmunoassay and enzyme immunoassay would provide the same estimates for half-life, elimination rate constant, distribution volume, drug clearance, and gentamicin dose. A total of 103 pre- and postinfusion serum samples were obtained from 32 patients. The samples were divided and assayed by radioimmunoassay and enzyme immunoassay. Serum concentration-time data were fitted to a one-compartment model, and kinetic calculations were performed using the method of Sawchuk et al. (Clin. Pharmacol. Ther. 21:362-369, 1977). While good correlation was established between the two assay methods, significant (P less than 0.05) mean differences were seen in distribution volume (25%), gentamicin clearance (15%), and half-life (11%), using the quantitative data from both methods. Because of differences noted in these pharmacokinetic parameters, significant differences were also noted in dosage calculations. We conclude that there are differences in the pharmacokinetic parameters obtained using results from the radioimmunoassay and enzyme immunoassay. These differences also translate into significant differences between dosage recommendations when individualization of the gentamicin regimen is attempted.


Subject(s)
Gentamicins/blood , Adolescent , Adult , Aged , Female , Gentamicins/administration & dosage , Half-Life , Humans , Immunoenzyme Techniques , Kinetics , Male , Middle Aged , Radioimmunoassay/methods
SELECTION OF CITATIONS
SEARCH DETAIL
...