ABSTRACT
During the nineties it was described, as an original finding, the existence of afferent amyelinic nerve endings in animal dorsal root ganglia (DRG) caused by diverse experimental lesions. These works do not take into account the historical studies carried out by Ehrlich (1886), Ramón y Cajal (1890) and Dogiel (1885) among others. Ramón y Cajal (1899) confirmed the existence of these nerve endings naming them after their discoverer as "Dogiel's arborisations". Ramón y Cajal claims that these endings originate from fibres of sympathetic nature, something supported by later authors devoted to this topic. In any case, the same authors remarked already a possible relationship with pathological phenomena, nonetheless always referring to the frequent occasions in which the same images appeared in healthy animals. In this work we review the bibliography about the classically named "Terminal Dogiel's nests" which in modern literature have been referred to as sprouting of sympathetic axons in dorsal root ganglia likely related with sympathetically maintained pain. Furthermore, we present the finding, not described up to date, of multiple afferent amyelinic nervous endings related with the "Terminal Dogiel's nests" observed in different DRG from young adult healthy rabbits.
Subject(s)
Ganglia, Spinal/cytology , Sympathetic Nervous System/cytology , Animals , Dendrites/physiology , Humans , Nerve Growth Factors/physiology , Norepinephrine/physiology , Peripheral Nerve InjuriesABSTRACT
The duct system of murine submandibular gland is composed, in contrast with other mammals, by four types of ducts, among which the granular duct is unique for rodents. The granular duct shows a typical secretory structure with a clear intersex morphological diversity on which we carried out a morphometrical study in order to determine the relative area of each duct in rats in comparison with the rest of ducts and the whole gland. Our results, in both sexes, show that the duct with the broadest surface is the granular duct, followed by the excretory, striated and the intercalated ducts. In addition, we found a significant intersex difference between the relative surface of the granular and the excretory ducts, being bigger in males than in females. Finally, in both sexes, there is a greater variation in the data related to the excretory ducts than to the other ducts.
Subject(s)
Submandibular Gland/metabolism , Submandibular Gland/pathology , Animals , Female , Male , Rats , Rats, Wistar , Sex Factors , SoftwareABSTRACT
Objetivos: La cirugía conservadora del miembro en los sarcomas óseos distales a la rodilla presenta muchas dificultades debido en especial a la poca cobertura muscular, por lo que la amputación es la técnica más utilizada.Material y métodos: Se expone la experiencia del servicio entre junio de 1990 y septiembre de 1998: 7 pacientes con sarcomas óseos primarios en dicha localización (cinco en la tibia y 2 en el peroné) a los que se les realizó una cirugía conservadora del miembro. El diagnóstico histopatológico fue: 5 osteosarcomas, un fibrohistiocitoma maligno y un tumor neuroectodérmico primitivo periférico. La reconstrucción se realizó en 5 casos con aloinjerto estructural de banco, y a otro con peroné proximal; un paciente no requirió reconstrucción.Resultados: Utilizando las escalas del Instituto Rizzoli o la de Mankin, se obtuvieron resultados buenos o excelentes en 4 pacientes y regulares o malos en 3. Las complicaciones fueron: una recidiva local, una infección profunda y una pseudoartrosis.Conclusión: Con una adecuada selección es posible realizar cirugía conservadora del miembro en sarcomas óseos que presenten esta localización (AU)
Subject(s)
Adolescent , Adult , Female , Male , Child , Humans , Sarcoma/surgery , Knee Joint/surgery , Bone Neoplasms/surgery , Tibia/pathology , Surgical Flaps , Fibula/pathology , Bone Neoplasms/drug therapyABSTRACT
Se revisa la indicación del enclavado endomedular cerrojado tipo Seidel en las fracturas metastásicas del húmero, estudiando una serie de 16 casos en las que el clavo se colocó a cielo cerrado y en otros dos se realizó una apertura del foco con aporte de injerto. Se hace referencia a 3 casos en que el clavo sirvió de soporte a un aloinjerto estructural proximal de húmero empleado para sustituir una lesión epifiso-metafisaria proximal. El tumor original más frecuente fue el carcinoma de mama en siete casos. La supervivencia media fue de 9,7 meses, consolidaron 10 casos en un tiempo medio de seis semanas. En dos casos hubo una parálisis radial postoperatoria transitoria y dos presentaron una progresión de la lesión. No hubo infecciones. El resto tuvo una buena evolución clínica (AU)
Subject(s)
Humeral Fractures , Fractures, Spontaneous , Bone NailsABSTRACT
Thirty-five fractures of the distal femur were treated by antegrade intramedullary nailing. All of the fractures were treated by a closed technique. In the cases in which there was extension of the fracture to the knee joint, the fracture initially was stabilized with percutaneous lag screws. Four patients died before fracture healing was complete and 11 were lost to followup. There were 14 extraarticular (Type A) and six intraarticular (Type C1 and Type C2) fractures. All of these fractures healed in a mean time of 17.27 weeks. Functional outcome using the Hospital for Special Surgery knee score was 87. Complications were infrequent with one (5%) pseudarthrosis and no infections. Although this is a very demanding technique, antegrade intramedullary nailing is an efficient procedure compared with other methods of open reduction and internal fixation for difficult distal femoral fractures.
