ABSTRACT
Mucornycosis is a rare fungal infection most commonly occuring in patients with severe immunocompromise, diabetes, uremia or trauma. Only a few cases of non axial skeletal bone osteomyelitis have been reported. We report a case of nosocomial cellulitis and osteomyelitis complicating a posttraumatic bacterial infection, successfully treated with liposomial amphotericin B and surgical debridement. Traumatized patients with extensive tissue loss, receiving broad-spectrum antibiotics, can develop impaired immune responses and are at risk for fungal infections.
ABSTRACT
We describe a fatal case of haemolytic uraemic syndrome in a young woman with AIDS, and disseminated adenovirus (ADV) and cytomegalovirus (CMV) co-infection. We hypothesize that ADV/CMV co-infection may have a causative role in this clinical picture.
Subject(s)
Acquired Immunodeficiency Syndrome/complications , Adenovirus Infections, Human/complications , Cytomegalovirus Infections/complications , Hemolytic-Uremic Syndrome/etiology , Acute Kidney Injury/etiology , Adenovirus Infections, Human/drug therapy , Colitis/etiology , Colitis/virology , Cytomegalovirus Infections/drug therapy , Enteritis/etiology , Enteritis/virology , Fatal Outcome , Female , Foscarnet/therapeutic use , Ganciclovir/therapeutic use , Humans , Respiratory Distress Syndrome/etiology , Trimethoprim, Sulfamethoxazole Drug Combination/therapeutic useABSTRACT
Infection of the central nervous system due to Listeria monocytogenes is uncommon. The treatment of choice is ampicillin. We describe in this report a case of rhombencephalitis caused by Listeria monocytogenes successfully treated with linezolid. To the best of our knowledge, this is the first case in which linezolid was used to treat infection of the central nervous system caused by this organism.
Subject(s)
Acetamides/therapeutic use , Anti-Bacterial Agents/therapeutic use , Encephalitis/drug therapy , Encephalitis/microbiology , Listeriosis/drug therapy , Oxazolidinones/therapeutic use , Humans , Linezolid , Male , Middle AgedABSTRACT
To evaluate, for the first time, circulation and clinical expression of Toscana virus (ToSv) in Umbria region we studied: (1) 93 cases of aseptic meningitis and meningoencephalitis admitted to our Department from 1989 to 2001 with negative results for common neurotropic virus; (2) 50 healthy subjects. Specific antibodies (IgM and IgG) anti-TOSv were found in 36.6% of aseptic meningitis, in 6.06% of meningoencephalitis and (IgG) in 16% of healthy subjects.
Subject(s)
Meningitis/blood , Sandfly fever Naples virus/pathogenicity , Adolescent , Adult , Aged , Cohort Studies , Enzyme-Linked Immunosorbent Assay , Female , Humans , Immunoglobulin G/blood , Immunoglobulin G/immunology , Immunoglobulin M/blood , Immunoglobulin M/immunology , Italy/epidemiology , Male , Meningitis/epidemiology , Meningitis/virology , Meningoencephalitis/blood , Meningoencephalitis/epidemiology , Meningoencephalitis/virology , Middle Aged , Sandfly fever Naples virus/immunology , Sandfly fever Naples virus/isolation & purification , Seroepidemiologic StudiesABSTRACT
A novel cavity design based on a confocal negative branch unstable resonator configuration is presented. A proper choice for the size of the field limiting aperture, set at the common focal plane of the mirrors, results in removal of the hot spot inside the cavity and in the smoothing of the spatial profile of the oscillating mode. Application of this scheme to a pulsed Nd:YAG oscillator is thoroughly characterized in a variety of operational modes (fixed-Q, Q-switching, mode-locking). The main results are a high efficiency of energy extraction and excellent phase and amplitude profiles of the output beam, which shows real transform-limited performances.
