[Mechanism of action of an exopolysaccharide from Mycobacterium cyaneum on the local cellular reaction in experimental coli infection]. / K mekhanizmu deistviia ékzopolisakharida Mycobacterium cyaneum na mestnuiu kletochnuiu reaktsiiu pri éksperimental'noi koli-infektsii.

A study was made of the effect of the exopolysaccharide (PS) M. cyaneum B-646 on cellular reaction in peritoneal exudate of white mice infected with E. coli. PS intensified the migration of phagocytic cells to the focus of infection, accelerated neutrophil maturation, promoted an earlier and more active involvement of neutrophils, particularly of macrophages, into the phagocytic process. In this case, there was a marked correlation between the magnitude of phagocyte population (of macrophage population to a greater degree) in peritoneal exudate and absorption capacity. PS activated macrophagal lysosomes, affecting selectively the accumulation of enzymes by the cells and lysosomal membrane permeability. The action of PS is dose-dependent. Under experimental conditions in question, the most favourable effect on local cellular reaction was exerted by PS in a dose of 20 micrograms per mouse.

[Spectral-correlation analysis of high-frequency EEG components of the rabbit cerebral cortex during orienting and defensive responses]. / Spektral'no-korreliatsionnyi analiz vysokochastotnykh sostavliaiushchikh EEG kory golovnogo mozga krolika pri orientirovochnoi i oboronitel'noi reaktsiiakh.

A change was shown in the EEG power spectra of the sensorimotor, visual and auditory neocortical areas and the dorsal hippocampus, and corresponding coherence functions in the range of 14.6-110 c/s during an orienting reaction and the formation of a defensive conditioned reflex in rabbits. It was suggested that the rhythm of about 5 c/s appearing during formation of the conditioned reflex, serves for the functional integration of the brain structures which is specific for a certain functional state.

[Correlation between bioelectrical processes of the cortex, thalamus, midbrain reticular formation during formation of a defensive conditioned reflex in rabbits]. / Sootnoshenie mezhdu bioélektricheskimi protsessami kory, talamusa i retikuliarnoi formatsii srednego mozga pri formirovanii oboronitel'nogo uslovnogo refleksa u krolika.

EEG power spectra of the sensorimotor area of the neocortex, the dorsal hippocampus, midbrain reticular formation and anteroventral thalamic nucleus, as well as corresponding coherence functions and phase spectra, undergo changes during formation and performance of defensive conditioned reflex in rabbit. The conclusion is draen that in the process of conditioning a morphofunctional system of brain structures is established including the above mentioned formations. Their functional integration occurs on the basis of theta-rhythm. The execution of a conditioned act requires isorhythmicity of electrical processes within the theta-range in the studied structures and an adequate level of their excitability, which is manifested in the dominance of 6,0 c/s frequency.