[Effect of a monoamine oxidase inhibitor on the level of seizure readiness and functional asymmetry of the brain]. / Vliianie ingibitora monoaminoksidazy na uroven' sudorozhnoi gotovnosti i funktsional'nuiu asimmetriiu mozga.

The state of seizures readiness in epileptic rats of Krushinsky--Molodkina line is characterised by interhemispheric synchroneity, revealed with electrophysiological methods parallely with the study of the catecholamine content in the brain tissue. On the contrary in animals insensitive to epileptogenic stimulus, considerable manifestations of the functional interhemispheric asymmetry were recorded. The monoaminoxidase inhibitor iprazide increasing the adrenaline and noradrenaline content in the brain and causing their uneven distribution between the hemispheres, leads to a sharp decline in the level of seizures readiness, which is accompanied by the appearance of bioelectrical and catecholamine asymmetry comparable with that in the animals resistent to the epileptogenic stimulus.

[Primary response mechanisms of the adrenal cortex in dogs to pain stress]. / O mekhanizmakh pervichnogo otveta kory nadpochechnikov sobak na bolevoi stress.

The adrenal cortex of dogs shows a drop in the glucocorticoid content 10--15 sec after the pain action in the presence of the free cholesterol level increase and its esterified form drop. The concentrations of hormones in the blood falls chiefly at the expense of protein bound hydrocortisone. The subsequent phase of the reaction (after 30--60 sec) is characterized by a considerable accumulation of the hormones by the gland. The level of free glucocorticoids significantly increases, the initial ratio of hydrocortisone and cortisone restores, and transcortin depot is filled up. The role of the adrenal and transcortine depot in realization of feedback mechanisms under stress is discussed.