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Mater Sci Eng C Mater Biol Appl ; 61: 875-8, 2016 Apr 01.
Article in English | MEDLINE | ID: mdl-26838919

ABSTRACT

A carbonated hydrocalumite was synthesized by the microwave method for being used as antacid. The gel was formed using Ca and Al nitrate solutions in a basic medium (NaOH+Na2CO3), then, this gel was aged and heated in a domestic microwave for 2.5 min (1250 W). The obtained white solid was washed with distilled water, dried in an oven at 100 °C for 18 h and characterized by different techniques such as: X-ray diffraction (XRD), Fourier transformed infrared spectroscopy (FT-IR), BET surface area measurements, scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDX). Finally, the carbonated hydrocalumite was tested as antacid by using a synthetic gastric juice and its activity was compared with a commercial antacid formulated with hydrotalcite. Results showed that the carbonated hydrocalumite was more effective than that commercial antacid.


Subject(s)
Antacids/chemical synthesis , Microwaves , Aluminum Compounds/chemistry , Antacids/chemistry , Calcium Compounds/chemistry , Carbonates/chemistry , Gels/chemical synthesis , Gels/chemistry , Microscopy, Electron, Scanning , Nitrates/chemistry , Spectrometry, X-Ray Emission , Spectroscopy, Fourier Transform Infrared , X-Ray Diffraction
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