ABSTRACT
The study was undertaken to determine the serum lipid profile in patients with obstructive jaundice (OJ) of various genesis versus those with chronic viral hepatitis B (CVHB). The serum lipid profile was studied in 50 patients with OJ whose cause was cancer diseases and calculous cholecystitis in 20 and 30 patients, respectively. Thirty patients with CVHB were examined as a control group. In patients with OJ, the relative serum content of phospholipids was found to be twice less than that in patients with CVHB. In patients with OJ, hyperlipemia was mainly caused by free cholesterol or cholesterol esters. As compared with the patients with calculous cholecystitis and CVHB, the patients with cancer diseases had low sphingomyelin levels; this fact may be used as an additional measure in detecting OJ of cancer genesis.
