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1.
Andes Pediatr ; 95(1): 69-76, 2024 Feb.
Article in Spanish | MEDLINE | ID: mdl-38587346

ABSTRACT

In adolescence and especially in females, greater body dissatisfaction has been evidenced, which is defined as a negative evaluation of one's own body, being a strong predictor of eating disorders and obesity. OBJECTIVE: To relate body dissatisfaction with self-esteem, depression, and body mass index in adolescents. SUBJECTS AND METHOD: Quantitative, correlational, and cross-sectional study in a sample of 397 school adolescents (180 males and 217 females) from Concepción, Chile, aged 10 to 19 years, to whom the following instruments were applied: Body Shape Questionnaire (BSQ) to assess body dissatisfaction, Rosenberg Self-Esteem Scale, Beck's Depression Inventory-II for those older than 14 years, and Birleson Depression Self-Rating Scale for those younger than 14 years. Body mass index z-score was determined. Spearman's correlation coefficient was estimated for all variables. RESULTS: Body dissatisfaction was reported in 54.9 % of females and 18.3 % of males. Body dissatisfaction was positively correlated with age, z-BMI, and depression (p < 0.01) and negatively correlated with self-esteem (p < 0.01). When body dissatisfaction was differentiated by sex, the same significant correlations remained, except for age. CONCLUSIONS: The results confirm the relationship between body dissatisfaction with self-esteem, depression, and BMI. The importance of promoting healthy self-esteem and body image from an early age to prevent eating disorders and obesity is emphasized.


Subject(s)
Body Dissatisfaction , Nutritional Status , Male , Female , Adolescent , Humans , Depression/diagnosis , Cross-Sectional Studies , Obesity
2.
Adv Exp Med Biol ; 1428: 127-148, 2023.
Article in English | MEDLINE | ID: mdl-37466772

ABSTRACT

In preeclampsia, the shallow invasion of cytotrophoblast cells to uterine spiral arteries, leading to a reduction in placental blood flow, is associated with an imbalance of proangiogenic/antiangiogenic factors to impaired nitric oxide (NO) production. Proangiogenic factors, such as vascular endothelial growth factor (VEGF) and placental growth factor (PlGF), require NO to induce angiogenesis through antioxidant regulation mechanisms. At the same time, there are increases in antiangiogenic factors in preeclampsia, such as soluble fms-like tyrosine kinase type 1 receptor (sFIt1) and toll-like receptor 9 (TLR9), which are mechanism derivates in the reduction of NO bioavailability and oxidative stress in placenta.Different strategies have been proposed to prevent or alleviate the detrimental effects of preeclampsia. However, the only intervention to avoid the severe consequences of the disease is the interruption of pregnancy. In this scenario, different approaches have been analysed to treat preeclamptic pregnant women safely. The supplementation with amino acids is one of them, especially those associated with NO synthesis. In this review, we discuss emerging concepts in the pathogenesis of preeclampsia to highlight L-arginine and L-citrulline supplementation as potential strategies to improve birth outcomes. Clinical and experimental data concerning L-arginine and L-citrulline supplementation have shown benefits in improving NO availability in the placenta and uterine-placental circulation, prolonging pregnancy in patients with gestational hypertension and decreasing maternal blood pressure.


Subject(s)
Pre-Eclampsia , Female , Pregnancy , Humans , Pre-Eclampsia/drug therapy , Pre-Eclampsia/metabolism , Placenta/metabolism , Citrulline/therapeutic use , Citrulline/metabolism , Citrulline/pharmacology , Arginine/metabolism , Vascular Endothelial Growth Factor A/metabolism , Placenta Growth Factor/metabolism , Placenta Growth Factor/pharmacology , Dietary Supplements , Vascular Endothelial Growth Factor Receptor-1/metabolism
3.
Rev. chil. nutr ; 46(6): 727-734, dic. 2019. tab, graf
Article in Spanish | LILACS | ID: biblio-1058135

ABSTRACT

Objetivo: Identificar las creencias conductuales, normativas y de control que subyacen a la alimentación saludable en estudiantes de la Universidad de Guadalajara, México. Método: Estudio cualitativo y exploratorio, basado en la Teoría del Comportamiento Planeado realizado a partir de 3 grupos focales (n= 25). La información se analizó con la técnica Análisis Temático a partir de tres categorías definidas a priori: creencias conductuales, normativas y de control. Resultados: Los universitarios creen que alimentarse de manera saludable beneficia la salud física y mental, dentro de las desventajas de este tipo de alimentación se encuentra que la compra y preparación de alimentos saludables es más costosa y les toma mucho más tiempo que alimentarse en base a comida rápida. Paralelamente, declaran que implementar una alimentación saludable sería más sencillo si vivieran en familia y sus madres se hicieran cargo (creencias de control). Con respecto a las creencias normativas, señalaron que sus figuras parentales serían más felices si los participantes se alimentaran sanamente, pero que en lo concreto, no sienten ninguna presión social por alimentarse adecuadamente. Conclusión: Las características poco saludables de la conducta alimentaria de los universitarios, está condicionada por las creencias que subyacen a ella. Al profundizar en estas creencias se puede comprender la perspectiva del estudiante frente a su alimentación, siendo esta información clave y contextualizada para diseñar intervenciones efectivas en las universidades.


The aim of this study was to inquire into the behavioral beliefs, normative beliefs and control beliefs underlying the healthy eating in students of the Guadalajara University, México. Methods: Qualitative and exploratory study based on Ajzen's Theory of Planned Behavior, 3 focus group interviews were carried out (n:25). The information was analyzed using the Thematic Analysis method from three previously defined categories: behavioral beliefs, normative beliefs and control beliefs. Results: University students considered healthy eating to be beneficial for physical and mental health, they also believed that healthy food purchases and preparation were expensive and time consuming (behavioral beliefs). In parallel, they informed that implementing a healthy diet would be easier if their mothers helped them and if they lived in a family (control beliefs). Regarding normative beliefs, they stated that their parental figures would be happy if the participants made changes in their diet but they did not feel any particular social pressure to eat healthier. Conclusions: The eating behavior of the university students is conditioned by the beliefs that underlie the eating decision making process. By understanding student eating beliefs, we can obtained key and contextualized information to design effective interventions in the university.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Young Adult , Students/psychology , Health Knowledge, Attitudes, Practice , Feeding Behavior , Diet, Healthy , Universities , Interviews as Topic , Qualitative Research , Mexico
4.
J Pediatr Endocrinol Metab ; 29(6): 731-6, 2016 Jun 01.
Article in English | MEDLINE | ID: mdl-27054593

ABSTRACT

BACKGROUND: In this study, our aim was to analyze bone mineral density (BMD) in patients with type 1 diabetes mellitus (T1DM) and compare them with a healthy reference population; in addition, we aimed to observe the association between BMD and the following variables: age at onset, disease duration, metabolic control, pubertal stage, level of physical activity, clinical parameters and nutrient intake. METHODS: A total of 30 patients with T1DM were included in the study. BMD was determined using dual-energy X-ray densitometry (DXA). Participants with a z-score of values ≥-1 were accepted as normal; BMDs between -2 and -1 were defined as being in the low range of normality; ≤-2 were defined as having low BMD. The 25-hydroxy vitamin D level was classified as sufficient (30-100 ng/mL), insufficient (20-30 ng/mL), and deficient (<20 ng/mL). RESULTS: The percentages of patients with deficient and insufficient 25(OH) vitamin D levels were 50% and 45.8%, respectively. Lumbar spine (LS2-LS4) BMD, total body (TB) BMD and femoral neck (FN) BMD were found in the normal range for more than 80% of the subjects, with no significant differences due to gender. No strong correlations between clinical variables, biochemical parameters and nutrient intake were observed; however, a moderate positive correlation was found between serum calcium and LS2-LS4 BMD (p<0.05). Regression analysis showed that serum calcium, duration of diabetes and intake of sodium and protein are significant factors in determining LS2-LS4 BMD and TB BMD. CONCLUSIONS: Patients with T1DM had a normal mean BMD at all sites evaluated, except for two patients who had low BMD at the lumbar spine. More than 95% of patients had insufficient or deficient vitamin D levels. With respect to all the variables studied, serum calcium presented the highest significant correlation with LS2-LS4 BMD.


Subject(s)
Bone Density , Diabetes Mellitus, Type 1/metabolism , Adolescent , Adult , Child , Female , Humans , Male , Vitamin D/analogs & derivatives , Vitamin D/blood
5.
J Pediatr Endocrinol Metab ; 28(7-8): 895-902, 2015 Jul.
Article in English | MEDLINE | ID: mdl-25781527

ABSTRACT

OBJECTIVE: The aim of this study was to assess dietary intake, nutritional status, body composition, and physical activity level in a group of Chilean children and adolescents with Type 1 diabetes mellitus (T1DM), compare these parameters with the recommendations of the International Society for Pediatric and Adolescent Diabetes (ISPAD), and determine the relationships between dietary intake, body composition, and diabetes control. METHODS: A total of 30 patients with T1DM (aged 15.2±4.0 years) were included. Dietary intake was assessed using a 92-item quantitative food frequency questionnaire. Body composition was determined using dual-energy X-ray densitometry. Physical activity was assessed by means of a survey. RESULTS: The energy intake of these patients was derived from 21.4% protein, 48% carbohydrates, and 31.2% fat. The glycosylated hemoglobin (HbA1c) was significantly correlated with fat as grams per day (r: 0.363, p<0.05) and calories per day (r: 0.364, p<0.05). The mean body fat percentage in females was 31.2% and 20.2% in males (p < 0.01) and the mean amount of physical activity was 4.5±2.7 h per week. CONCLUSIONS: The study patients had a higher protein intake than recommended by ISPAD. Dietary carbohydrate intake was rather low, and dietary fat intake was the same as the limits recommended by ISPAD. Diabetic control was significantly correlated with protein, carbohydrates, fat, and sodium intake. The girls in the study had a higher percentage of body fat than the standard recommendations for their age. The level of physical activity was adequate.


Subject(s)
Body Composition , Diabetes Mellitus, Type 1/physiopathology , Diet , Exercise/physiology , Adolescent , Adult , Blood Glucose/analysis , Body Mass Index , Child , Chile , Energy Intake , Female , Follow-Up Studies , Glycated Hemoglobin/analysis , Humans , Male , Prognosis , Young Adult
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