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1.
Plants (Basel) ; 12(19)2023 Sep 27.
Article in English | MEDLINE | ID: mdl-37836147

ABSTRACT

As a result of the climate changes that are getting worse nowadays, drought stress (DS) is a major obstacle during crop life stages, which ultimately reduces tomato crop yields. So, there is a need to adopt modern approaches like a novel nutrient- and antioxidant-based formulation (NABF) for boosting tomato crop productivity. NABF consists of antioxidants (i.e., citric acid, salicylic acid, ascorbic acid, glutathione, and EDTA) and nutrients making it a fruitful growth stimulator against environmental stressors. As a first report, this study was scheduled to investigate the foliar application of NABF on growth and production traits, physio-biochemical attributes, water use efficiency (WUE), and nutritional, hormonal, and antioxidative status of tomato plants cultivated under full watering (100% of ETc) and DS (80 or 60% of ETc). Stressed tomato plants treated with NABF had higher DS tolerance through improved traits of photosynthetic efficiency, leaf integrity, various nutrients (i.e., copper, zinc, manganese, calcium, potassium, phosphorus, and nitrogen), and hormonal contents. These positives were a result of lower levels of oxidative stress biomarkers as a result of enhanced osmoprotectants (soluble sugars, proline, and soluble protein), and non-enzymatic and enzymatic antioxidant activities. Growth, yield, and fruit quality traits, as well as WUE, were improved. Full watering with application of 2.5 g NABF L-1 collected 121 t tomato fruits per hectare as the best treatment. Under moderate DS (80% of ETc), NABF application increased fruit yield by 10.3%, while, under severe DS (40% of ETc), the same fruit yield was obtained compared to full irrigation without NABF. Therefore, the application of 60% ETc × NABF was explored to not only give a similar yield with higher quality compared to 100% ETc without NABF as well as increase WUE.

2.
Diagnostics (Basel) ; 12(12)2022 Dec 03.
Article in English | MEDLINE | ID: mdl-36553041

ABSTRACT

Thoracic diseases refer to disorders that affect the lungs, heart, and other parts of the rib cage, such as pneumonia, novel coronavirus disease (COVID-19), tuberculosis, cardiomegaly, and fracture. Millions of people die every year from thoracic diseases. Therefore, early detection of these diseases is essential and can save many lives. Earlier, only highly experienced radiologists examined thoracic diseases, but recent developments in image processing and deep learning techniques are opening the door for the automated detection of these diseases. In this paper, we present a comprehensive review including: types of thoracic diseases; examination types of thoracic images; image pre-processing; models of deep learning applied to the detection of thoracic diseases (e.g., pneumonia, COVID-19, edema, fibrosis, tuberculosis, chronic obstructive pulmonary disease (COPD), and lung cancer); transfer learning background knowledge; ensemble learning; and future initiatives for improving the efficacy of deep learning models in applications that detect thoracic diseases. Through this survey paper, researchers may be able to gain an overall and systematic knowledge of deep learning applications in medical thoracic images. The review investigates a performance comparison of various models and a comparison of various datasets.

3.
Clin Med Insights Cardiol ; 14: 1179546820930015, 2020.
Article in English | MEDLINE | ID: mdl-32550769

ABSTRACT

BACKGROUND: Cardiac systolic dysfunction was potentially found in adult patients with end-stage renal disease (ESRD) who have preserved left ventricular ejection fraction (EF%). In children with ESRD, little data are available on early changes in myocardial function. This study aimed to detect the early changes in myocardial mechanics in pediatric patients with ESRD using speckle tracking echocardiography (STE). METHODS: Thirty ESRD children receiving hemodialysis (HD) and30 age-matched controls were prospectively studied. Patients underwent echocardiographic studies before and after HD. Left ventricular longitudinal strain (LS), circumferential strain (CS), and radial strain (RS) myocardial deformation parameters (strain, strain rate) were evaluated by STE. RESULTS: The LS was significantly reduced in pre-HD and post-HD patients compared with controls (P = .000). Controls showed the highest global longitudinal strain. The RS measurements did not differ significantly among the studied groups except for the inferior segment that is significantly reduced after HD compared with controls (P < .05). The CS was significantly reduced in pre-HD and post-HD patients compared with controls at the lateral and posterior segments (P = .035 and P = .013, respectively). CONCLUSION: Speckle-tracking echocardiography might detect early changes in myocardial mechanics in children with ESRD with preserved EF%.

4.
Arch Med Sci Atheroscler Dis ; 3: e18-e28, 2018.
Article in English | MEDLINE | ID: mdl-30775585

ABSTRACT

INTRODUCTION: Tissue Doppler imaging (TDI) is a relatively new echocardiography method in children with chronic kidney disease (CKD). The aims of this study were to evaluate left ventricular (LV) diastolic function in pediatric CKD patients using conventional pulsed-wave Doppler echocardiography (cPWD) and TDI methods and correlate them with BNP levels. MATERIAL AND METHODS: Thirty children on regular hemodialysis (HD) were included. Left ventricular systolic and diastolic indices and BNP levels were measured immediately before and after HD. RESULTS: After HD, LV and left atrium diameters were significantly decreased (p < 0.001 and p < 0.001, respectively). Transmitral E velocity and E/A ratio decreased (p < 0.001 and p < 0.001, respectively). Also, there were significant decreases in the early diastolic velocity E' of LV wall, septal wall, and anterior wall (p = 0.001, p = 0.004 and p < 0.001, respectively). Mean E/E' ratio and ratios of septal and lateral walls were decreased significantly (p = 0.004, p = 0.002 and p = 0.017, respectively). BNP levels decreased significantly during HD when comparing concentrations before and after HD (p < 0.001). BNP strongly correlated with LV diastolic function indices (before HD: mean E/E' (r = 0.401, p = 0.028), lateral E/E" (r = 0.291, p = 0.025), septal E'(r = -0.398, p = 0.029), lateral wall E' (r = -0.452, p = 0.012) and mean E' (r = -0.469, p = 0.009), after HD: mean E/E' (r = 0.38, p = 0.038) and lateral E/E" (r = 0.474, p = 0.008) and lateral wall E' (r = -0.270, p = 0.037)). CONCLUSIONS: The cPWD and TDI-derived LV indices are influenced by HD. The diagnostic utility of BNP in the presence of deteriorating renal function may be compromised to some extent.

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