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1.
Heliyon ; 10(10): e31228, 2024 May 30.
Article in English | MEDLINE | ID: mdl-38803883

ABSTRACT

Diabetic foot ulcer (DFU) poses a significant threat to individuals affected by diabetes, often leading to limb amputation. Early detection of DFU can greatly improve the chances of survival for diabetic patients. This work introduces FusionNet, a novel multi-scale feature fusion network designed to accurately differentiate DFU skin from healthy skin using multiple pre-trained convolutional neural network (CNN) algorithms. A dataset comprising 6963 skin images (3574 healthy and 3389 ulcer) from various patients was divided into training (6080 images), validation (672 images), and testing (211 images) sets. Initially, three image preprocessing techniques - Gaussian filter, median filter, and motion blur estimation - were applied to eliminate irrelevant, noisy, and blurry data. Subsequently, three pre-trained CNN algorithms -DenseNet201, VGG19, and NASNetMobile - were utilized to extract high-frequency features from the input images. These features were then inputted into a meta-tuner module to predict DFU by selecting the most discriminative features. Statistical tests, including Friedman and analysis of variance (ANOVA), were employed to identify significant differences between FusionNet and other sub-networks. Finally, three eXplainable Artificial Intelligence (XAI) algorithms - SHAP (SHapley Additive exPlanations), LIME (Local Interpretable Model-agnostic Explanations), and Grad-CAM (Gradient-weighted Class Activation Mapping) - were integrated into FusionNet to enhance transparency and explainability. The FusionNet classifier achieved exceptional classification results with 99.05 % accuracy, 98.18 % recall, 100.00 % precision, 99.09 % AUC, and 99.08 % F1 score. We believe that our proposed FusionNet will be a valuable tool in the medical field to distinguish DFU from healthy skin.

2.
J Pathol Inform ; 14: 100307, 2023.
Article in English | MEDLINE | ID: mdl-37025326

ABSTRACT

Lung cancer has been the leading cause of cancer-related deaths worldwide. Early detection and diagnosis of lung cancer can greatly improve the chances of survival for patients. Machine learning has been increasingly used in the medical sector for the detection of lung cancer, but the lack of interpretability of these models remains a significant challenge. Explainable machine learning (XML) is a new approach that aims to provide transparency and interpretability for machine learning models. The entire experiment has been performed in the lung cancer dataset obtained from Kaggle. The outcome of the predictive model with ROS (Random Oversampling) class balancing technique is used to comprehend the most relevant clinical features that contributed to the prediction of lung cancer using a machine learning explainable technique termed SHAP (SHapley Additive exPlanation). The results show the robustness of GBM's capacity to detect lung cancer, with 98.76% accuracy, 98.79% precision, 98.76% recall, 98.76% F-Measure, and 0.16% error rate, respectively. Finally, a mobile app is developed incorporating the best model to show the efficacy of our approach.

3.
Sci Rep ; 12(1): 21796, 2022 12 16.
Article in English | MEDLINE | ID: mdl-36526680

ABSTRACT

COVID-19 is one of the most life-threatening and dangerous diseases caused by the novel Coronavirus, which has already afflicted a larger human community worldwide. This pandemic disease recovery is possible if detected in the early stage. We proposed an automated deep learning approach from Computed Tomography (CT) scan images to detect COVID-19 positive patients by following a four-phase paradigm for COVID-19 detection: preprocess the CT scan images; remove noise from test image by using anisotropic diffusion techniques; make a different segment for the preprocessed images; and train and test COVID-19 detection using Convolutional Neural Network (CNN) models. This study employed well-known pre-trained models, including AlexNet, ResNet50, VGG16 and VGG19 to evaluate experiments. 80% of images are used to train the network in the detection process, while the remaining 20% are used to test it. The result of the experiment evaluation confirmed that the VGG19 pre-trained CNN model achieved better accuracy (98.06%). We used 4861 real-life COVID-19 CT images for experiment purposes, including 3068 positive and 1793 negative images. These images were acquired from a hospital in Sao Paulo, Brazil and two other different data sources. Our proposed method revealed very high accuracy and, therefore, can be used as an assistant to help professionals detect COVID-19 patients accurately.


Subject(s)
COVID-19 , Humans , COVID-19/diagnostic imaging , Brazil , Radionuclide Imaging , Patients , Tomography, X-Ray Computed
4.
J King Saud Univ Comput Inf Sci ; 34(6): 3226-3235, 2022 Jun.
Article in English | MEDLINE | ID: mdl-38620614

ABSTRACT

Chest X-ray image contains sufficient information that finds wide-spread applications in diverse disease diagnosis and decision making to assist the medical experts. This paper has proposed an intelligent approach to detect Covid-19 from the chest X-ray image using the hybridization of deep convolutional neural network (CNN) and discrete wavelet transform (DWT) features. At first, the X-ray image is enhanced and segmented through preprocessing tasks, and then deep CNN and DWT features are extracted. The optimum features are extracted from these hybridized features through minimum redundancy and maximum relevance (mRMR) along with recursive feature elimination (RFE). Finally, the random forest-based bagging approach is used for doing the detection task. An extensive experiment is performed, and the results confirm that our approach gives satisfactory performance compare to the existing methods with an overall accuracy of more than 98.5%.

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