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1.
Saúde em Redes ; 10(1): 9, fev. 2024.
Article in Portuguese | LILACS-Express | LILACS | ID: biblio-1554845

ABSTRACT

A disciplina Integração-Ensino-Serviço-Comunidade III (IESC III) faz parte do itinerário curricular da Universidade do Grande Rio ­ Professor José de Souza Herdy (UNIGRANRIO-AFYA) e, por ter caráter obrigatório, deve ser cursada por todos os graduandos ao decorrer do curso. Como parte da metodologia de ensino-aprendizagem, acompanhados pelos professores atribuídos ao curso, os discentes, como parte das atividades da disciplina, realizam, em sua prática, um Projeto Terapêutico Singular (PTS), seguindo as normas da Equipe de Saúde da Família (ESF), tendo a oportunidade de acompanhar uma família por meio dessa ação. Este artigo tem como objetivo relatar as experiências vivenciadas pelos discentes durante os quatro meses de IESC III em que foi posto em prática o desenvolvimento do PTS. Na percepção dos estudantes, tal ação formativa foi substancial para a construção dos futuros médicos, haja vista o contato mais próximo com a família em questão, que proporcionou a familiarização com o trabalho que é desenvolvido diariamente pelos Agentes Comunitários de Saúde. Ademais, atesta-se pelo próprio sucesso obtido ao final do trabalho, que ele oportunizou o conhecimento de realidades completamente distintas daquelas vivenciadas por cada integrante do grupo.

3.
Nursing (Ed. bras., Impr.) ; 24(274): 5357-5366, mar.2021.
Article in Portuguese | LILACS, BDENF - Nursing | ID: biblio-1222811

ABSTRACT

Objetivo: identificar a expectativa dos adolescentes sobre educação sexual; caracterizar o perfil socioeconômico e cultural dos adolescentes de uma escola da rede privada do município de São Gonçalo/RJ. Metodologia: trata-se de estudo descritivo, exploratório de natureza qualitativa, estudo de caso com coleta de dados, realizada entrevista individual a fim de obter dados socioeconômicos e culturais dos entrevistados; técnica de grupo focal que utilizou roteiro orientado por algumas perguntas norteadoras para apreensão das concepções sobre as expectativas da educação sexual. O estudo foi aprovado pelo Comitê de Ética do Hospital Universitário Antônio Pedro, sob o CAAE: 0265.0.258.000-10. Resultados: emergiram duas categorias: Papo sério: conversando com adolescentes sobre educação sexual no âmbito escolar e sociedade reafirmando tabus na questão da sexualidade. Conclusão: os adolescentes entendem que a escola e a família devem trabalhar em conjunto desempenhando papel importante na educação para sexualidade ligada à vida, à saúde, ao prazer e ao bem-estar.(AU)


Objective: to identify adolescents' expectations about sex education; characterize the socioeconomic and cultural profile of adolescents from a private school in the city of São Gonçalo / RJ. Methodology: this is a descriptive, exploratory study of a qualitative nature, a case study with data collection, an individual interview was conducted in order to obtain socioeconomic and cultural data from the interviewees; focus group technique that used a script guided by some guiding questions to apprehend the conceptions about the expectations of sex education. The study was approved by the Ethics Committee of Hospital Universitário Antônio Pedro, under CAAE: 0265.0.258.000-10. Results: two categories emerged: Serious conversation: talking to teenagers about sex education in the school and society reaffirming taboos on the issue of sexuality. Conclusion: the adolescents understand that the school and the family must work together playing an important role in education for sexuality linked to life, health, pleasure and well-being.(AU)


Objetivo: identificar las expectativas de los adolescentes sobre la educación sexual; caracterizar el perfil socioeconómico y cultural de los adolescentes de una escuela privada en la ciudad de São Gonçalo / RJ. Metodología: este es un estudio descriptivo, exploratorio de naturaleza cualitativa, un estudio de caso con recolección de datos, se realizó una entrevista individual para obtener datos socioeconómicos y culturales de los entrevistados; técnica de grupo focal que utilizaba un guión guiado por algunas preguntas orientadoras para comprender las concepciones sobre las expectativas de la educación sexual. El estudio fue aprobado por el Comité de Ética del Hospital Universitario Antônio Pedro, bajo el CAAE: 0265.0.258.000-10. Resultados: surgieron dos categorías: conversación seria: hablar con los adolescentes sobre la educación sexual en la escuela y la sociedad, reafirmando tabúes sobre el tema de la sexualidad. Conclusión: los adolescentes entienden que la escuela y la familia deben trabajar juntas, desempeñando un papel importante en la educación para la sexualidad vinculada a la vida, la salud, el placer y el bienestar.(AU)


Subject(s)
Humans , Adolescent , Sex Education , Sexuality , Adolescent Health , Socioeconomic Factors
4.
Nursing (Ed. bras., Impr.) ; 24(273): 5311-5324, fev.2021.
Article in Portuguese | BDENF - Nursing, LILACS | ID: biblio-1150400

ABSTRACT

Objetivo: conhecer a representação da masculinidade dos homens acadêmicos da Universidade Federal Fluminense e analisar suas implicações para o campo da saúde. Método: trata-se de um estudo descritivo, exploratório, de natureza qualitativa que teve como referencial metodológico a hermenêutica-dialética. Foi submetido ao Comitê de Ética do Hospital Universitário Antônio Pedro sob o CAAE 0264.0.258.000-10. Os participantes da pesquisa foram quinze acadêmicos do gênero masculino, de diferentes cursos de graduação da universidade. Utilizou-se o questionário de dados sociodemográficos e um instrumento de entrevista semiestruturada. Resultados: os depoimentos mostraram a importância de conhecer a representação que cada indivíduo possui acerca de sua masculinidade, para que melhor se compreenda o homem e suas expectativas. Conclusão: o reduzido envolvimento dos acadêmicos com os cuidados em saúde decorre em função dos modelos de masculinidade estabelecidos ao longo da vida do homem.(AU)


Objective: to know the representation of masculinity of academic men at Universidade Federal Fluminense and analyze its implications for the health field. Method: this is a descriptive, exploratory, qualitative study that used the hermeneutic-dialectic methodological framework. Submitted to the Ethics Committee of Hospital Universitário Antônio Pedro under CAAE 0264.0.258.000-10. The participants were fifteen male academics, from different undergraduate courses in university. The socio-demographic data questionnaire and a semi-structured interview instrument were used. Results: the testimonies showed the importance of knowing the representation that each individual has about his masculinity, in order to better understand the man and his expectations. Conclusion: the reduced involvement of academics in health care is due to the masculinity models established throughout the life of men.(AU)


Objetivo: conocer la representación de la masculinidad de los académicos en la Universidade Federal Fluminense y analizar sus implicaciones para el campo de la salud. Método: se trata de un estudio descriptivo, exploratorio y cualitativo que utilizó el marco metodológico hermenéutico-dialéctico. Fue presentado al Comité de Ética del Hospital Universitario Antonio Pedro bajo CAAE 0264.0.258.000-10. Los participantes de la investigación fueron quince académicos masculinos, de diferentes cursos de pregrado en la universidad. Se utilizó el cuestionario de datos sociodemográficos y un instrumento de entrevista semiestructurada. Resultados: los testimonios mostraron la importancia de conocer la representación que cada indivíduo tiene sobre su masculinidad, para comprender mejor al hombre y sus expectativas. Conclusión: la menor participación de los académicos en la atención médica se debe a los modelos de masculinidad establecidos a lo largo de la vida de los hombres.(AU)


Subject(s)
Humans , Male , Female , Adolescent , Adult , Men's Health , Masculinity , Social Behavior , Students , Universities , Surveys and Questionnaires , Qualitative Research , Men
5.
Rev. Pesqui. (Univ. Fed. Estado Rio J., Online) ; 13: 1116-1121, jan.-dez. 2021. tab
Article in English, Portuguese | BDENF - Nursing, LILACS | ID: biblio-1255048

ABSTRACT

Objetivo: Descrever o perfil sóciodemográfico, sexual e reprodutivo, e a prevalência da disfunção sexual em mulheres adultas atendidas do Hospital Universitário. Método: estudo quantitativo, descritivo e transversal. Avaliaram-se 267 mulheres adultas entre 25 e 49 anos com pelo menos uma relação sexual na vida. Resultados:constatou-se associação significativa das disfunções sexuais femininas com coitarca menor que 15 anos, frequência de uma relação sexual mensal ou menos e lactação. A prevalência de dispaurenia foi encontrada em 30,3% das entrevistadas e vaginismo em 26,2 %. Conclusão: percebe-se que medidas preventivas minimizam a ocorrência das disfunções como: facilitar o acesso à informação, promoção e prevenção de saúde, e programas de capacitação e educação permanente. É importante construir uma abordagem holística e esforço multidisciplinar, visto que a disfunção sexual feminina constitui um largo espectro de dificuldades


Objective:To describe the sociodemographic, sexual and reproductive profile, the prevalence of sexual dysfunction in adult women attended at the University Hospital. Method:quantitative, descriptive and cross-sectional study. Total of 267 adult women between the ages of 25 and 49 with at least one sexual intercourse were evaluated. Results: there was a significant association of female sexual dysfunction with coitarca younger than 15 years, frequency of monthly or less sexual intercourse, and lactation. The prevalence of dyspaurenia was found in (30.3%) of the interviewees and vaginismus in (26.2%). Conclusion: noticed that preventive measures minimize the occurrence of dysfunctions such: facilitating access to information, promotion and prevention of health, training and continuing education programs. Is important to build holistic approach and multidisciplinary effort, since female sexual dysfunction constitutes broad spectrum of difficulties


Objetivo: Describir el perfil sociodemográfico, sexual y reproductivo, la prevalencia de la disfunción sexual en mujeres adultas atendidas del Hospital Universitario. Método: estudio cuantitativo, descriptivo y transversal. Evaluaron 267 mujeres adultas entre 25 y 49 años con menos una relación sexual en vida. Resultados: se constató una asociación significativa de las disfunciones sexuales femeninas con coito menor de 15 años, frecuencia de una relación sexual mensual o menos y lactancia. La prevalencia de dispaurenia fue encontrada em (30,3%) de entrevistadas y el vaginismo (26,2%). Conclusión: percibe que medidas preventivas minimizan la ocurrencia de las disfunciones como: facilitar el acceso a información, promoción y prevención de salud, programas de capacitación y educación permanente. Es importante construir enfoque holístico y esfuerzo multidisciplinario, ya que la disfunción sexual femenina constituye un amplio espectro de dificultades


Subject(s)
Humans , Female , Adult , Middle Aged , Sexual Dysfunction, Physiological/epidemiology , Socioeconomic Factors , Prevalence , Cross-Sectional Studies , Reproductive Health , Hospitals, University
6.
Rev. Pesqui. (Univ. Fed. Estado Rio J., Online) ; 13: 1349-1353, jan.-dez. 2021.
Article in English, Portuguese | LILACS, BDENF - Nursing | ID: biblio-1291349

ABSTRACT

Objetivo: Conhecer fatores relacionados à qualidade de vida e saúde de trabalhadores de um colégio universitário. Métodos: pesquisa quantitativa, realizada por meio de inquérito epidemiológico, utilizando-se questionário autoaplicado e dados clínicos. Resultados: participaram da pesquisa 106 trabalhadores, 74,5% do sexo feminino, com média de idade de 38 anos (DP±12,4), onde 92,5% relataram não fumar e 58,5% não beber álcool; 50,9% afirmou ser sedentário. Os dados clínicos demonstraram que 44,9% apresentaram pressão alterada e 11,3% glicemia elevada. Na análise dos quadrantes de exposição ao estresse, o trabalho ativo alocou maior número de profissionais (50%) e a suspeição de transtorno mental comum entre os trabalhadores foi de 22,6%. Na análise bivariada, observou-se associação entre ser solteiro e trabalho ativo (p=0,040). Conclusão: observa-se que há predominância de grau mediano de estresse no trabalho e hábitos de vida pouco saudáveis. Sabe-se que esses achados contribuem para maior ocorrência de problemas de saúde


Objetivo: Conocer factores relacionados con calidad de vida y salud de trabajadores en un colegio universitario. Métodos: investigación cuantitativa, realizada mediante encuesta epidemiológica, utilizando cuestionario autoadministrado y datos clínicos. Resultados: 106 trabajadores participaron de la investigación, 74.5% mujeres, con edad media de 38 años (SD ± 12.4), donde 92.5% informaron no fumar y 58.5% no tomar alcohol; El 50,9% dijo que eran sedentarios. Los datos clínicos mostraron que el 44,9% tenía presión arterial anormal y el 11,3% de glucosa en sangre alta. En el análisis de los cuadrantes de exposición al estrés, el trabajo activo asignó un mayor número de profesionales (50%) y la sospecha de trastorno mental común entre los trabajadores fue del 22,6%. En el análisis bivariado, se observó asociación entre trabajo individual y trabajo activo (p = 0.040). Conclusión: se observa que hay un predominio del grado medio de estrés en trabajo y hábitos de vida poco saludables. Se sabe que estos hallazgos contribuyen a una mayor ocurrencia de problemas de salud


Objective:To know factors related to the quality of life and health of workers at a university college. Methods: quantitative research, carried out by means of an epidemiological survey, using a self-administered questionnaire and clinical data. Results: 106 workers participated in the research, 74.5% female, with a mean age of 38 years (SD ± 12.4), where 92.5% reported not smoking and 58.5% not drinking alcohol; 50.9% said they were sedentary. Clinical data showed that 44.9% had abnormal blood pressure and 11.3% high blood glucose. In the analysis of the stress exposure quadrants, active work allocated a greater number of professionals (50%) and the suspicion of common mental disorder among workers was 22.6%. In the bivariate analysis, an association was observed between being single and active work (p = 0.040). Conclusion: it is observed that there is a predominance of median degree of stress at work and unhealthy lifestyle habits. It is known that these findings contribute to a greater occurrence of health problems


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Quality of Life , Health Behavior , Occupational Health/statistics & numerical data , Educational Personnel/statistics & numerical data , Occupational Stress , Schools/statistics & numerical data , Health Surveys , Life Style
8.
J Neuroimmunol ; 340: 577163, 2020 03 15.
Article in English | MEDLINE | ID: mdl-31982706

ABSTRACT

In multiple sclerosis (MS), cognitive dysfunction is common but difficult to treat. We analyzed the impact of dimethyl fumarate, an MS drug with neuroprotective properties, in spatial memory performance in a mouse model of MS and looked for structural correlates in the hippocampus. Treated mice presented better cognitive performance which was not associated with structural hippocampal damage but with decreased demyelination in the fimbria. Dimethyl fumarate, even if initiated after hindlimb paralysis, ameliorated memory deficits in the MS mouse model due, at least in part, to its positive impact in the demyelination of the main hippocampal output pathway.


Subject(s)
Cognition/drug effects , Dimethyl Fumarate/pharmacology , Encephalomyelitis, Autoimmune, Experimental/pathology , Hippocampus/drug effects , Neuroprotective Agents/pharmacology , Animals , Female , Hippocampus/pathology , Mice , Mice, Inbred C57BL
9.
Nursing (Ed. bras., Impr.) ; 22(251): 2937-2942, abr.2019.
Article in Portuguese | LILACS, BDENF - Nursing | ID: biblio-998896

ABSTRACT

A pesquisa objetivou analisar percepção dos enfermeiros da Estratégia Saúde da Família do Território de Manguinhos sobre a sexualidade infantil e a implicação desta percepção para o cuidado à saúde da criança. Trata-se de um estudo descritivo, exploratório e de natureza qualitativa. Realizado no Centro de Saúde Escola Germano Sinval Faria e Clínica da Família Victor Valla no Complexo de Manguinhos, no Município do Rio de Janeiro, onde está localizado e é campo de ensino e pesquisa para ENSP/FIOCRUZ, com 8 enfermeiros entrevistados atuantes na Estratégia Saúde da Família. Utilizou-se o método de interpretação de sentidos, baseando-se em princípios hermenêutico-dialéticos. Os depoimentos evidenciam que o despreparo do profissional sobre o assunto e a implicação desta percepção para o cuidado à saúde da criança, leva a um cuidado incompleto. Neste sentido, refletimos sobre a importância da atuação do enfermeiro como profissional de saúde nas consultas, onde pode colaborar de maneira positiva com a educação de pais e crianças a respeito da sexualidade.(AU)


The aim of the research was to analyze nurses' perceptions of the Family Health Strategy of the Manguinhos Territory on child sexuality and the implication of this perception for the health care of the child. It is a descriptive, exploratory and qualitative study. Held at the Germano Sinval Faria School of Health and Victor Valla Family Clinic in the Manguinhos Complex, in the city of Rio de Janeiro, where it is located and is a teaching and research field for ENSP/FIOCRUZ, with 8 nurses interviewed in the Health Strategy of the family. The method of interpretation of senses was used, based on hermeneutic-dialectical principles. The testimonies show that the professional's unpreparedness about the subject and the implication of this perception for the child's health care leads to incomplete care. In this sense, we reflect on the importance of nurses acting as health professionals in consultations, where they can collaborate in a positive way with the education of parents and children regarding sexuality.(AU)


La investigación objetivó analizar la percepción de los enfermeros de la Estrategia Salud de la Familia del Territorio de Manguinhos sobre la sexualidad infantil y la implicación de esta percepción para el cuidado de la salud del niño. Se trata de un estudio descriptivo, exploratorio y de naturaleza cualitativa. En el municipio de Río de Janeiro, donde está ubicado y es campo de enseñanza e investigación para ENSP / FIOCRUZ, con 8 enfermeros entrevistados actuantes en la Estrategia Salud, en el Centro de Salud Escuela Germano Sinval Faria y Clínica de la Familia Victor Valla en el Complejo de Manguinhos, en el Municipio de Río de Janeiro, donde está localizado y es campo de enseñanza e investigación para ENSP / FIOCRUZ, con 8 enfermeros entrevistados actuantes en la Estrategia Salud de la familia. Se utilizó el método de interpretación de sentidos, basándose en principios hermenéutico-dialécticos. Los testimonios evidencian que la despreparación del profesional sobre el tema y la implicación de esta percepción para el cuidado a la salud del niño, lleva a un cuidado incompleto. En este sentido, reflexionamos sobre la importancia de la actuación del enfermero como profesional de salud en las consultas, donde puede colaborar de manera positiva con la educación de padres y niños respecto a la sexualidad.(AU)


Subject(s)
Humans , Child , Child Care , Child Health , Sexuality , Pediatric Nursing , Sex Education
10.
Sci Rep ; 9(1): 2005, 2019 02 14.
Article in English | MEDLINE | ID: mdl-30765864

ABSTRACT

Aging is associated with cognitive decline. Herein, we studied a large cohort of old age and young adult male rats and confirmed that, as a group, old  rats display poorer spatial learning and behavioral flexibility than younger adults. Surprisingly, when animals were clustered as good and bad performers, our data revealed that while in younger animals better cognitive performance was associated with longer dendritic trees and increased levels of synaptic markers in the hippocampus and prefrontal cortex, the opposite was found in the older group, in which better performance was associated with shorter dendrites and lower levels of synaptic markers. Additionally, in old, but not young individuals, worse performance correlated with increased levels of BDNF and the autophagy substrate p62, but decreased levels of the autophagy complex protein LC3. In summary, while for younger individuals "bigger is better", "smaller is better" is a more appropriate aphorism for older subjects.


Subject(s)
Cognitive Aging/physiology , Animals , Autophagy , Brain-Derived Neurotrophic Factor/metabolism , Cohort Studies , Male , Neurons/cytology , Rats , Rats, Wistar , Synapses/metabolism
11.
Rev. lab. clín ; 11(4): 222-226, oct.-dic. 2018. tab, graf
Article in English | IBECS | ID: ibc-176921

ABSTRACT

Introduction: Hereditary spastic paraplegia is a group of inherited neurological disorders with predominant manifestations of lower extremity weakness and severe spasticity. This is a genetically heterogeneous disorder very difficult to distinguish clinically with many genes described. Few patients with this condition have been previously reported. Patient and methods: We present a case of a 5 years old girl, born from consanguineous parents, with severe ataxia and progressive spasticity of low limbs. Due to the severity of the symptoms and the need for early diagnosis, next generation sequencing study of 37 genes implicated in spastic paraplegia was performed. Results: A novel pathological variant in FA2H gene was discovered. Father, mother and brother were heterozygous carriers. Conclusions: Spastic paraplegia due to mutations in FA2H is an under diagnosed condition, and it should always be considered in childhood onset of progressive pyramidal dysfunction. Next Generation Sequencing allows a simultaneous analysis of many genes, enables a fast diagnosis in complex disorders


Introducción: La paraparesia espástica es un grupo de enfermedades neurológicas hereditarias que cursan con debilidad de las extremidades inferiores y espasticidad severa. Es una enfermedad muy heterogénea, con muchos genes descritos y muy difícil de distinguir clínicamente. Hay pocos pacientes descritos con esta enfermedad. Pacientes y métodos: Se presenta un caso de una niña de 5 años, de padres consanguíneos, con una ataxia severa y espasticidad progresiva de los miembros inferiores. Dada la gravedad de la clínica y la necesidad de un diagnóstico temprano, se decide realizar un panel de secuenciación masiva de 37 genes implicados en paraparesia espástica. Resultados: Los resultados muestran una variante patológica no descrita previamente en el gen FA2H. El padre, la madre y el hermano resultan portadores heterocigotos. Conclusiones: La paraparesia espástica debida a mutaciones en el gen FA2H está infradiagnosticada y debería ser considerada siempre que aparezcan síntomas en la infancia de disfunción piramidal grave y progresiva. Los paneles de secuenciación masiva con el análisis simultáneo de varios genes están permitiendo un diagnóstico más rápido en enfermedades complejas


Subject(s)
Humans , Female , Child, Preschool , Spastic Paraplegia, Hereditary/genetics , High-Throughput Nucleotide Sequencing/methods , Genetic Markers , /methods , Pyramidal Tracts/physiopathology
12.
Rev. baiana enferm ; 32: e26104, 2018.
Article in Portuguese | LILACS, BDENF - Nursing | ID: biblio-990530

ABSTRACT

Objetivo conhecer os fatores relacionados ao não uso de medidas preventivas das infecções sexualmente transmissíveis durante o período gravídico. Método estudo descritivo, exploratório, com abordagem qualitativa, realizado com gestantes num hospital universitário do Rio de Janeiro, Brasil. A coleta dos dados foi feita mediante a aplicação de entrevista semiestruturada, no ano de 2017. Resultados as entrevistadas conheciam as principais infecções; não utilizavam nenhum método de prevenção; obtiveram informações sobre as infecções pelas mídias sociais, grupos de planejamento familiar e praticamente nenhuma durante o pré-natal; consideraram a conjugalidade um fator de proteção. Conclusão esta pesquisa desvelou fatores relacionados à não adoção de medidas preventivas das infecções sexualmente transmissíveis por mulheres e seus parceiros durante a gestação.


Objetivo conocer los factores relacionados a la no aplicación de medidas preventivas de enfermedades de transmisión sexual durante el período de gestación. Método estudio descriptivo, exploratorio, con abordaje cualitativo, realizado con embarazadas en un hospital universitario de Rio de Janeiro, Brasil. Datos recolectados mediante aplicación de entrevista semiestructurada, durante 2017. Resultados las entrevistadas conocían las principales enfermedades; no utilizaban ningún método de prevención; obtuvieron información sobre las enfermedades a través de las redes sociales, grupos de planificación familiar, y prácticamente ninguna durante el prenatal; consideraban la vida en pareja como factor de protección. Conclusión esta investigación develó factores relacionados a la no adopción de medidas preventivas de enfermedades de transmisión sexual en mujeres y sus compañeros durante el embarazo.


Objective To know the factors associated with the non-use of measures to prevent sexually transmitted diseases during pregnancy. Method A descriptive and exploratory study with a qualitative approach was carried out with pregnant women in a teaching hospital in the state of Rio de Janeiro, Brazil. Data collection was carried out in 2017 with the use of semi-structured interviews. Results the pregnant women interviewed had knowledge about the main diseases; they did not make use of any prevention methods; they had access to information about diseases through social media, family planning groups, and hardly any during prenatal; and they considered conjugality a protection factor. Conclusion The present study presented factors associated with the non-adoption of sexually transmitted disease prevention measures by pregnant women and their partners during pregnancy.


Subject(s)
Humans , Female , Pregnancy , Adolescent , Adult , Prenatal Care , Pregnancy , Sexually Transmitted Diseases/prevention & control , Women's Health , Obstetric Nursing , Unified Health System , Health Education , Infection Control , Condoms , Comprehensive Health Care , Sexuality , Pregnant Women , Disease Prevention , Family Development Planning , Social Networking , Social Media
13.
Rev. neurol. (Ed. impr.) ; 64(7): 299-304, 1 abr., 2017. tab
Article in Spanish | IBECS | ID: ibc-161601

ABSTRACT

Introducción. El síndrome de piernas inquietas (SPI) es una patología neurológica común. Se ha relacionado con diferentes trastornos psiquiátricos, especialmente con el trastorno por déficit de atención/hiperactividad (TDAH). Objetivos. El objetivo principal fue describir la frecuencia del SPI en pacientes pediátricos diagnosticados de TDAH. Los objetivos secundarios del estudio fueron describir otros trastornos del sueño en pacientes con TDAH. Pacientes y métodos. Se realizó un estudio descriptivo prospectivo multicéntrico en nueve centros españoles de niños de 6-18 años con diagnóstico de TDAH entre enero y junio de 2015. Los datos fueron recogidos por 13 médicos investigadores mediante entrevista con el padre/cuidador y con el menor. Para valorar el grado de funcionamiento de los pacientes con TDAH se utilizó la Children’s Global Assessment Scale. Se aplicó la Sleep Disturbance Scale for Children de Bruni para el cribado del trastorno de sueño de la infancia. Resultados. Se recogió una muestra de 73 pacientes. Cinco pacientes (6,8%) cumplen criterios diagnósticos de SPI: cuatro de ellos definitivos y uno probable. Conclusiones. El SPI es una entidad frecuente en la edad adulta, pero también en la adolescencia y en la infancia. Los pacientes con TDAH tienen un riesgo aumentado de presentar de manera concomitante un SPI (AU)


Introduction. Restless legs syndrome (RLS) is a common neurological disease. RLS has been linked to various psychiatric disorders, especially with attention deficit hyperactivity disorder (ADHD). Aims. The main objective was to describe the frequency of RLS in pediatric patients diagnosed with ADHD. Secondary objectives of the study were describe other sleep disorders in ADHD patients. Patients and methods. A multicentre prospective study was conducted in nine Spanish centers. We included children aged 6-18 years diagnosed with ADHD between January and June 2015. Data were collected by 13 researchers doctors through an interview with the parent/caregiver and with the child. To assess the degree of functioning of patients with ADHD we used the Children’s Global Assessment Scale. The Sleep Disturbance Scale for Children was applied to screening sleep disorders in childhood. Results. A sample of 73 patients was collected. Five patients (6.8%) met diagnostic criteria for RLS: four of them definitive and one probable. Conclusions. RLS is a frequent condition in adulthood but also in adolescence and childhood. ADHD patients have an increased risk of an RLS (AU)


Subject(s)
Humans , Male , Female , Child , Adolescent , Restless Legs Syndrome/complications , Restless Legs Syndrome/epidemiology , Attention Deficit Disorder with Hyperactivity/complications , Attention Deficit Disorder with Hyperactivity/diagnosis , Sleep Wake Disorders/complications , Prospective Studies , Analysis of Variance , Medical History Taking , Ferritins/therapeutic use , Levodopa/therapeutic use , Iron/therapeutic use
14.
Rev. enferm. UFPE on line ; 11(supl.2): 1052-1061, fev.2017. ilus
Article in Portuguese | BDENF - Nursing | ID: biblio-1032401

ABSTRACT

Objetivos: identificar, em literatura científica, as ações da enfermagem direcionadas ao idoso na Estratégia Saúde da Família e discutir as ações da enfermagem ao idoso na Estratégia Saúde da Família perante a Política Nacional de Saúde da Pessoa Idosa e Política Nacional de Atenção Básica. Método: revisão integrativa, a qual teve como questão de pesquisa >. A busca de dados relativos ao período de 2004 a 2014 ocorreu nas bases de dados LILACS e MEDLINE. Foram selecionados cinco artigos que atenderam aos critérios estabelecidos. Resultados: as ações da enfermagem identificadas não contemplam plenamente a Política Nacional de Saúde da Pessoa Idosa e Política Nacional de Atenção Básica. Conclusão: é fundamental a participação da enfermagem em atividades de educação permanente com temáticas voltadas ao idoso.


Subject(s)
Male , Female , Humans , Aged , Aged, 80 and over , Nursing Care , Education, Continuing , Public Health Nursing , National Health Strategies , Health Policy , Health of the Elderly , MEDLINE , Health Education , Nurses , House Calls
15.
Rev Neurol ; 62(2): 61-7, 2016 Jan 16.
Article in Spanish | MEDLINE | ID: mdl-26758352

ABSTRACT

INTRODUCTION: Sleep disorders are common in children with neurological disorders. The aim of this study is to know the opinion of neuropediatricians and the prevalence of these disturbances in Spain. PATIENTS AND METHODS: Multicenter cross-sectional study (12 Spanish hospitals, 15 researchers). BEARS survey was collected in three groups: A (2-5 years), (6-12 years), and C (> 12 years). The opinion of neuropediatricians was also collected. RESULTS: 939 questionnaires were filled. The main results in groups B and C were ADHD (32.4% and 30.1% respectively) and headache (25.1% and 27.6% respectively), whereas in group A neurodevelopmental disorders (32.4%) and epilepsy (21.4%) were the main diagnoses. Disturbances in at least one area of sleep were found in 92% of children in group A (n = 209, mean 3 years), 64.2% in group B (n = 534, mean 9.4 years) and 58.2% in group C (n = 196, mean 13.7 years). Sixty-one surveys were answered by neuropediatricians (16.75% of the total sent), estimating that less than a quarter of the patients (24.5%) suffered. Even, up to 23% of doctors claimed that the prevalence of sleep disorders was < 10%. CONCLUSIONS: 58-92% of parents-patients under follow up at a neuropediatrician office in Spain have some degree of disturbed sleep. Although most neurologists emphasize the importance of an early diagnosis and treatment of sleep disorders in children with neurological disorders, its frequency is often underestimated (risk of underdiagnosis).


TITLE: Importancia de los problemas de sueño en los niños con cefalea y otros trastornos del neurodesarrollo en las consultas de neuropediatria.Introduccion. Los trastornos de sueño son frecuentes en niños con trastornos neurologicos. El objetivo del estudio es conocer la opinion de los neuropediatras y su prevalencia real en España. Pacientes y metodos. Estudio transversal multicentrico (12 hospitales españoles, 15 investigadores). Se administro la encuesta Bedtime, Excesive Daytime Sleepiness, Awakenings, Regularity, Sleep-Disordered Breathing (BEARS) y se definieron tres grupos: A (2-5 años), B (6-12 años) y C (> 12 años). Asimismo, se recogio la opinion de neuropediatras de la Sociedad Española de Neuropediatria mediante una encuesta anonima. Resultados. Se recogieron 939 encuestas. Los principales motivos de consulta en los grupos B y C fueron trastorno por deficit de atencion/hiperactividad (32,4% y 30,1%, respectivamente) y cefalea (25,1% y 27,6%, respectivamente), y en el grupo A, los trastornos del neurodesarrollo (32,4%) y la epilepsia (21,4%). Al menos un area del sueño alterada se encontro en el 92,9% de niños del grupo A (n = 209; media: 3 años), en el 64,2% del grupo B (n = 534; media: 9,4 años) y en el 58,2% del grupo C (n = 196; media: 13,7 años). Se recibieron 61 encuestas respondidas por los neuropediatras (16,75% de las enviadas), quienes estimaban que los trastornos del sueño afectaban a menos de una cuarta parte de sus pacientes (24,5%), y hasta un 23% afirmo que la prevalencia era inferior al 10%. Conclusion. El 58-92% de los padres-pacientes que acuden a consultas de neuropediatria refiere tener algun aspecto del sueño alterado. Aunque la mayoria de los neuropediatras subraya la importancia de un diagnostico y tratamiento de los trastornos de sueño de los niños con trastornos neurologicos, se suele infraestimar su frecuencia e importancia.


Subject(s)
Headache/complications , Neurodevelopmental Disorders/complications , Sleep Wake Disorders/complications , Sleep Wake Disorders/epidemiology , Adolescent , Attitude of Health Personnel , Child , Child, Preschool , Cross-Sectional Studies , Female , Health Surveys , Humans , Male , Neurology , Pediatrics , Prevalence , Prospective Studies , Spain/epidemiology
16.
Rev. neurol. (Ed. impr.) ; 62(2): 61-67, 16 ene., 2016. tab
Article in Spanish | IBECS | ID: ibc-148759

ABSTRACT

Introducción. Los trastornos de sueño son frecuentes en niños con trastornos neurológicos. El objetivo del estudio es conocer la opinión de los neuropediatras y su prevalencia real en España. Pacientes y métodos. Estudio transversal multicéntrico (12 hospitales españoles, 15 investigadores). Se administró la encuesta Bedtime, Excesive Daytime Sleepiness, Awakenings, Regularity, Sleep-Disordered Breathing (BEARS) y se definieron tres grupos: A (2-5 años), B (6-12 años) y C (> 12 años). Asimismo, se recogió la opinión de neuropediatras de la Sociedad Española de Neuropediatría mediante una encuesta anónima. Resultados. Se recogieron 939 encuestas. Los principales motivos de consulta en los grupos B y C fueron trastorno por déficit de atención/hiperactividad (32,4% y 30,1%, respectivamente) y cefalea (25,1% y 27,6%, respectivamente), y en el grupo A, los trastornos del neurodesarrollo (32,4%) y la epilepsia (21,4%). Al menos un área del sueño alterada se encontró en el 92,9% de niños del grupo A (n = 209; media: 3 años), en el 64,2% del grupo B (n = 534; media: 9,4 años) y en el 58,2% del grupo C (n = 196; media: 13,7 años). Se recibieron 61 encuestas respondidas por los neuropediatras (16,75% de las enviadas), quienes estimaban que los trastornos del sueño afectaban a menos de una cuarta parte de sus pacientes (24,5%), y hasta un 23% afirmó que la prevalencia era inferior al 10%. Conclusión. El 58-92% de los padres-pacientes que acuden a consultas de neuropediatría refiere tener algún aspecto del sueño alterado. Aunque la mayoría de los neuropediatras subraya la importancia de un diagnóstico y tratamiento de los trastornos de sueño de los niños con trastornos neurológicos, se suele infraestimar su frecuencia e importancia (AU)


Introduction. Sleep disorders are common in children with neurological disorders. The aim of this study is to know the opinion of neuropediatricians and the prevalence of these disturbances in Spain. Patients and methods. Multicenter cross-sectional study (12 Spanish hospitals, 15 researchers). BEARS survey was collected in three groups: A (2-5 years), (6-12 years), and C (> 12 years). The opinion of neuropediatricians was also collected. Results. 939 questionnaires were filled. The main results in groups B and C were ADHD (32.4% and 30.1% respectively) and headache (25.1% and 27.6% respectively), whereas in group A neurodevelopmental disorders (32.4%) and epilepsy (21.4%) were the main diagnoses. Disturbances in at least one area of sleep were found in 92% of children in group A (n = 209, mean 3 years), 64.2% in group B (n = 534, mean 9.4 years) and 58.2% in group C (n = 196, mean 13.7 years). Sixty-one surveys were answered by neuropediatricians (16.75% of the total sent), estimating that less than a quarter of the patients (24.5%) suffered. Even, up to 23% of doctors claimed that the prevalence of sleep disorders was < 10%. Conclusions. 58-92% of parents-patients under follow up at a neuropediatrician office in Spain have some degree of disturbed sleep. Although most neurologists emphasize the importance of an early diagnosis and treatment of sleep disorders in children with neurological disorders, its frequency is often undesestimated (risk of underdiagnosis) (AU)


Subject(s)
Humans , Male , Female , Child , Headache/complications , Headache/epidemiology , Sleep Wake Disorders/complications , Sleep Wake Disorders/epidemiology , Nervous System Diseases/complications , Nervous System Diseases/epidemiology , Sleep Initiation and Maintenance Disorders/complications , Sleep Initiation and Maintenance Disorders/epidemiology , Cross-Sectional Studies/statistics & numerical data , Health Surveys/methods , Health Surveys/statistics & numerical data , Societies, Medical/standards , Developmental Disabilities/complications , Prospective Studies , Surveys and Questionnaires
17.
Mol Neurobiol ; 53(7): 4745-53, 2016 09.
Article in English | MEDLINE | ID: mdl-26328538

ABSTRACT

The exposure to high glucocorticoids (GC) triggers neuronal atrophy and cognitive deficits, but the exact cellular mechanisms underlying the GC-associated dendritic remodeling and spine loss are still poorly understood. Previous studies have implicated sustained GC elevations in neurodegenerative mechanisms through GC-evoked hyperphosphorylation of the cytoskeletal protein Tau while Tau mislocation has recently been proposed as relevant in Alzheimer's disease (AD) pathology. In light of the dual cytoplasmic and synaptic role of Tau, this study monitored the impact of prolonged GC treatment on Tau intracellular localization and its phosphorylation status in different cellular compartments. We demonstrate, both by biochemical and ultrastructural analysis, that GC administration led to cytosolic and dendritic Tau accumulation in rat hippocampus, and triggered Tau hyperphosphorylation in epitopes related to its malfunction (Ser396/404) and cytoskeletal pathology (e.g., Thr231 and Ser262). In addition, we show, for the first time, that chronic GC administration also increased Tau levels in synaptic compartment; however, at the synapse, there was an increase in phosphorylation of Ser396/404, but a decrease of Thr231. These GC-triggered Tau changes were paralleled by reduced levels of synaptic scaffolding proteins such as PSD-95 and Shank proteins as well as reduced dendritic branching and spine loss. These in vivo findings add to our limited knowledge about the underlying mechanisms of GC-evoked synaptic atrophy and neuronal disconnection implicating Tau missorting in mechanism(s) of synaptic damage, beyond AD pathology.


Subject(s)
Glucocorticoids/toxicity , Hippocampus/chemistry , Hippocampus/pathology , tau Proteins/analysis , Animals , Hippocampus/drug effects , Hippocampus/metabolism , Male , Maze Learning/drug effects , Maze Learning/physiology , Rats , Rats, Wistar , tau Proteins/metabolism
18.
Rev. enferm. UFPE on line ; 10(4): 3608-3619, 2016. tab
Article in English, Portuguese | BDENF - Nursing | ID: biblio-1031624

ABSTRACT

Objetivos: identificar a Prevenção Quaternária (PQ) e discutir suas formas de inserção na atenção primária à saúde. Método: revisão integrativa com coleta dados de 01/09/14 a 10/01/15 nas bases de dados: LILACS, IBECS, PUBMED/MEDLINE, biblioteca virtual SciELO, Periódico CAPES, Minerva-UFRJ e entre 2004 a 2014, com finalidade de responder à questão norteadora << Como a PQ se insere na atenção primária à saúde através das principais bases de dados? >> Resultados: destacaram-se oito artigos: as iatrogenias nos tratamentos inadequados e reabilitação que não prioriza o apoio familiar; o conceito de PQ. Esta pode evitar o congestionamento no sistema de saúde e reduzir os gastos no planejamento familiar. Há a ênfase nas ações de cuidado na saúde da família com menor intensidade invasiva. Conclusão: as lacunas dos conhecimentos são um posicionamento profissional mais ético e menos corporativista, assim como a inclusão do paciente em seu processo terapêutico.(AU)


Objectives: to identify the Quaternary prevention (QP) and discuss the ways of integration into primary health care. Method: an integrative review with collecting data from 09.01.14 to 10.01.15 in the databases: LILACS, IBECS, PubMed/MEDLINE, virtual library SciELO, Journal CAPES, Minerva-UFRJ and between 2004-2014 to answer the guiding question << How QP is included in the primary health care through the main databases? >> Results: eight articles were highlighted: the iatrogenic in inappropriate treatment and rehabilitation that does not prioritize family support; the term QP. It can avoid congestion in the health system as well as reduce spending on family planning. There is an emphasis on actions in the family health care with less invasive intensity. Conclusion: gaps in knowledge are more ethical professional positioning and less corporatist, as well as the inclusion of patients in its therapeutic process.(AU)


Objetivos: identificar la prevención cuaternaria (PC) y discutir sus formas de inserción en la atención primaria a la salud. Método: revisión integradora con recolección de datos de 01/09/14 a 10/01/15 en las bases de datos: LILACS, IBECS, PUBMED/MEDLINE, biblioteca virtual SciELO, Periódico CAPES, Minerva-UFRJ y entre 2004 a 2014, con la finalidad de responder a la pregunta guiadora << ¿Cómo la PC se insiere en la atención primaria a la salud a través de las principales bases de datos? >> Resultados: ocho artículos seleccionados fueron destaques: las iatrogenias en los tratamientos inadecuados y la rehabilitación que no prioriza el apoyo familiar; el concepto de PC. Puede evitar el congestionamiento en el sistema de salud así como reducir los gastos en el planeamiento familiar. Hay énfasis em las acciones en el cuidado a la salud de la familia con menor intensidad invasiva. Conclusión: las lagunas de los conocimientos son un posicionamiento profesional más ético y menos corporativista, así como la inclusión del paciente en su proceso terapéutico.(AU)


Subject(s)
Humans , Male , Female , Primary Health Care , Health Human Resource Training , Health Personnel , Quaternary Prevention , Public Health , Unified Health System , MEDLINE , PubMed
19.
Rev Neurol ; 54(1): 17-23, 2012 Jan 01.
Article in Spanish | MEDLINE | ID: mdl-22187208

ABSTRACT

INTRODUCTION: Some papers published in the literature have shown that patients can present behavioural disorders and learning difficulties in benign childhood epilepsies (BCE). AIMS: To review the patients diagnosed with BCE in our hospital and to determine whether they present such disorders. PATIENTS AND METHODS: The study consisted in a retrospective review of the medical records of patients diagnosed with BCE. An electroencephalogram (EEG) or video-EEG-polygraph recordings were performed on all patients during sleep. The Wechsler Intelligence Scale for Children was used to evaluate intelligence. RESULTS: Data were collected for 102 patients diagnosed with BCE. Dispersed attention was observed in 51.6% of the patients with rolandic epilepsy and 16.2% displayed an impulsive temperament. In the group of patients with Panayiotopoulos syndrome, 30.3% displayed dispersed attention and 27.3% presented an impulsive temperament. A psychometric evaluation was carried out in 43 patients. The overall mean intelligence quotient was 95 (range: 55-126). In the three groups, academic achievement was good in approximately half the sample, regular in about 30% and poor in around 15%. In the group with rolandic epilepsy, the EEG showed a relation between frontal (p = 0.039) and occipital paroxysms (p = 0.004) and poorer academic achievement. In this group, the children with behaviours classed as dispersed, impulsive or hyperactive showed left-side paroxysms more frequently (p = 0.030). CONCLUSIONS: BCE are conditions with a good prognosis, but seem to be associated to learning and behavioural disorders. Neuropsychological studies should be conducted on these patients to detect these disorders.


Subject(s)
Child Behavior Disorders/etiology , Epilepsy, Rolandic/complications , Epilepsy, Rolandic/physiopathology , Learning Disabilities/etiology , Child , Child, Preschool , Electroencephalography , Epilepsy, Rolandic/diagnosis , Female , Humans , Intelligence , Male , Prognosis , Retrospective Studies , Syndrome , Wechsler Scales
20.
Eur J Paediatr Neurol ; 16(2): 200-2, 2012 Mar.
Article in English | MEDLINE | ID: mdl-21798772

ABSTRACT

Antiepileptic hypersensitivity syndrome (AHS) is a potentially life-threatening syndrome in pediatric cases. It is associated with aromatic anticonvulsivant drugs and others antibiotics with or without associated reactivation of virus. The pathogenesis of the process is not clear. Clinical feature of this syndrome include cutaneous reactions, fever and lymphadenopathies, but different organs can be involved. In laboratory analyses we can find leucocytosis, eosinophilia, and increase in transaminase levels. Significant elevation of procalcitonin (PCT) has been described in two adults patients. This study we report two cases of a 14-year-old male and a 13-year-old female with a AHS and a high level of the PCT. These are the first cases described in pediatric age. Establishing a diagnosis of AHS is important to avoid the use of the involved drug. The treatment is based on the withdrawal of the drugs that are supposed and if there is no improvement or a deterioration of the patient, the use of systemic corticosteroids is often useful.


Subject(s)
Anticonvulsants/adverse effects , Calcitonin/blood , Drug Hypersensitivity/diagnosis , Protein Precursors/blood , Adolescent , Calcitonin Gene-Related Peptide , Carbamazepine/adverse effects , Drug Eruptions , Drug Hypersensitivity/blood , Drug Hypersensitivity/complications , Epilepsy, Frontal Lobe/complications , Epilepsy, Frontal Lobe/drug therapy , Epstein-Barr Virus Infections/complications , Female , Humans , Male , Pentobarbital/adverse effects , Phenytoin/adverse effects , Transaminases/blood
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