ABSTRACT
The authors report the infectious complications observed during the treatment of acute lymphoblastic leukemia in 70 children, followed by a same team, with the same protocole, for a period of 6 years (mean follow-up: 42.3 months). The complications were mainly bacterial during induction phase, mainly staphylococcic the microbiological follow-up and a rapid empiric antibiotic therapy allowed to control more than 80% of the febrile episodes. There was one death from fulminant pyocyanic infection.
Subject(s)
Bacterial Infections/etiology , Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy , Adolescent , Anti-Bacterial Agents , Antineoplastic Combined Chemotherapy Protocols/adverse effects , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Bacterial Infections/drug therapy , Child , Child, Preschool , Drug Therapy, Combination/therapeutic use , Female , Follow-Up Studies , Humans , Iatrogenic Disease , Infant , Male , Retrospective Studies , Risk Factors , Virus Diseases/etiologyABSTRACT
About 2 cases reports, the authors stress on the principal characteristics of neurotoxoplasmosis : neurologic and/or febrile symptoms in a immuno-compromised patient with predominantly a deficient cellular mediated immunity. Cerebrospinal fluid, electroencephalographic and tomodensitometric abnormalities. Importance of serology in the survey of high-risk patients. Bad prognosis of acute clinical pictures. Potential regression of subacute and chronic forms.
