ABSTRACT
Erythema elevatum diutinum (EED) is a rare cutaneous neutrophilic vasculitis with many associated diseases reported in the literature. We report a 65-year-old woman with painful and itchy lesions on her elbows, hands, knees, and foot for a year. Histopathologic examination confirmed the diagnosis of erythema elevatum diutinum and treatment with dapsone produced significant clinical improvement within few weeks. Erythema elevatum diutinum is a rare disease that should be considered in patients with violaceous nodular plaques located over the extensor regions of the limbs. Knowledge of this unusual pathology and its association helps to avoid misdiagnosis and late treatment.
Subject(s)
Arthritis, Rheumatoid , Vasculitis, Leukocytoclastic, Cutaneous , Humans , Female , Aged , Vasculitis, Leukocytoclastic, Cutaneous/diagnosis , Vasculitis, Leukocytoclastic, Cutaneous/drug therapy , Vasculitis, Leukocytoclastic, Cutaneous/pathology , Skin/pathology , Dapsone/therapeutic use , Arthritis, Rheumatoid/complications , Arthritis, Rheumatoid/drug therapy , Erythema/pathologyABSTRACT
Psoriasiform Keratosis is a rare clinic entity. The etiopathogenesis remains unknown and the disease is characterized by a solitary, scaly or keratotic papule, or plaque mainly located on the extremities. Histopathological features closely resemble those of psoriasis. We report the case of a 70-year-old woman presenting a solitary and asymptomatic keratotic plaque, located on the back of the left leg, unresponsive to topical corticosteroids. We performed an excisional biopsy and histopathology was consistent with psoriasiform keratosis.
Subject(s)
Keratosis/pathology , Psoriasis/pathology , Aged , Biopsy , Female , Humans , Leg Dermatoses/pathology , Skin/pathologyABSTRACT
Psoriasiform Keratosis is a rare clinic entity. The etiopathogenesis remains unknown and the disease is characterized by a solitary, scaly or keratotic papule, or plaque mainly located on the extremities. Histopathological features closely resemble those of psoriasis. We report the case of a 70-year-old woman presenting a solitary and asymptomatic keratotic plaque, located on the back of the left leg, unresponsive to topical corticosteroids. We performed an excisional biopsy and histopathology was consistent with psoriasiform keratosis.
Subject(s)
Humans , Female , Aged , Psoriasis/pathology , Keratosis/pathology , Skin/pathology , Biopsy , Leg Dermatoses/pathologyABSTRACT
Pyoderma gangrenosum is a rare, inflammatory, chronic and recurrent disease of unknown etiology, characterized by noninfectious, necrotizing and painful cutaneous ulcers. Usually it affects adults aged between 25 and 54 years old and rarely children (less than 4%), in which it mainly affects the head, face, buttocks, genital and perianal region. The disease presents a quick response to systemic corticosteroids. We report a case of a newborn with hemorrhagic and necrotic ulcers, distributed in the abdomen, buttocks and genital region with rapid and effective response to oral prednisone.
Subject(s)
Glucocorticoids/therapeutic use , Prednisone/therapeutic use , Pyoderma Gangrenosum/drug therapy , Pyoderma Gangrenosum/pathology , Chronic Disease , Female , Humans , Infant, Newborn , Skin/pathology , Treatment OutcomeABSTRACT
Pyoderma gangrenosum is a rare, inflammatory, chronic and recurrent disease of unknown etiology, characterized by noninfectious, necrotizing and painful cutaneous ulcers. Usually it affects adults aged between 25 and 54 years old and rarely children (less than 4%), in which it mainly affects the head, face, buttocks, genital and perianal region. The disease presents a quick response to systemic corticosteroids. We report a case of a newborn with hemorrhagic and necrotic ulcers, distributed in the abdomen, buttocks and genital region with rapid and effective response to oral prednisone.
O Pioderma gangrenoso é uma doença inflamatória rara, crônica e recorrente, de etiopatogenia desconhecida, caracterizada por uma ulceração não-infecciosa, necrotizante e dolorosa da pele. Geralmente, afeta adultos na faixa de 25 a 54 anos e raramente crianças (menos de 4%), nestes acomete preferencialmente cabeça e face, nádegas, região perianal e genital. Apresenta rápida resposta à corticoterapia sistêmica. Relata-se um caso de recém-nascida com lesões ulceradas de pioderma gangrenoso de fundo hemorrágico e necrótico distribuídas em abdômen, região genital e glútea com resposta rápida e efetiva à prednisona oral.
Subject(s)
Female , Humans , Infant, Newborn , Glucocorticoids/therapeutic use , Prednisone/therapeutic use , Pyoderma Gangrenosum/drug therapy , Pyoderma Gangrenosum/pathology , Chronic Disease , Skin/pathology , Treatment OutcomeABSTRACT
Investiga a produçäo vocal do bebê como produto que emerge, ao longo do tempo, da dinämica processual das negociaçöes entre os parceiros diádicos. Analisa os registros em video-cassete de uma díade mäe-bebê, durante os primeiros seis meses de vida em situaçäo natural. Estuda duas organizaçöes diádicas: face-a-face e mäe-objeto-bebê. Observa o uso proporcionalmente mais frequente de sons semelhantes a vogais nas organizaçöes face-a-face, näo ocorrendo naquelas mäe-objeto-bebê. Encontra uma relaçäo entre a utilizaçäo proporcionalmente superior do processo de especularidade e o aumento de sons semelhantes a vogais, apenas nas organizaçöes face-a-face. Propöe uma perspectiva teórica e metodológica que considera o desenvolvimento da comunicaçäo como um processo relacional/dialógico que constrói significados partilhados criando o novo. A emergência dos Ss e da própria comunicaçäo resulta desta dinâmica processual
Subject(s)
Infant , Mother-Child Relations , VoiceABSTRACT
Este trabalho investigou a producao vocal do bebe como produto que emerge, ao longo do tempo, da dinamica processual das negociacoes entre os parceiros diadicos. Foram analisados os registros em video-cassete de uma diade mae-bebe, durante os primeiros seis meses de vida do bebe, em situacao natural. Duas organizacoes diadicas foram estudadas: face-a-face e mae-objeto-bebe. O uso proporcionalmente mais frequente de sons semelhantes a vogais foi observado nas organizacoes face-a-face, nao ocorrendo naquelas mae-objeto-bebe. Foi encontrada uma relacao entre a utilizacao proporcionalmente superior do processo de especularidade e o aumento de sons semelhantes a vogais, apenas nas organizacoes face-a-face. E proposta uma perspectiva teorica e metodologica que considera o desenvolvimento da comunicacao como um processo relacional/dialogico que constroi significados partilhados criando o novo. A emergencia dos sujeitos e da propria comunicacao resulta desta dinamica processual.