Revisiting the effects of configuration, predictability, and relevance on visual detection during interocular suppression.

Statistical regularities and predictions can influence the earliest stages of visual processing. Studies examining their effects on detection, however, have yielded inconsistent results. In continuous flash suppression (CFS), where a static image projected to one eye is suppressed by a dynamic image presented to the other, the predictability of the suppressed signal may facilitate or delay detection. To identify the factors that differentiate these outcomes and dissociate the effects of expectation from those of behavioral relevance, we conducted three CFS experiments that addressed confounds related to the use of reaction time measures and complex images. In experiment 1, orientation recognition performance and visibility rates increased when a suppressed line segment completed a partial shape surrounding the CFS patch, demonstrating that valid configuration cues facilitate detection. In Experiment 2, however, predictive cues marginally affected visibility and did not modulate localization performance, challenging existing findings. In experiment 3, a relevance manipulation was introduced; participants pressed a key upon detecting lines of a particular orientation, ignoring the other possible orientation. Visibility and localization were enhanced for relevant orientations. Predictive cues modulated visibility, orientation recognition sensitivity, and response latencies, but not localization-an objective measure sensitive to partial breakthrough. Thus, while a consistent surround can strongly enhance detection during passive observation, predictive cueing primarily affects post-detection factors such as response readiness and recognition confidence. Relevance and predictability did not interact, suggesting that the contributions of these two processes to detection are mostly orthogonal.

Auditory Target Detection Enhances Visual Processing and Hippocampal Functional Connectivity.

Though dividing one's attention between two input streams typically impairs performance, detecting a behaviorally relevant stimulus can sometimes enhance the encoding of unrelated information presented at the same time. Previous research has shown that selection of this kind boosts visual cortical activity and memory for concurrent items. An important unanswered question is whether such effects are reflected in processing quality and functional connectivity in visual regions and in the hippocampus. In this fMRI study, participants were asked to memorize a stream of naturalistic images and press a button only when they heard a predefined target tone (400 or 1,200 Hz, counterbalanced). Images could be presented with a target tone, with a distractor tone, or without a tone. Auditory target detection increased activity throughout the ventral visual cortex but lowered it in the hippocampus. Enhancements in functional connectivity between the ventral visual cortex and the hippocampus were also observed following auditory targets. Multi-voxel pattern classification of image category was more accurate on target tone trials than on distractor and no tone trials in the fusiform gyrus and parahippocampal gyrus. This effect was stronger in visual cortical clusters whose activity was more correlated with the hippocampus on target tone than on distractor tone trials. In agreement with accounts suggesting that subcortical noradrenergic influences play a role in the attentional boost effect, auditory target detection also caused an increase in locus coeruleus activity and phasic pupil responses. These findings outline a network of cortical and subcortical regions that are involved in the selection and processing of information presented at behaviorally relevant moments.

A possible evolutionary function of phenomenal conscious experience of pain.

Evolutionary accounts of feelings, and in particular of negative affect and of pain, assume that creatures that feel and care about the outcomes of their behavior outperform those that do not in terms of their evolutionary fitness. Such accounts, however, can only work if feelings can be shown to contribute to fitness-influencing outcomes. Simply assuming that a learner that feels and cares about outcomes is more strongly motivated than one that does is not enough, if only because motivation can be tied directly to outcomes by incorporating an appropriate reward function, without leaving any apparent role to feelings (as it is done in state-of-the-art engineered systems based on reinforcement learning). Here, we propose a possible mechanism whereby pain contributes to fitness: an actor-critic functional architecture for reinforcement learning, in which pain reflects the costs imposed on actors in their bidding for control, so as to promote honest signaling and ultimately help the system optimize learning and future behavior.

Dynamic Computation in Visual Thalamocortical Networks.

Contemporary neurodynamical frameworks, such as coordination dynamics and winnerless competition, posit that the brain approximates symbolic computation by transitioning between metastable attractive states. This article integrates these accounts with electrophysiological data suggesting that coherent, nested oscillations facilitate information representation and transmission in thalamocortical networks. We review the relationship between criticality, metastability, and representational capacity, outline existing methods for detecting metastable oscillatory patterns in neural time series data, and evaluate plausible spatiotemporal coding schemes based on phase alignment. We then survey the circuitry and the mechanisms underlying the generation of coordinated alpha and gamma rhythms in the primate visual system, with particular emphasis on the pulvinar and its role in biasing visual attention and awareness. To conclude the review, we begin to integrate this perspective with longstanding theories of consciousness and cognition.

Fundamental computational constraints on the time course of perception and action.

A cognitive system faced with contingent events that cause rapid changes in sensory data may (i) incrementally incorporate new data into the ongoing perceptual and motor processing; or (ii) restart processing on each new event; or (iii) sample the data and hold onto the sample until its processing is complete, while disregarding any contingent changes. We offer a set of computational first-principles arguments for a hypothesis, according to which any system that contends with certain classes of perception and behavioral control tasks must include the sample-and-hold option (possibly alongside the other two, which may be useful in other tasks). This hypothesis has implications for understanding the dynamics of perception and action. In particular, a sample-and-hold channel necessarily processes sensory data on some kind of cycle (which does not imply precise periodicity). Further, being prepared to face the world at all times requires that the sampling that initiates each cycle be triggered by every significant action on part of the agent itself, such as saccades. We survey a range of evidence for the sample-and-hold functionality, touching upon diverse phenomena such as attentional blink and backward masking, the yoking of olfaction to respiration, thalamocortical interactions, and metastable brain dynamics in perception and consciousness.