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Eur Arch Otorhinolaryngol ; 276(7): 2039-2045, 2019 Jul.
Article in English | MEDLINE | ID: mdl-31069467

ABSTRACT

PURPOSE: Late-stage OTSCC is associated with poor overall survival (OS). Non-curative treatment approach aims to improve quality of life and prolong survival of patients deemed incurable. The purpose of this study was to investigate the used non-curative treatment modalities for OTSSC and patient survival. METHODS: All patients diagnosed with OTSCC and treated with non-curative intent at the HUS Helsinki University Hospital (Helsinki, Finland) during the 12-year period of 2005-2016 were included. Survival analysis after the non-curative treatment decision was conducted using the Kaplan-Meier method in this population-based study. RESULTS: Eighty-two patients were identified. A non-curative treatment decision was made at presentation without any previous treatment in 26 patients (7% of all patients diagnosed with OTSCC during the study period). Palliative radiotherapy was administered to 24% of all patients. The average survival time after the non-curative treatment decision was 3.7 months (median 2 and range 0-26). CONCLUSIONS: Due to the short mean survival time after decision for treatment with non-curative intent, and the notable symptom burden in this patient population, a prompt initiation of all non-curative measures is warranted.


Subject(s)
Palliative Care , Quality of Life , Squamous Cell Carcinoma of Head and Neck , Tongue Neoplasms , Adult , Aged , Clinical Decision-Making , Female , Finland/epidemiology , Humans , Male , Middle Aged , Neoplasm Staging , Palliative Care/methods , Palliative Care/psychology , Retrospective Studies , Squamous Cell Carcinoma of Head and Neck/mortality , Squamous Cell Carcinoma of Head and Neck/pathology , Squamous Cell Carcinoma of Head and Neck/psychology , Squamous Cell Carcinoma of Head and Neck/therapy , Survival Analysis , Survival Rate , Tongue Neoplasms/mortality , Tongue Neoplasms/pathology , Tongue Neoplasms/psychology , Tongue Neoplasms/therapy
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