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Pol Arch Med Wewn ; 102(5): 973-8, 1999 Nov.
Article in Polish | MEDLINE | ID: mdl-11072532

ABSTRACT

The aim of the study was to estimate the prevelance and distribution of titers of immunoglobulins IgA and IgG reacting with glycine extract of Helicobacter pylori antigens in the group of patients with unstable angina and in the group of symptomless blood donors. The sera of 30 patients and 33 healthy individuals (blood donors) were assessed using ELISA test. Comparing the results from these two groups we observed that distributions of IgG antibodies were not concordant: the higher titers were more typical for the group ++of patients with unstable angina then for blood donors. This suggests that intensive humoral response on H. pylori antigens may play a role in aggravation of symptoms of coronary artery atherosclerosis.


Subject(s)
Angina Pectoris/immunology , Antigens, Bacterial/immunology , Blood Donors , Helicobacter pylori/immunology , Immunoglobulin A/immunology , Immunoglobulin G/immunology , Adult , Coronary Artery Disease/diagnosis , Coronary Artery Disease/immunology , Enzyme-Linked Immunosorbent Assay , Humans , Male , Middle Aged
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