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2.
O.F.I.L ; 32(4): 401-402, 2022. tab
Article in Spanish | IBECS | ID: ibc-212275

ABSTRACT

Se presenta un caso de un paciente diagnosticado de leucemia aguda linfoblástica Pro-T, que se trata con altas dosis de metotrexato. Se describe el manejo de niveles tóxicos de metotrexato que resulta de la colaboración entre el farmacéutico de hospital y el hematólogo. (AU)


We present a case of a patient diagnosed with acute Pro-T lymphoblastic leukemia, who is treated with high doses of methotrexate. The management of toxic levels of methotrexate resulting from the collaboration between the hospital pharmacist and the hematologist is described. (AU)


Subject(s)
Humans , Male , Adult , Methotrexate , Pharmacokinetics , Folic Acid , Neoplasms
3.
O.F.I.L ; 32(4): 407-409, 2022. tab
Article in Spanish | IBECS | ID: ibc-212277

ABSTRACT

El síndrome de lisis tumoral (SLT) es una complicación potencialmente mortal caracterizada por una lisis masiva de células tumorales. A continuación, se presenta el caso de un varón de 28 años, diagnosticado de linfoma no Hodking de células B de alto grado. Este presentó un SLT tras la administración de la quimioterapia, de especial interés debido a las recomendaciones farmacológicas propuestas desde el Servicio de Farmacia en cuanto a la dosis de rasburicasa y las interacciones a nivel electrolítico con la medicación concomitante prescrita durante el ingreso. (AU)


Tumor lysis syndrome (TLS) is a life-threatening complication characterized by a massive lysis of tumor cells. The following is the case of a 28-year-old man diagnosed with high-grade B-cell non-Hodking lymphoma. The patient presented a TLS after the administration of chemotherapy. This case is of special interest due to the pharmaco logical recommendations proposed by the Pharmacy Service regarding the rasburicasa dose and the interactions at the electrolyte level with the concomitant medication prescribed during admission. (AU)


Subject(s)
Humans , Male , Adult , Lymphoma , Drug Therapy , Therapeutics , Patients , Diagnosis
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