ABSTRACT
Chromatophoromas are neoplasms arising from pigment-bearing cells (chromatophores) of the dermis. While isolated cases have been reported in the literature, the prevalence and biological behavior of chromatophoromas in snakes are unknown. Forty-two chromatophoromas were identified among 4663 submissions (0.9%) to a private diagnostic laboratory in a 16-year period. The most commonly affected snakes were colubrids (23 cases, 55%) and vipers (8 cases, 19%). The San Francisco garter snake was the most commonly affected species (6 cases; 14% of all affected snake species and 3.7% of all garter snake submissions). No sex predilection was found. The age of 28 snakes ranged from 5 to 27 years. Single cutaneous chromatophoromas were most commonly observed and presented as pigmented cutaneous masses or plaques along any body segment. Euthanasia or death due to progressive neoplastic disease or metastasis was reported in 8 (19%) and 4 (10%) cases, respectively. The survival time of 4 animals ranged from 4 to 36 months. Microscopically, xanthophoromas, iridophoromas, melanocytic neoplasms, and mixed chromatophoromas were identified, with melanocytic neoplasms being most common. Microscopic examination alone was generally sufficient for the diagnosis of chromatophoroma, but immunohistochemistry for S-100 and PNL-2 may be helpful for diagnosing poorly pigmented cases. Moderate to marked nuclear atypia appears to be consistently present in cutaneous chromatophoromas with a high risk of metastasis, while mitotic count, lymphatic invasion, the level of infiltration, and the degree of pigmentation or ulceration were not reliable predictors of metastasis.
Subject(s)
Chromatophores/pathology , Skin Neoplasms/veterinary , Snakes , Animals , Animals, Zoo , Colubridae , Female , Male , Skin/pathology , Skin Neoplasms/diagnosis , Skin Neoplasms/pathology , ViperidaeABSTRACT
Paciente femenino de 27 años, que posteriormente atrauma en región escapular izquierda, nota un crecimientoen la zona, con dolor y limitación de movimiento. En laresección parcial se diagnostica como condrosarcomamesenquimal extraesquelético. Se procede a quimioterapianeoadyuvante con 5 ciclos. Hubo reducción del tumor primarioun 30%. Se efectúa tratamiento quirúrgico (tumor de10 × 9 × 5 cm, bordes libres) y se suministran dos ciclosmás de quimioterapia, sin respuesta, evolucionando laenfermedad y falleciendo. Este tipo de sarcomas son agresivoscon altas recurrencias locales y metástasis, más frecuentementea pulmón y a hueso(AU)
A 27 year old woman developed a painful swelling inthe left scapular region accompanied by a limitation inmovement following trauma. She underwent partial resectionof the mass which was diagnosed histologically as anextraskeletal mesenchymal chondrosarcoma. She was treatedwith 5 cycles of neoadjuvant chemotherapy which reducedthe primary tumour by 30% and the metastases by 60%.Subsequently, a three dimensional resection was carried outand a 10 × 9 × 5 cm tumour with free edges was removed.She was treated with a further 2 cycles of adjuvant chemotherapy,but with no response, after which she died. Thisaggressive type of sarcomas has a high risk of both localrecurrence and metastases, predominately to the lungs andbones(AU)
Subject(s)
Humans , Female , Adult , Chondrosarcoma, Mesenchymal/diagnosis , Chondrosarcoma, Mesenchymal/pathology , Neoadjuvant Therapy/methods , Neoadjuvant Therapy , Immunohistochemistry/methods , Diagnosis, Differential , Prognosis , Chondrosarcoma, Mesenchymal/immunology , Cytogenetics/methods , Cytogenetics/trendsABSTRACT
Entre los subtipos de carcinomas indiferenciados de células grandes de pulmón se encuentra el linfoepitelioma pulmonar primario. Es una variedad de neoplasia pulmonar muy infrecuente. Su diagnóstico obliga de forma sistemática a descartarque se trate de una metástasis de un tumor primario nasofaríngeo. La cirugía es el tratamiento de elección. Aún no están totalmente establecidas las indicaciones y los regímenes ideales de quimioterapia y radioterapia. Dar a conocer la experiencia de los casos diagnosticados ayudará a conocer más sobre el comportamiento de estos tumores
Lymphoepithelioma-like carcinoma of the lung (LELC) is considered a subtype of undifferentiated large cell carcinoma. It´s a rare tumor. It is imperative that a nasopharynx origin is actively excluded in all cases. The choice treatment is surgical resection. Experience with systematic chemotherapy or radiotherapy in the treatment of LELC is limited
Subject(s)
Humans , Male , Aged , Carcinoma, Non-Small-Cell Lung/pathology , Lung Neoplasms/pathology , PneumonectomySubject(s)
Duodenal Diseases/etiology , Helicobacter Infections/etiology , Helicobacter pylori , Stomach Diseases/etiology , Anti-Bacterial Agents , Drug Therapy, Combination/therapeutic use , Duodenal Diseases/diagnosis , Duodenal Diseases/drug therapy , Helicobacter Infections/diagnosis , Helicobacter Infections/drug therapy , Humans , Stomach Diseases/diagnosis , Stomach Diseases/drug therapyABSTRACT
BACKGROUND: To evaluate nursing practice in periodic health examination. METHODS: We make a retrospective evaluation of process data through 10 explicit criteria. We selected a random sample (in evaluation process) and a institutional based sample and population universe (re-evaluation process) of both male and female patients who underwent health examination in nursing consults of a urban health center. RESULTS: We found a substantial improvement in fulfilling degree in 8 out of criteria, although best standard only was reached in 3 criteria (blood pressure determination, somatometrics and tobacco smoking investigation). We also remark the high proportion of risk factors, tobacco smoking (51.6%), obesity (37.6%) and dyslipemia (25.5%). CONCLUSIONS: We remark the importance of entering and developing evaluation and quality assurance methodology among common tasks of primary care teams and correct ubication of periodic health examination in nursing process.
Subject(s)
Health Promotion , Physical Examination , Preventive Medicine , Primary Health Care , Quality of Health Care , Adolescent , Adult , Aged , Aged, 80 and over , Child , Child, Preschool , Female , Health Services , Humans , Hypertension/prevention & control , Male , Middle Aged , Obesity/prevention & control , Quality Assurance, Health Care , Smoking Prevention , Spain , Urban PopulationABSTRACT
The slipping rib syndrome can be produced by a direct or indirect traumatism over the sternal tip of the costal cartilages 8, 9 and 10. The main complains are abdominal pain in the right or left upper abdominal, quadrants, and sometimes a sensation of rubbing or slipping of the ribs. The hoocking maneuver is useful in the diagnosis of this syndrome. Three clinical cases of the slipping rib syndrome are reported. This syndrome must be taken into account is the differential diagnosis of the abdominal pain in pediatric patients.
