[Dynamics and structure of the neonatal mortality in Kutaisi and Imereti region].

Dynamics of neonatal mortality and analysis of its structure in Kutaisi and in the region of Imereti during 1999-2000 are presented. Insufficiency in the organization of the prophylactic and treatment measures during the pregnancy and delivery and mistakes in the treatment, were determined according to the analyses of expert cards. Data of the State Department of Statistics and statistical counting of the labor houses and labor-helping setting of Kutaisi also were used. Analysis of the collected data shows high rates of perinatal and neonatal mortality in Kutaisi and birth reduction. However some trends in the reduction of these findings were occurred in the year 1996, which could be explained by the aids in the delivery blocks in the labor houses of Kutaisi.

[Immunologic indicators in mothers of low birth weight infants]. / Immunologicheskie pokazateli materei novorozhdennykh s nizkoi massoi tela pri rozhdenii.

Neutrophil function, circulating immune complexes, major immunoglobulins and lysozyme activity have been determined in mothers of 86 newborns, of whom 24 were term infants with normal birthweight, 27 had first-degree prematurity and 35 were term newborns with low-birth weight. The mothers of premature newborns showed prominent impairment of bactericidal properties and functional stores of neutrophilic phagocytes, while mothers of term newborns with low-birth weight had abnormalities of humoral immunity.

[Circulating immune complexes and neutrophil function in low-birth-weight newborn infants in the early neonatal period]. / Tsirkuliruiushchie immunnye kompleksy i funktsional'naia aktivnost' neitrofilov u novorozhdennykh s nizkoi massoi tela v rannem neonatal'nom periode.

Peripheral blood neutrophil function and the content of circulating immune complexes in funic blood were examined in 35 premature neonates with low body weight, 27 neonates with grade I prematurity and in 24 normal full-term neonates (a control group) by days 1-2 and days 7-8 of life. The positive time-course of changes in the neutrophil capacity for completed phagocytosis and in the content of circulating immune complexes was disclosed in full-term neonates with low body weight at birth. The same parameters showed a negative time-course of changes in premature neonates.

[Brain histology of premature infants who have suffered hypoxia and sepsis]. / K gistologii golovnogo mozga nedonoshennykh detei, perenesshikh gipoksiiu i sepsis.

Results of brain studies in 38 premature infants with severe peri- and postnatal pathology (intracranial labor trauma, asphyxia, sepsis) are presented. Clinico-morphological data detected that profound prematurity and consequently a profound immaturity of the brain, complicated by hypoxic damages during labor and early developing septic infections, lead to an expressed retardation and irreversible degenerative changes, especially in the brain structures which develop later. From the neurological point of view the most serious in relation to the prognosis are those children who are in a state of a stable inhibition of the CNS.

[Reactions of premature children suffering intracranial birth injury to color stimuli]. / Osobennosti reaktsii na tsvetovye razdrazhiteli u nedonoshennykh detei, perenesshikh vnutricherepnuiu rodovuiu travmu

The dynamics of formation of integrated reactions to colour stimuli is substantially disturbed in babies of the first three months of life. Stable disturbances in the development of reactions by EEG and somato-vegetative components parameters, accompanied by changes of the neurological status in children with severe symptoms of intracranial delivery trauma, testify to a profound and stable disturbance of the CNS functions and to a change in cortico-subcortical relationships, possibly in connection with an organic lesion of the brain. In the case of a less severe trauma, the dinamics of the formation of reactions is normalized prior to the improvement of the clinical state and is a good prognostic phenomenon. In the light of published data, changes in the vegetative components of reactions in traumatized babies are regarded as resulting from compensatory reactions of the hypothalamic structures to hypoxia.