1.
Cardiology
; 66 Suppl 2: 85-93, 1980.
Article
in Spanish
| MEDLINE
| ID: mdl-6116543
Subject(s)
Blood Pressure/drug effects , Epinephrine/blood , Heart Rate/drug effects , Hypertension/drug therapy , Norepinephrine/blood , Phenoxybenzamine/pharmacology , Prazosin/pharmacology , Quinazolines/pharmacology , Adrenergic alpha-Antagonists/pharmacology , Adult , Clinical Trials as Topic , Double-Blind Method , Female , Humans , Male , Middle Aged , Random Allocation
2.
J Cardiovasc Pharmacol
; 1(6 Suppl): S1-7, 1979.
Article
in English
| MEDLINE
| ID: mdl-94635
Subject(s)
Blood Pressure/drug effects , Catecholamines/blood , Heart Rate/drug effects , Hypertension/physiopathology , Phenoxybenzamine/pharmacology , Prazosin/pharmacology , Quinazolines/pharmacology , Adult , Body Weight , Female , Humans , Hypertension/blood , Male , Middle Aged , Phenoxybenzamine/adverse effects , Prazosin/adverse effects , Time Factors
3.
Clin Pharmacol Ther
; 26(4): 437-41, 1979 Oct.
Article
in English
| MEDLINE
| ID: mdl-487690
ABSTRACT
Azosemide is a new loop diuretic which has been shown to affect solute transport proximal to the diluting segment. We assessed the effects of chronic administration of azosemide in normal subjects on low and normal salt diets. In both, there was compensatory renin release and aldosterone secretion, but the subjects on the low sodium diet developed striking hyperuricemia and metabolic alkalosis and were symptomatic, whereas those on the normal diet compensated to the extent that there were only minor changes.
