ABSTRACT
Dye effluents discharged from various industries contribute to environmental contamination, making their treatment highly necessary. Infectious diseases also pose a threat to public health worldwide. Nanomaterials have promising features and are potential candidates for overcoming the problems of drug resistance in microbes and environmental pollution. Therefore, this study aimed to synthesize zinc oxide (ZnO) and magnesium-doped zinc oxide (Mg-doped ZnO) nanoparticles (NPs) using the plant extract of Lupinus albus for applications in photocatalysis and antimicrobial activity. A sample of Lupinus albus leaves was collected from Motta, in the eastern Gojjam zone of Ethiopia. The leaves were air-dried and then ground into a powder. The powdered plant material was extracted using distilled water. The ZnO and Mg-doped ZnO NPs were synthesized using 0.1 M Zn(NO3)2·6H2O, 7.5% 0.1 M Mg(NO3)2.6H2O, and 10 mL of the leaf extract. The nanoparticles (NPs) were characterized using UV-vis, FT-IR, XRD, and SEM. The average crystallite sizes of ZnO and Mg-doped ZnO NPs were determined using the Debye-Scherrer formula and were found to be 28.1 and 34.4 nm, respectively. The antimicrobial activity of the synthesized NPs was evaluated against four bacterial strains (Escherichia coli, Bacillus cereus, Salmonella typhi, and Staphylococcus aureus) and one fungal strain (Candida albicans) by using the agar disk diffusion method. The Mg-doped ZnO NPs exhibited significant antimicrobial activity, with a maximum zone of inhibition measuring 24 and 22 mm against Escherichia coli and Salmonella typhi, respectively. The photocatalytic activity of ZnO and Mg-doped ZnO NPs was investigated by studying the degradation of methylene blue (MB) dye under sunlight irradiation for 120 min. The results showed that Mg-doped ZnO NPs exhibited higher photocatalytic activity (99.6%) than ZnO NPs (94.1%). In conclusion, the synthesized NPs could serve as viable alternatives for antimicrobial drugs and photocatalysts to mitigate the pollution of the environment caused by organic dyes.
ABSTRACT
BACKGROUND: Preterm birth infants are at a greater risk of mortality and a variety of health and developmental problems; reliable data support that this rate is increasing in almost all countries. The purpose is to find the magnitude of preterm birth and its associated factors among newborns delivered at Butajira Hospital, Southern Nations, Nationalities, and People's Region, Ethiopia. METHODS: This hospital-based cross-sectional study was carried out on 304 maternity cards using the systematic sampling method during May 1_21 in 2019. The data collection was performed using a structured case record form. The data were entered into EpiData software (version 3.1) and analyzed using SPSS software (version 21). Binary and multivariable logistic regression analyses were computed to identify the associated factors at 95% CI. RESULTS: Overall magnitude of preterm birth was observed to be 15.5%. The factors significantly associated with the preterm birth were preeclampsia (AOR = 4.0; 95% CI: 1.6-10.0), and premature rupture of fetal membranes (AOR = 4.2; 95% CI: 1.4-12.9). CONCLUSION: Preterm birth is still public concern in the study area. The concerned administrative body should implement health education programs and improve the quality of health care delivered to pregnant mothers to control these associated factors and, consequently, promote public health in the study area.
