[Influence of modern dental materials on the oral mucosa]. / Vliyanie sovremennykh stomatologicheskikh materialov na slizistuyu obolochku polosti rta.

This article provides the current data of the modern literature on the question of the biocompatibility of dental materials, their influence on the local immune homeostasis of the oral cavity; influence of the method of transmission of masticatory load on the tissues and organs of the oral cavity. Thus, when installing the seal, the choice of material, the localization of carious lesions, and when prosthetics - the choice of material of the prosthetic structure and the method of transfer of chewing load is important. It should be understood that the reaction of the mucous membrane can be not only in the area of direct contact with the dental material, but also appear in remote areas of the oral mucosa.

[The influence of dental status on local immunity of oral cavity of elderly and senile patients with squamous cell carcinoma of the oral cavity mucosa.]

This article presents the results of a study of the dental status of 60 elderly and senile patients with squamous cell carcinoma of the oral mucosa. The use of removable and non-removable dentures, carious lesions of teeth, dental plaque, sharp edges of the crown seals were studied as components of the dental status.

[Dental status as a predictive factor in the development of squamous cell carcinoma of the oral mucosa]. / Stomatologicheskii status kak prognosticheskii faktor razvitiia ploskokletochnogo raka slizistoi obolochki polosti rta.

The aim of this work was to study the influence of components of dental status on the local immunity of the oral cavity; we compared the results of the study of patients with squamous cell carcinoma (SCC) of the oral mucosa and patients without neoplasm. The study involved 136 patients with squamous cell carcinoma of the oral mucosa and 57 patients without neoplasms. In the role of the constituent characteristics of dental status were examined: the use of removable and fixed dentures, dental caries, dental plaque, sharp edges of fullings. Matrix metalloproteinases (MMPs) 2, 8 and 9, as well as their tissue inhibitors 1 and 2 were assessed in oral fluid. The results suggest the influence of all factors on local immune status of the oral cavity as proved by the significant changes in MMPs level. The use of removable dentures resulted in the pronounced decrease of MMPs and should be considered in oral SSC screening and non-invasive diagnostics.