ABSTRACT
Size tunability of thiophenol capped CdS nanoparticles (NPs) has been achieved by controlling the temperatures in situ. Synthesis at 5 degrees C produced stable particles of smallest size having narrow size distribution and high photoluminescence quantum yield. The photoluminescence of thiophenol capped CdS NPs was quenched by the nitroaromatic compounds. The Stern-Volmer constant of dinitrobenzene was about 15-fold higher than nitrobenzene, which indicates that introduction of nitro groups in the benzene ring increases the quenching efficiency. Further, the as-prepared CdS NPs were found to display size dependent photocatalytic activity towards degradation of nitroaromatics. The catalytic efficiency of CdS quantum particles was quintupled with decrease in particle size from 5.8 to 3.8 nm. An empirical equation has been derived to correlate the catalytic efficiency of the nanoparticles with the twin factors operating in the quantum confinement regime: (i) change in surface to volume ratio and (ii) shift in conduction band edge.
ABSTRACT
The antineoplastic activity of a platinum complex K4 (Pt Cl2 ATP) (Pt-ATP) has been investigated in transplantable tumors, both in an ascitic and solid (Ehrlich ascites carcinoma) tumor model. It has been observed that the drug at the total dose of 10 mg/kg body weight successfully inhibited the tumor burden both in ascitic and solid tumor system and subsequently increased the host's life span. An assessment of the in vitro (3H) thymidine incorporation into TCA precipitable material of EAC tumor cells done in the presence of Pt-ATP indicates that the drug inhibits (3H) thymidine incorporation in tumor cells. The drug has no appreciable toxic effect on the peripheral blood cells as well as bone marrow and spleenic cellularity.
