1.
Org Lett
; 5(18): 3285-8, 2003 Sep 04.
Article
in English
| MEDLINE
| ID: mdl-12943408
ABSTRACT
[reaction: see text] Ligand-free Pd(OAc)(2) can be used as a catalyst in the Heck reaction of aryl bromides as long as the amount of catalyst is kept between 0.01 and 0.1 mol %. At higher concentrations palladium black forms and the reaction stops. The actual catalyst is monomeric. Palladacycles merely serve as a source of ligand-free palladium in Heck reactions of aryl bromides.