1.
J Antimicrob Chemother
; 64(4): 875-7, 2009 Oct.
Article
in English
| MEDLINE
| ID: mdl-19671587
Subject(s)
Antiviral Agents/pharmacology , Drug Resistance, Viral , Guanine/analogs & derivatives , Hepatitis B/drug therapy , Hepatitis B/virology , Lamivudine/pharmacology , Mutation, Missense , Adult , Amino Acid Sequence , Antiviral Agents/therapeutic use , Guanine/pharmacology , Guanine/therapeutic use , Humans , Male , Molecular Sequence Data , Selection, Genetic , Treatment Outcome
2.
AIDS
; 19(16): 1916-9, 2005 Nov 04.
Article
in English
| MEDLINE
| ID: mdl-16227803
ABSTRACT
The vast majority of HIV-1 infections globally are caused by subtype A or C, although little is known about their drug resistance profiles. We found that HAART-experienced patients infected with subtype A had a lower prevalence of K65R and Y181C than those with subtypes B or C, despite similar exposure to antiretroviral agents that select for these mutations. If confirmed, this information may be important in the planning of antiretroviral regimens in patients infected with HIV-1 subtype A.
