ABSTRACT
INTRODUCTION: Prostate cancer (PCa) is the second most common male cancer in the world. Its incidence is estimated to grow to 1.7 million new cases and 499,000 new deaths by 2030. Treatment of OCPC can affect patients physically and mentally, as well as their close relationships and their job or career, which conditions health-related quality of life (QoL). OBJECTIVE: Evaluate the impact on QoL attributable to the treatment for Organ Confined Prostate Cancer (OCPC). MATERIALS AND METHODS: Prospective multicenter observational study of 406 patients with OCPC treated from January 2015 to June 2018. The sample was divided into four study groups, according to the type of treatment: radical prostatectomy (RP) (GA), external radiotherapy (ERT) (GB), brachytherapy (BT) (GC) and other treatments different from monotherapy with RP, ERT or BT (GD). RESULTS: The age in GC was lower, the mean Prostate Specific Antigen (PSA) of all patients was 8.13 ng/ml, the group with the highest mean PSA was GB with a mean of 10.43 ng/dL, the mean Tumor Stage (TNM) was 3.82, and GD had the lowest post treatment quality of life. CONCLUSION: OCPC treatment affects QoL. Curative monotherapies, specifically RP and BT, have less effect on QoL than external radiotherapy or other therapeutic alternatives. Urinary incontinence and fistulas secondary to OCPC have the highest impact on QOL impairment. The internationally validated SF 36 questionnaire is a useful cross-sectional measure of QOL to compare the impact of OCPC treatment modalities.
Subject(s)
Prostatic Neoplasms/therapy , Quality of Life , Aged , Humans , Male , Middle Aged , Prospective Studies , Prostatic Neoplasms/pathologyABSTRACT
Adrenal Pseudocyst are uncommon and asymptomatic tumors. We report an unusual case who had previous high blood pressure and acute hemorrhage presented with abdominal pain and shock. Diagnosis was made with ultrasonography and computed tomography revealed the presence of large retroperitoneal hematoma around the superior pole of the left kidney. Urgent surgery was made with a complete excision of a 10 cm. tumor with preservation of adrenal tissue and the left kidney. Histopathological diagnosis was: Adrenal Pseudocyst. Blood pressure normalized after surgery.
Subject(s)
Adrenal Gland Diseases/diagnosis , Cysts/diagnosis , Abdomen, Acute/etiology , Adrenal Gland Diseases/complications , Adrenal Gland Diseases/surgery , Aged , Cysts/complications , Cysts/surgery , Female , Hematoma/etiology , Humans , Hypertension/etiology , Retroperitoneal Space , Shock/etiologyABSTRACT
Los pseudoquistes suprarrenales son lesiones muy poco frecuentes y asintomáticas. Se describe un caso de presentación inusual caracterizado por hipertensión arterial previa y sangrado agudo espontáneo manifestado por dolor abdominal y shock. El diagnóstico se realizó por medio de Ecografía y Tomografía computarizada, las cuales demostraron la presencia de un hematoma retroperitoneal importante alrededor de una lesión situada en el polo superior del riñón izquierdo. Se realizó intervención quirúrgica de urgencia con resección completa de la lesión de aproximadamente 10 cm. De diámetro preservando parte del tejido suprarrenal y el riñón izquierdo. El diagnóstico anatomopatológico fue: pseudoquiste suprarrenal. Las cifras tensionales se normalizaron después de la cirugía (AU)
Adrenal Pseudocyst are uncommon and asymptomatic tumors. We report an unusual case who had previous high blood pressure and acute hemorrhage presented with abdominal pain and shock. Diagnosis was made with ultrasonography and computed tomography revealed the presence of large retroperitoneal hematoma around the superior pole of the left kidney. Urgent surgery was made with a complete excision of a 10 cm. tumor with preservation of adrenal tissue and the left kidney. Hystopathological diagnosis was: Adrenal Pseudocyst. Blood pressure normalized after surgery (AU)
