The Role of C-Reactive Protein and White Blood Cell Count as Diagnostic, Prognostic, and Monitoring Markers in Bacterial Orofacial Infections.

PURPOSE: 1) To assess the efficacy of C reactive protein (CRP) and white blood cell count (WBC) levels as diagnostic, prognostic, and monitoring tools for determining the severity of bacterial orofacial infections, length of hospital stay (LOS), and the effectiveness of treatment. 2) To evaluate the sensitivity and specificity of CRP and WBC as inflammatory markers in bacterial orofacial infections. METHODS: This prospective study included 30 patients. The predictor variables were serial readings of CRP and WBC that were correlated with clinical course of orofacial infection including severity of infection, length of hospital stay, and effectiveness of treatment. P value was set at (<.05). RESULTS: The sample was composed of 30 patients with a mean age of 26.7 years, 47% female. Predrainage CRP and WBC were significantly positive in predicting severity of infection and length of hospital stay. Predrainage CRP readings were elevated in 93% of patients whereas WBC predrainage readings were elevated in only 56% of patients with orofacial infections. Sensitivity and specificity of CRP are 87.5 and 68%, respectively while sensitivity and specificity of WBC are 62.6 and 86.4%, respectively. CONCLUSION: The results of this study suggest that CRP and WBC are useful diagnostic, prognostic, and monitoring tools in bacterial orofacial infections, with CRP being more sensitive than WBC.

Evaluation of immediate phase of management of missile injuries affecting maxillofacial region in iraq.

In the past two years Iraq was, and still is, subjecting to a confluence of conventional war, civil unrest, guerrilla and terrorist attacks as well as an increasing crime rates. This study evaluates the immediate phase of management of 100 patients suffering from missile injuries to the maxillofacial region. Patients were treated in the maxillofacial unit in the Specialized Surgeries Hospital Medical City, Baghdad during one year (from 2003 to 2004). We had 79 men and 21 women. Age ranged from three to 72 years (mean 37.5 years). The majority of injuries were caused by rifle bullets (49%) followed by fragments (29%), handgun bullets (15%), airgun pellets (6%), and shotgun (1%). Injuries consisted mainly of mandibular fractures found in 56 patients. Urgent airway management was needed in (27%) of patients. Nineteen patients were presented with active bleeding which would not stop without intervention. Most entrance and exit wounds as well as retained missiles were located in the cheek (54.8%, 39.4%, and 27.5% respectively). There were three mortalities due to complications related to head injury. Distribution of missiles used in any conflict reflects the type of this conflict, the prevailing local conditions, and the technological efficiency of weapons used by the opposing teams. Particularly challenging are missile injuries that involve the face, not only because of problems with reconstructing bone and soft tissue defects but also because of emergent problems with airway obstruction and neurovascular compromise.