Tecnología de asistencia para la inclusión educativa de personas con parálisis cerebral: una revisión crítica de la literatura / Assistive technology for the inclusive education of people with cerebral palsy: A critical review of the literature

Introducción. El objetivo fue realizar una revisión crítica, profunda y actualizada de la literatura sobre la tecnología de asistencia para la educación inclusiva de personas con parálisis cerebral. Material y métodos. Se realizó una búsqueda en las bases de datos Scielo, Pubmed y Ebsco del año 2005 a la fecha, tomando como referencia textos completos tanto en inglés como en español. Resultados. Se encontraron 120 documentos de los cuales se seleccionaron 46 tras su análisis crítico, por contener los aspectos más relevantes sobre el tema revisado. Conclusiones. El desconocimiento y ausencia de tecnología de asistencia en las aulas de clase limita el desempeño significativo de las personas con parálisis cerebral en las áreas de educación, comunicación, autocuidado y movilidad que garantizan su participación en el ambiente, en un marco de derechos y deberes para el cumplimiento de las normas establecidas por la ley (AU)

Introduction. This article aims to provide a critical, in-depth and updated review of the literature on assistive technology for the inclusive education of people with cerebral palsy. Material and methods. We searched the Scielo, Pubmed and Ebsco databases from 2005 to the present date, taking as a reference point all full-text publications in English and in Spanish. Results. We found 120 documents, of which 46 were selected after a critical analysis because they discussed the most important aspects on the topic. Conclusions. Lack of knowledge on assistive technology and its absence in the classroom significantly limits the performance of people with cerebral palsy in the areas of education, communication, self-care and mobility. These areas are essential to their participation in the environment within a framework of rights and duties to fulfil the standards set by law (AU)

Rationale and design of ACTIVE: The atrial fibrillation clopidogrel trial with irbesartan for prevention of vascular events / Rationale and design of ACTIVE: The atrial fibrillation clopidogrel trial with irbesartan for prevention of vascular events

Background Atrial fibrillation (AF) is the most frequently occurring cardiac arrhythmia with often serious clinical consequences. Many patients have contraindications to anticoagulation, and it is often underused in clinical practice. The addition of clopidogrel to aspirin (ASA) has been shown to reduce vascular events in a number of high-risk populations. Irbesartan is an angiotensin receptor–blocking agent that reduces blood pressure and has other vascular protective effects. Methods and Results ACTIVE W is a noninferiority trial of clopidogrel plus ASA versus oral anticoagulation in patients with AF and at least 1 risk factor for stroke. ACTIVE A is a double-blind, placebo-controlled trial of clopidogrel in patients with AF and with at least 1 risk factor for stroke who receive ASA because they have a contraindication for oral anticoagulation or because they are unwilling to take an oral anticoagulant. ACTIVE I is a partial factorial, double-blind, placebo-controlled trial of irbesartan in patients participating in ACTIVE A or ACTIVE W. The primary outcomes of these studies are composites of vascular events. A total of 14000 patients will be enrolled in these trials. Conclusions ACTIVE is the largest trial yet conducted in AF. Its results will lead to a new understanding of the role of combined antiplatelet therapy and the role of blood pressure lowering with an angiotensin II receptor blocker in patients with AF.