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J Clin Neurosci ; 18(4): 451-7, 2011 Apr.
Article in English | MEDLINE | ID: mdl-21316970

ABSTRACT

Craniopharyngioma accounts for approximately 1.2% to 4.6% of all intracranial tumours. Their close proximity to vital structures such as the hypothalamic-pituitary axis and optic apparatus makes them one of the most challenging and controversial management dilemmas in neurosurgery. Recurrence following initial transcranial resection is reported as 9% to 51% at a median time of 26 months to 96 months. Treatment options for recurrent craniopharyngioma include repeat surgery, radiotherapy, radiosurgery and intracystic therapies. We present a series of 54 recurrent craniopharyngiomas treated at The Royal Melbourne Hospital between 1991 and 2008 and discuss the management options now available.


Subject(s)
Craniopharyngioma , Neoplasm Recurrence, Local , Pituitary Neoplasms , Adolescent , Adult , Aged , Antineoplastic Agents , Combined Modality Therapy , Craniopharyngioma/epidemiology , Craniopharyngioma/pathology , Craniopharyngioma/therapy , Female , Humans , Incidence , Male , Middle Aged , Neoplasm Recurrence, Local/epidemiology , Neoplasm Recurrence, Local/pathology , Neoplasm Recurrence, Local/therapy , Neurosurgical Procedures , Pituitary Neoplasms/epidemiology , Pituitary Neoplasms/pathology , Pituitary Neoplasms/therapy , Radiotherapy , Young Adult
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