ABSTRACT
PURPOSE: Most infantile periocular hemangiomas undergo rapid growth in the first year of life, followed by gradual resolution over years. Treatment is indicated if vision is compromised and is usually continued through the growth phase. The objective of this study was to determine which clinical characteristics might aid in the prediction of growth and/or regression patterns of periocular hemangiomas. METHODS: Retrospective review of medical records and photographs of children with periocular hemangiomas presenting to a UK pediatric eye unit over a 7-year period. Age at presentation, growth pattern, size, location, amblyopia, and refractive status were documented. RESULTS: Forty-two infants with periocular hemangiomas were evaluated between 2000 and 2007, with a mean follow-up of 24 months (range, 6 months to 5 years). One-third (n=14, 33%) of the hemangiomas were superficial (strawberry nevi); one-third were subcutaneous (n=13, 31%), and the remainder were mixed (n=8, 19%) and orbital (n=7, 17%). There was a marked difference between the growth patterns of superficial (strawberry nevi) and deeper hemangiomas (orbital and subcutaneous), with a more prolonged period of growth noted in the deeper hemangiomas. CONCLUSIONS: Periocular hemangiomas with a deep component tend to have a later onset and prolonged period of growth compared to strawberry nevi. Clinically evident depth of the hemangioma appears to be a valuable predictor of rapidity of resolution. This finding may be useful in assessing prognosis and planning treatment of infantile periocular hemangiomas.
Subject(s)
Hemangioma, Capillary/physiopathology , Neoplasm Regression, Spontaneous/physiopathology , Orbital Neoplasms/physiopathology , Skin Neoplasms/physiopathology , Age of Onset , Amblyopia/physiopathology , Child, Preschool , Female , Follow-Up Studies , Humans , Infant , Infant, Newborn , Male , Refraction, Ocular/physiology , Retrospective StudiesABSTRACT
Erythema multiforme may be a mild condition (erythema multiforme minor), or it may be a severe, possibly life-threatening condition (erythema multiforme major or Stevens-Johnson syndrome). Dorzolamide is a carbonic anhydrase inhibitor, which reduces intraocular pressure by suppressing aqueous production. In this paper we report on a patient who developed erythema multiforme following the use of topical dorzolamide.
Subject(s)
Carbonic Anhydrase Inhibitors/adverse effects , Erythema Multiforme/chemically induced , Glaucoma/drug therapy , Sulfonamides/adverse effects , Thiophenes/adverse effects , Administration, Topical , Aged, 80 and over , Anti-Inflammatory Agents/therapeutic use , Carbonic Anhydrase Inhibitors/administration & dosage , Carbonic Anhydrase Inhibitors/therapeutic use , Cataract Extraction , Drug Eruptions/etiology , Erythema Multiforme/drug therapy , Female , Glaucoma/complications , Humans , Hydrocortisone/therapeutic use , Sulfonamides/administration & dosage , Sulfonamides/therapeutic use , Thiophenes/administration & dosage , Thiophenes/therapeutic use , Visual AcuitySubject(s)
Orbital Cellulitis/microbiology , Staphylococcus aureus/isolation & purification , Streptococcus/isolation & purification , Abscess/microbiology , Adolescent , Child , Child, Preschool , Female , Humans , Infant , Male , Retrospective Studies , Streptococcus pneumoniae/isolation & purification , United KingdomABSTRACT
We report a complication that occurred during clear corneal phacoemulsification. When saline was injected during hydrodissection with a 27-gauge J-shaped cannula attached to a 2.0 mL luer-lock polypropylene syringe, the cannula dislodged and slipped behind the iris, hooking to the lens equator. Although the cannula was carefully removed, 3 clock hours of zonular dialysis were observed between the 4 o'clock and 7 o'clock meridians. After phacoemulsification, lens aspiration, and in-the-bag intraocular lens implantation, vitreous was noted inferiorly and the anterior vitrectomy was completed.
