ABSTRACT
A 21-year-old female presented to the oculoplastic clinic with a 2-year history of raised lesions in the right upper eyelid and lateral canthus area. Due to their unusual appearance, the patient underwent an excisional biopsy of the lateral canthus lesion. A diagnosis of granuloma annulare was made after histopathology demonstrated palisading epithelioid granulomas with central fibrinoid necrosis and Alician blue positive acid mucin. Granuloma annulare is a benign inflammatory skin condition characterized by firm discolored papules or nodules classically arranged in an annular pattern. Periocular involvement is extremely rare in adults and may pose a diagnostic challenge to ophthalmologists unfamiliar with its presentation and management.
Subject(s)
Granuloma Annulare , Ophthalmologists , Female , Humans , Child , Adult , Young Adult , Granuloma Annulare/diagnosis , Granuloma Annulare/pathology , Biopsy , Mucin-1 , MucinsABSTRACT
Appendicitis is a common presentation to an acute general surgical on call team. It can be a difficult diagnosis at times, particularly in sexually active young women, in whom it is often surgically challenging. This case is of a relatively straightforward diagnosis, taken for laparoscopic appendicectomy that resulted in performing an open right hemicolectomy for a necrotic, intussuscepted appendix. Histology ultimately revealed the cause of intussusception and resultant infarction of the appendix to be endometriosis.
Subject(s)
Appendicitis/diagnosis , Appendix/pathology , Cecal Diseases/diagnosis , Colectomy , Endometriosis/diagnosis , Intussusception/diagnosis , Laparoscopy , Adult , Appendectomy , Appendicitis/etiology , Appendicitis/surgery , Cecal Diseases/complications , Cecal Diseases/pathology , Cecal Diseases/surgery , Diagnosis, Differential , Endometriosis/complications , Endometriosis/pathology , Female , Humans , Intussusception/etiology , Intussusception/surgeryABSTRACT
This case of genital ulceration and social concerns in a preschool aged child was highly suspicious for child sexual abuse. However, the lesions presumed to be herpes simplex did not respond to antiviral medication. Specialist input from paediatric oncology and endocrinology resulted in a rare diagnosis of langerhans cell histiocytosis. Furthermore, the complication of diabetes insipidus later developed, making this the youngest child described to our knowledge with vulval lesions of langerhans cell histiocytosis and a central nervous system complication.
Subject(s)
Child Abuse, Sexual/diagnosis , Histiocytosis, Langerhans-Cell/pathology , Skin Ulcer/etiology , Vulvar Diseases/pathology , Child, Preschool , Diagnosis, Differential , Female , Herpes Genitalis/diagnosis , Histiocytosis, Langerhans-Cell/complications , Histiocytosis, Langerhans-Cell/drug therapy , Humans , Vulvar Diseases/virologyABSTRACT
Sarcomatoid carcinoma is a rare tumor with a poor prognosis, otherwise known as carcinosarcoma. Gastrointestinal origin is very rare and only a limited number of anal carcinosarcomas have been reported in the literature. The management of this rare cancer type is controversial. The aim of this case report was to confirm that by combining treatment modalities we can achieve long disease free intervals. Concomitant chemoradiotherapy led to a good partial response and this was followed by a consolidation surgical endo-anal excision.
ABSTRACT
Rare cases of intracranial chondromas have been documented in the literature, often after complete surgical excision. We describe a case of giant intracranial tumor at post-mortem examination of a man who had survived 48 years after a partial debulking. Histological examination revealed a chondroid tumor with no significant pleomorphism and central cystic degeneration. Our case illustrates the benignity of the intracranial chondroma and to our knowledge, is one of the longest surviving and largest cases found after incomplete removal.