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1.
J Craniofac Surg ; 2024 Feb 16.
Article in English | MEDLINE | ID: mdl-38363317

ABSTRACT

To gain more insight into facial muscle function, imaging during action would be optimal. Magnetic resonance imaging is highly suitable for visualizing facial muscles. However, magnetic resonance imaging requires the individual to remain as still as possible for a while. Knowledge of the ability to sustain facial expressions is requisite before scanning individuals. This could help adapting the scanning protocol to obtain optimal quality of imaging the muscles in action. A study, including 10 healthy volunteers, was done to perceive the extent of movement while holding facial expressions of smiling and pouting. During 6 minutes, 3-dimensional photographs were taken every consecutive minute while the participants maintained their facial expressions as motionless as possible. The movement was objectified by creating distance maps between the 2 models and calculating the Root Mean Square using the software 3DMedX. The results showed that most movements occurred in the first minute, with a decrease of the intensity of the expression. After the first minute, the expression, although less intense, could be held stable. This implies that magnetic resonance imaging scanning during facial expression is possible, provided that the scanning starts after the first minute has elapsed. In addition, results demonstrated that more slackening of the muscles while smiling compared with pouting.

2.
Clin Exp Rheumatol ; 41(12): 2418-2427, 2023 Dec.
Article in English | MEDLINE | ID: mdl-38019170

ABSTRACT

OBJECTIVES: To prospectively investigate patient-reported outcomes and clinical performance of implant supported overdentures in edentulous Sjögren's disease (SjD) patients compared to subjects without SjD. METHODS: 51 implants were placed in 12 patients with SjD and 50 implants in 12 non-SjD patients to support overdentures. Clinical performance, marginal bone-level changes, patient satisfaction and oral health related quality of life (OHRQoL) were assessed at 1 (T1), 6 (T6), 12 (T12) and 18 (T18) months after placement of the overdenture. Patient satisfaction, ability to chew and OHRQoL were assessed with validated questionnaires. Marginal bone-level changes were measured on standardised dental radiographs. Clinical parameters included implant and overdenture survival, plaque, bleeding and gingival indices, and probing depth. RESULTS: OHRQoL in patients with SjD improved significantly after placement of implant supported overdentures at all measuring moments compared to baseline (p<0.05). Nevertheless, ability to chew tough and hard food was significantly better for non-SjD patients at all timepoints after placement of an implant supported overdenture (p<0.05). Implant survival at T18 was 100% in the patients with SjD and 98% in the non-SS group. Mean marginal bone loss at T18 did not differ between patients with SjD and non-SS patients, 1.12±0.74 mm and 1.43±1.66 mm, respectively (p=0.58). Clinical performance was good with no differences between the groups for all outcome measures (p>0.05). CONCLUSIONS: Implant-supported overdentures have a positive effect on OHRQoL and dental implants can be successfully applied in edentulous patients with SjD with nearly similar outcomes as in non-SjD subjects.


Subject(s)
Denture, Overlay , Quality of Life , Humans , Prospective Studies , Patient Satisfaction , Dental Prosthesis, Implant-Supported
3.
Brain Spine ; 3: 101767, 2023.
Article in English | MEDLINE | ID: mdl-37383454

ABSTRACT

Introduction: Evaluating patient-reported outcomes (PROMs) helps optimize preoperative counseling and psychosocial care for patients who underwent cranioplasty. Research question: This study aimed to evaluate cosmetic satisfaction, level of self-esteem, and fear of negative evaluation (FNE) of patients who underwent cranioplasty. Material and methods: Patients who underwent cranioplasty from 1 January 2014 to 31 December 2020 â€‹at University Medical Center Utrecht and a control group consisting of our center' employees were invited to fill out the Craniofacial Surgery Outcomes Questionnaire (CSO-Q), consisting of an assessment of cosmetic satisfaction, the Rosenberg Self-Esteem Scale (RSES), and the FNE scale. To test for differences in results, chi-square tests and T-tests were performed. Logistic regression was used to study the effect of cranioplasty-related variables on cosmetic satisfaction. Results: Cosmetic satisfaction was seen in 44/80 patients (55.0%) and 52/70 controls (74.3%) (p â€‹= â€‹0.247). Thirteen patients (16.3%) and 8 controls (11.4%) had high self-esteem (p â€‹= â€‹0.362), 51 patients (63.8%) and 59 controls (84.3%) had normal self-esteem (p â€‹= â€‹0.114), and 7 patients (8.8%) and 3 controls (4.3%) had low self-esteem (p â€‹= â€‹0.337). Forty-nine patients (61.3%) and 39 controls (55.7%) had low FNE (p â€‹= â€‹0.012), 8 patients (10.0%) and 18 controls (25.7%) had average FNE (p â€‹= â€‹0.095), and 6 patients (7.5%) and 13 controls (18.6%) had high FNE (p â€‹= â€‹0.215). Cosmetic satisfaction was associated with glass fiber-reinforced composite implants (OR 8.20, p-value â€‹= â€‹0.04). Discussion and conclusion: This study prospectively evaluated PROMs following cranioplasty, for which we found favorable results.

4.
World Neurosurg ; 175: e693-e703, 2023 Jul.
Article in English | MEDLINE | ID: mdl-37037366

ABSTRACT

BACKGROUND: Cranioplasty after craniectomy can result in high rates of postoperative complications. Although determinants of postoperative outcomes have been identified, a prediction model for predicting cranioplasty implant survival does not exist. Thus, we sought to develop a prediction model for cranioplasty implant survival after craniectomy. METHODS: We performed a retrospective cohort study of patients who underwent cranioplasty following craniectomy between 2014 and 2020. Missing data were imputed using multiple imputation. For model development, multivariable Cox proportional hazards regression analysis was performed. To test whether candidate determinants contributed to the model, we performed backward selection using the Akaike information criterion. We corrected for overfitting using bootstrapping techniques. The performance of the model was assessed using discrimination and calibration. RESULTS: A total of 182 patients were included (mean age, 43.0 ± 19.7 years). Independent determinants of cranioplasty implant survival included the indication for craniectomy (compared with trauma-vascular disease: hazard ratio [HR], 0.65 [95% confidence interval (CI), 0.36-1.17]; infection: HR, 0.76 [95% CI, 0.32-1.80]; tumor: HR, 1.40 [95% CI, 0.29-6.79]), cranial defect size (HR, 1.01 per cm2 [95% CI, 0.73-1.38]), use of an autologous bone flap (HR, 1.63 [95% CI, 0.82-3.24]), and skin closure using staples (HR, 1.42 [95% CI, 0.79-2.56]). The concordance index of the model was 0.60 (95% CI, 0.47-0.73). CONCLUSIONS: We have developed the first prediction model for cranioplasty implant survival after craniectomy. The findings from our study require external validation and deserve further exploration in future studies.


Subject(s)
Decompressive Craniectomy , Plastic Surgery Procedures , Humans , Young Adult , Adult , Middle Aged , Surgical Flaps/surgery , Retrospective Studies , Decompressive Craniectomy/methods , Skull/surgery , Postoperative Complications/epidemiology , Postoperative Complications/surgery
5.
Plast Reconstr Surg Glob Open ; 11(1): e4762, 2023 Jan.
Article in English | MEDLINE | ID: mdl-36776597

ABSTRACT

Facial expressions are ubiquitous in communication. Therefore, assessment of mimic function is essential in facial surgery, but no reference standards are currently available. This prospective study aims to create reference values of three-dimensional landmark displacement for different sex and age groups. Methods: Three-dimensional photographs were taken from healthy subjects in rest, maximum closed smile, and pouting. Displacement for both exercises of perioral landmarks was analyzed with MATLAB as absolute displacement and as the ratio of mouth width. Additionally, displacement in three planes was analyzed for each landmark. Averages were calculated for both genders in four age groups: 4-8, 8-12, 12-16, and >16 years. Results: In total, 328 subjects were included. Oral landmarks predominantly moved forward and backward for both exercises. Nasal landmarks predominantly moved vertically. Growing up, oral landmark displacement decreased for smiling, whereas nasal landmark displacement increased. For pouting, oral landmark displacement increased while growing up, whereas nasal landmark displacement decreased. Conclusions: The present study creates reference values for movement of perioral structures for different sex and age groups, for two facial expressions. These data are of great value for the assessment of mimic function and give insight into the development of facial animation over time.

6.
Clin Oral Implants Res ; 34(3): 177-195, 2023 Mar.
Article in English | MEDLINE | ID: mdl-36645164

ABSTRACT

OBJECTIVES: The aim of this study was the preclinical and clinical evaluation of osteoinductive calcium phosphate with submicron surface topography as a bone graft substitute for maxillary sinus floor augmentation (MSFA). MATERIAL AND METHODS: A preclinical sheep model of MSFA was used to compare a calcium phosphate with submicron needle-shaped topography (BCPN , MagnetOs Granules, Kuros Biosciences BV) to a calcium phosphate with submicron grain-shaped topography (BCPG ) and autologous bone graft (ABG) as controls. Secondly, a 10-patient, prospective, randomized, controlled trial was performed to compare BCPN to ABG in MSFA with two-stage implant placement. RESULTS: The pre-clinical study demonstrated that both BCPN and BCPG were highly biocompatible, supported bony ingrowth with direct bone apposition against the material, and exhibited bone formation as early as 3 weeks post-implantation. However, BCPN demonstrated significantly more bone formation than BCPG at the study endpoint of 12 weeks. Only BCPN reached an equivalent amount of bone formation in the available space and a greater proportion of calcified material (bone + graft material) in the maxillary sinus compared to the "gold standard" ABG after 12 weeks. These results were validated in a small prospective clinical study, in which BCPN was found comparable to ABG in implant stability, bone height, new bone formation in trephine core biopsies, and overall clinical outcome. CONCLUSION: This translational work demonstrates that osteoinductive calcium phosphates are promising bone graft substitutes for MSFA, whereas their bone-forming potential depends on the design of their surface features. Netherlands Trial Register, NL6436.


Subject(s)
Bone Substitutes , Sinus Floor Augmentation , Animals , Bone Transplantation/methods , Calcium Phosphates , Dental Implantation, Endosseous , Maxillary Sinus/surgery , Prospective Studies , Sheep , Sinus Floor Augmentation/methods , Humans
7.
J Clin Med ; 11(24)2022 Dec 07.
Article in English | MEDLINE | ID: mdl-36555875

ABSTRACT

Smile appearance has a major psychological impact. Orthognathic surgery, which has harmonizing results on skeletal structures, can negatively influence the smile appearance due to soft tissue effects. To enhance the aesthetic effects of orthognathic surgery on soft tissues, reference models for large parts of the hospital's adherent area are called for. This study aims to create average facial models for different sex and age groups in two facial exercises: maximum closed smile, and pouting. These models were created using coherent point drift and Procrustes algorithms in MATLAB. Principal component analysis was performed, and of 20 surgical landmarks, the in-group variation using standard deviation was calculated. Three distances were analyzed: nasal width, philtral width, and mouth width. To correct for facial size, these distances were analyzed as a ratio of intercanthal width. In total, 328 healthy subjects were included in the study. Subjects were grouped by sex, and in age categories spanning four years each, with an adult group with all ages >16 years. For both smiling and pouting faces, all ratios increased with ageing. These templates and data can benefit facial surgeons, to obtain an expected outcome according to the age of the patient.

8.
Clin Oral Implants Res ; 33(11): 1157-1170, 2022 Nov.
Article in English | MEDLINE | ID: mdl-36136091

ABSTRACT

OBJECTIVES: To prospectively assess the clinical performance and patient-reported outcomes of dental implants in dentate patients with primary and secondary Sjögren's syndrome (pSS and sSS, respectively) compared to patients without SS. MATERIALS AND METHODS: Thirty-seven implants were placed in 17 patients with pSS/sSS and 26 implants in 17 non-SS patients to replace missing (pre)molars. Clinical performance, marginal bone-level changes, patient satisfaction, and oral health-related quality of life (OHRQoL) were assessed at 1 (T1), 6 (T6), 12 (T12), and 18 (T18) months after placement of the superstructure. Marginal bone-level changes were measured on standardized dental radiographs. Clinical parameters included implant and crown survival, plaque, bleeding and gingival indices, and probing depth. Patient satisfaction and OHRQoL were assessed with validated questionnaires. RESULTS: Implant survival at T18 was 100% in the patients with pSS/sSS and 96.2% in the non-SS group. Mean marginal bone loss at T18 did not differ between patients with pSS/sSS and non-SS patients, 1.10 ± 1.04 and 1.04 ± 0.75 mm, respectively (p = .87). Clinical performance was good with no differences between the groups for all outcome measures (p > .05). OHRQoL in patients with pSS/sSS had improved significantly after placement of implant supported crowns at all measuring moments compared to baseline (p < .05). Nevertheless, patient satisfaction and OHRQoL remained significantly higher for patients without SS at all measuring moments (p < .05). CONCLUSION: Dental implants can be successfully applied in dentate patients with pSS/sSS and have a positive effect on OHRQoL.


Subject(s)
Dental Implants , Sjogren's Syndrome , Humans , Sjogren's Syndrome/complications , Prospective Studies , Quality of Life , Crowns , Dental Prosthesis, Implant-Supported
9.
Plast Reconstr Surg Glob Open ; 10(2): e4113, 2022 Feb.
Article in English | MEDLINE | ID: mdl-35186646

ABSTRACT

Decreased smile dynamics is reported as an unwanted side effect after Le Fort I osteotomies. It is assumed that this negative sequela might be caused by postoperative changes in the anatomy of peri-oral mimic muscles. Due to a lack of specific anatomical knowledge, the exact mechanism is not yet clarified. This makes prevention of the undesired changes in smile dynamics difficult. The first aim of this study is to increase basic anatomical and radiological MRI knowledge of the peri-oral mimic muscles. The second aim is to investigate if 7 Tesla MRI scans are better suited to identify these muscles than 3 Tesla MRI scans. METHODS: Eleven peri-oral mimic muscles were chosen as subjects of the present study. Three and 7 Tesla MRI scans of a cadaver head were made. The same head was cut in axial slices using a cryomacrotome. Every second slice was digitally photographed. A three-dimensional model was created utilizing EMAC software, which served as gold standard for the identification and comparison of the chosen peri-oral mimic muscles on both MRI scans. RESULTS: All predetermined peri-oral mimic muscles could be identified in the cadaver head, and a detailed radiological atlas was created. The ease of identification and separation of the peri-oral mimic muscles was significantly higher on the 7 Tesla MRI than on the 3 Tesla MRI scan (P < 0.001). CONCLUSION: A 7 Tesla MRI scanner offers great improvement in the identification of peri-oral mimic muscles compared with a 3 Tesla scanner.

10.
Plast Reconstr Surg ; 143(5): 1456-1465, 2019 05.
Article in English | MEDLINE | ID: mdl-30789482

ABSTRACT

BACKGROUND: Numerous studies have proven the efficacy of mandibular distraction osteogenesis or tongue-lip adhesion in Robin sequence infants with upper airway obstruction. However, none has compared health-related quality of life outcomes. METHODS: In the present retrospective study, Robin sequence infants younger than 1 year, who underwent mandibular distraction osteogenesis or tongue-lip adhesion, were included (2006 to 2016). The infants' caregivers were asked to complete a questionnaire based on the Glasgow Children's Benefit Inventory. RESULTS: The response rate was 71 percent (22 of the 31 questionnaires; mandibular distraction osteogenesis, 12 of 15; and tongue-lip adhesion, 10 of 16) and median age at surgery was 24 days (range, 5 to 131 days). Median total Glasgow Children's Benefit Inventory scores after mandibular distraction osteogenesis and after tongue-lip adhesion were 21.9 (interquartile range, 9.4) and 26.0 (interquartile range, 37.5), respectively (p = 0.716), indicating an overall benefit from both procedures. Positive changes were observed in all subgroups emotion, physical health, learning, and vitality. In syndromic Robin sequence, both procedures demonstrated a lower positive change in health-related quality of life compared with isolated Robin sequence (p = 0.303). CONCLUSIONS: Both surgical procedures demonstrated an overall benefit in health-related quality-of-life outcomes, with no significant differences. The authors' findings contribute to the debate regarding the use of mandibular distraction osteogenesis versus tongue-lip adhesion in the surgical treatment of Robin sequence; however, studies evaluating health-related quality of life in larger Robin sequence cohorts are necessary to identify which procedure is likely to be best in each individual Robin sequence infant. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, III.


Subject(s)
Lip/surgery , Mandible/surgery , Osteogenesis, Distraction/methods , Pierre Robin Syndrome/surgery , Quality of Life , Tongue/surgery , Caregivers/statistics & numerical data , Female , Humans , Infant , Infant, Newborn , Male , Mandible/abnormalities , Retrospective Studies , Surveys and Questionnaires/statistics & numerical data , Tissue Adhesions/etiology , Tongue/abnormalities , Treatment Outcome
11.
Int J Pediatr Otorhinolaryngol ; 106: 10-15, 2018 Mar.
Article in English | MEDLINE | ID: mdl-29447879

ABSTRACT

OBJECTIVES: The aim of our study was to investigate subjective information concerning parental experiences and preferences with regard to the initial information that is provided right after the birth of a child with microtia. The analysis of these data is intended to help professionals improve the way in which such conversations are conducted. As a result, future parents may feel better informed and, hence, better fit to cope with challenges they may encounter having a child with microtia. METHODS: A self-administered questionnaire was sent to 106 parents and caretakers of children with microtia who visited the annual International Microtia and Atresia Conference in the Netherlands, May 2016. RESULTS: Eighty-seven questionnaires were returned (response rate 82%). Results revealed that 26% of the participants did not receive any information about the condition in the perinatal period. Participants who did receive information right after birth were informed by pediatricians and otolaryngolosits in most of the cases. Plastic surgeons and maxillofacial surgeons were the less commonly serving specialties in this role. A majority of the participants experienced their informing consultation as either being "terrible", or "bad". Parents desired more information about all domains regarding microtia. Development, clothing and appearance, and psychology were believed to be the least important domains. CONCLUSIONS: Parents are dissatisfied with several aspects of the initial information that is provided right after the birth of a child with microtia. We believe that there is a need for correct information and patient- and family centered care administered by multiple disciplines.


Subject(s)
Congenital Microtia/therapy , Health Education/methods , Parents/education , Physician-Patient Relations , Child , Female , Humans , Male , Netherlands , Parents/psychology , Referral and Consultation , Surveys and Questionnaires
13.
Clin Oral Investig ; 19(8): 2101-14, 2015 Nov.
Article in English | MEDLINE | ID: mdl-25680705

ABSTRACT

OBJECTIVES: Initial approaches to and treatments of infants with Robin sequence (RS) is diverse and inconsistent. The care of these sometimes critically ill infants involves many different medical specialties, which can make the decision process complex and difficult. To optimize the care of infants with RS, we present our institution's approach and a review of the current literature. MATERIAL AND METHODS: A retrospective cohort study was conducted among 75 infants diagnosed with RS and managed at our institution in the 1996-2012 period. Additionally, the conducted treatment regimen in this paper was discussed with recent literature describing the approach of infants with RS. RESULTS: Forty-four infants (59%) were found to have been treated conservatively. A significant larger proportion of nonisolated RS infants than isolated RS infants needed surgical intervention (53 vs. 25%, p = .014). A mandibular distraction was conducted in 24% (n = 18) of cases, a tracheotomy in 9% (n = 7), and a tongue-lip adhesion in 8% (n = 6). Seventy-seven percent of all infants had received temporary nasogastric tube feeding. The literature review of 31 studies showed that initial examinations and the indications to perform a surgical intervention varied and were often not clearly described. CONCLUSIONS: RS is a heterogenic group with a wide spectrum of associated anomalies. As a result, the decisional process is challenging, and a multidisciplinary approach to treatment is desirable. Current treatment options in literature vary, and a more uniform approach is recommended. CLINICAL RELEVANCE: We provide a comprehensive and pragmatic approach to the analysis and treatment of infants with RS, which could serve as useful guidance in other clinics.


Subject(s)
Pierre Robin Syndrome/physiopathology , Pierre Robin Syndrome/surgery , Follow-Up Studies , Humans , Infant , Male , Retrospective Studies
14.
J Craniomaxillofac Surg ; 42(8): 1918-23, 2014 Dec.
Article in English | MEDLINE | ID: mdl-25213198

ABSTRACT

INTRODUCTION: Intraoperative imaging seems to be the next step to improve surgical outcome in the treatment of zygomaticomaxillary complex (ZMC) fractures. Many publications have appeared on intraoperative imaging for trauma surgery, but in most hospitals intraoperative imaging is not routinely performed for ZMC fracture repair. The goal of this review was to assess the value of intraoperative imaging in ZMC fracture repair. MATERIAL AND METHODS: The literature was reviewed with focus on the effects of intraoperative imaging on facial symmetry, fracture reduction and the frequency of additional reduction after intraoperative imaging in ZMC fractures. RESULTS: Six publications were found on the frequency of additional reduction after intraoperative imaging in ZMC fracture repair. Revision of the reduction of the zygoma was performed in 18% (95% CI 10.5%-29.0%), revision of the orbital floor was performed in 9% (95% CI 3.6%-17.2%). No publications were found on the effects of intraoperative imaging on facial symmetry or on the accuracy of fracture reduction. CONCLUSIONS: Information obtained from intraoperative imaging often has consequences on the surgical management of ZMC fractures. However, the effect on restoration of facial symmetry and fracture reduction is yet to be established.


Subject(s)
Diagnostic Imaging/methods , Intraoperative Care , Maxillary Fractures/diagnosis , Zygomatic Fractures/diagnosis , Fracture Fixation/methods , Humans , Maxillary Fractures/surgery , Radiography, Interventional/methods , Ultrasonography, Interventional/methods , Zygomatic Fractures/surgery
15.
Br J Oral Maxillofac Surg ; 52(3): 223-9, 2014 Mar.
Article in English | MEDLINE | ID: mdl-24388657

ABSTRACT

Many treatments have been described for infants with Robin sequence and severe respiratory distress, but there have not been many comparative studies of outcome and cost-effectiveness. The aim of this study was to compare the cost and complications of two common interventions - mandibular distraction osteogenesis and tracheostomy. Nine patients with isolated Robin sequence (mandibular distraction osteogenesis, n=5, and tracheostomy, n=4) were included in the analyses. Predetermined costs and complications were obtained retrospectively from medical records and by questionnaires to the parents over a 12-month period. Overall direct costs (admission to hospital, diagnostics, surgery, and homecare) were 3 times higher for tracheostomy (€105.523 compared with €33.482, p=0.02). Overall indirect costs (absence from work) were almost 5 times higher (€2.543 compared with €543, p=0.02). There was a threefold increase in overall total cost/patient (both direct and indirect) for tracheostomy (€108.057 compared with 34.016, p=0.02) and 4 times more complications were encountered. This study shows that mandibular distraction osteogenesis in infants diagnosed with Robin sequence costs significantly less and results in fewer complications than tracheostomy, and this contributes to our current knowledge about the ideal approach for infants with Robin sequence and might provide a basis for institutional protocols in the future.


Subject(s)
Mandible/surgery , Osteogenesis, Distraction/economics , Pierre Robin Syndrome/surgery , Tracheostomy/economics , Absenteeism , Aftercare/economics , Ambulatory Care/economics , Clinical Laboratory Techniques/economics , Cost-Benefit Analysis , Critical Care/economics , Direct Service Costs/statistics & numerical data , Follow-Up Studies , Humans , Infant , Infant Care/economics , Infant, Newborn , Medical Staff, Hospital/economics , Patient Admission/economics , Pierre Robin Syndrome/economics , Postoperative Care/economics , Postoperative Complications/economics , Retrospective Studies , Treatment Outcome
16.
Clin Oral Investig ; 17(8): 1807-20, 2013 Nov.
Article in English | MEDLINE | ID: mdl-23722462

ABSTRACT

OBJECTIVES: Mandibular distraction osteogenesis (MDO) has been successfully applied in infants suffering Robin sequence (RS) with severe upper airway obstruction, but no comparative studies for the different types of MDO exist to date. The objective of the current study was to systematically review the published data considering this matter, providing a fundament for protocols and a more conscious treatment strategy for infants with RS in the near future. MATERIAL AND METHODS: For the period from January 1966 to January 2012, the Pubmed, EMBASE, and Cochrane Library databases were searched. Abstracts were screened based on predetermined selection criteria. Relevant full-text articles were retrieved. The articles were analyzed on the type of MDO used, preoperative workup, patient characteristics, postoperative outcome, and complications. RESULTS: The search yielded 109 articles. After checking abstracts and full texts on predetermined inclusion and exclusion criteria, 12 studies (four describing external MDO, five internal MDO, and three both types) were extracted for further analyses. CONCLUSION: Internal MDO seems very feasible in infants suffering RS, minimizing side effects such as hypertrophic scarring, nerve damage, and extensive care needs, although the indications for usage are more limited compared to the external device. Corresponding protocols and long-term outcome studies are needed to make a better comparison and the use and indication of the different types of distraction even more distinct. CLINICAL RELEVANCE: A base for a guideline to support the choice of a designated operative management for neonates with RS is provided, hereby obviating possible complications of the different types of MDO in the future.


Subject(s)
Mandible/surgery , Osteogenesis, Distraction/methods , Pierre Robin Syndrome/surgery , Humans , Infant , Infant, Newborn
17.
Int J Oral Maxillofac Implants ; 28(1): 222-7, 2013.
Article in English | MEDLINE | ID: mdl-23377069

ABSTRACT

PURPOSE: To compare the donor site complication rate and length of hospital stay following the harvest of bone from the iliac crest, calvarium, or mandibular ramus. MATERIALS AND METHODS: Ninety-nine consecutively treated patients were included in this retrospective observational single-center study. RESULTS: Iliac crest bone was harvested in 55 patients, calvarial bone in 26 patients, and mandibular ramus bone in 18 patients. Harvesting of mandibular ramus bone was associated with the lowest percentages of major complications (5.6%), minor complications (22.2%), and total complications (27.8%). Harvesting of iliac crest bone was related to the highest percentages of minor complications (56.4%) and total complications (63.6%), whereas harvesting of calvarial bone induced the highest percentage of major complications (19.2%). The length of the hospital stay was significantly influenced by the choice of donor site (P = .003) and age (P = .009); young patients with the mandibular ramus as the donor site had the shortest hospital stay. CONCLUSIONS: Harvesting of mandibular ramus bone was associated with the lowest percentage of complications and the shortest hospital stay. When the amount of bone to be obtained is deemed sufficient, mandibular ramus bone should be the first choice for the reconstruction of maxillofacial defects.


Subject(s)
Ilium , Length of Stay/statistics & numerical data , Mandible , Skull , Tissue and Organ Harvesting/adverse effects , Transplant Donor Site , Adolescent , Adult , Aged , Aged, 80 and over , Bone Transplantation/adverse effects , Female , Humans , Male , Mandible/surgery , Mandible/transplantation , Middle Aged , Postoperative Complications/epidemiology , Postoperative Complications/etiology , Plastic Surgery Procedures/adverse effects , Retrospective Studies , Treatment Outcome , Young Adult
18.
J Oral Maxillofac Surg ; 69(3): 870-6, 2011 Mar.
Article in English | MEDLINE | ID: mdl-20727648

ABSTRACT

PURPOSE: The purpose of this study was to determine whether a modified alar cinch suture and V-Y closure (mACVY) have a beneficial effect on labial form after Le Fort I intrusion and advancement osteotomies and whether they result in excessive upward nasal tip rotation. Both are possible effects compared with simple closing sutures (SCS). PATIENTS AND METHODS: A prospective study was carried out on 56 patients, 31 with mACVY and 25 with SCS. Lateral cephalograms taken immediately before and 18 months after operation were used, measuring horizontal and vertical changes of the following landmarks: anterior and posterior nasal spine, A-point, incision superior, pronasale, subnasale, labiale superior, and stomion superior, as well as angular changes of sella-nasion-pronasale, and changes in upper vermilion exposure. Statistical analysis was performed on intragroup, paired t test, and intergroup differences, unpaired t test (P < .05). RESULTS: The horizontal and vertical changes of labiale superior were significantly larger for mACVY versus SCS, and the angle sella-nasion-pronasale increased in mACVY versus SCS. However, no significant difference was found for vertical changes of the nasal tip. Upper vermilion exposure increased with mACVY versus SCS. CONCLUSION: mACVY has a beneficial effect on labial form, and excessive upward rotation of the nasal tip is prevented.


Subject(s)
Lip/anatomy & histology , Maxilla/abnormalities , Nasal Cartilages/anatomy & histology , Open Bite/surgery , Osteotomy, Le Fort/methods , Suture Techniques , Adolescent , Adult , Cephalometry , Female , Humans , Linear Models , Male , Mandible/surgery , Maxilla/surgery , Middle Aged , Nose Deformities, Acquired/prevention & control , Prospective Studies , Treatment Outcome , Young Adult
19.
Article in English | MEDLINE | ID: mdl-11934053

ABSTRACT

The Le Fort I osteotomy results in predictable long-term effects. The soft tissues, however, can be difficult to control because of considerable variation in their adaptation. Several adverse reactions can take place, including thinning and lateral retraction of the lip, accentuation of the nasolabial groove, reduced vermilion exposure, and increase of the nasolabial angle. In this study on 51 selected patients, the V-shaped wound in the vestibule of the maxilla after the Le Fort I osteotomy was closed with a "Y," with the bast of the "Y" in the midline of the upper lip (V-Y closure). Forward multiple regression analysis was calculated for each bony landmark. Regression equations were formulated if P < .05. The equation with the bony point with the highest r2 value was considered the most important independent variable. The selected independent variables were used to form 4 subgroups with identical vectors of movements: impaction, advancement, impaction and advancement, and dorsal impaction. In these 4 subgroups, forward multiple regression analysis was used to select equations with the highest r2 value (P < .05). The selected equations demonstrated that a V-Y plasty as single soft tissue procedure suffices only in advancement cases, and only if the nose does not need additional upward rotation. In the other 3 subgroups, additional procedures are necessary, such as alar cinch suture, reduction of the anterior nasal spine, or grinding of the paranasal area in order to prevent the above-mentioned adverse soft tissue changes.


Subject(s)
Esthetics, Dental , Lip/pathology , Nose/pathology , Osteotomy, Le Fort/statistics & numerical data , Surgical Flaps/statistics & numerical data , Adolescent , Adult , Bone Plates , Bone Wires , Cephalometry , Female , Humans , Lip Diseases/etiology , Male , Maxilla/pathology , Maxilla/surgery , Maxillary Sinus/surgery , Movement , Nasal Bone/surgery , Nose/surgery , Nose Diseases/etiology , Osteotomy, Le Fort/adverse effects , Osteotomy, Le Fort/methods , Regression Analysis , Rotation , Sphenoid Bone/surgery , Surgical Flaps/adverse effects , Suture Techniques
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