Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 3 de 3
Filter
Add more filters










Database
Language
Publication year range
2.
Clin J Gastroenterol ; 14(5): 1337-1343, 2021 Oct.
Article in English | MEDLINE | ID: mdl-34296396

ABSTRACT

A man in his 60s underwent esophagogastroduodenoscopy (EGD) for gastric cancer screening in 2006. A pale, oval, depressed lesion, 8 mm in diameter, was seen in the greater curvature of the gastric antrum. The patient was followed up every 1-2 years. EGD performed 13 years after 2006 showed the lesion with an irregular margin. Histopathological diagnosis of a target biopsy was signet-ring cell carcinoma. The lesion was resected by endoscopic submucosal dissection. The resected specimen was 8 × 3 mm in size, and histopathological examination showed type 0-IIc, signet-ring cell carcinoma, pT1a, Ly0, V0, UL0, pHM0, pVM0. The patient had no history of Helicobacter pylori infection. The serum anti-H. pylori IgG antibody test result and the urea breath test result was negative. Histopathological examination did not reveal the presence of H. pylori. No evidence of atrophic gastritis on endoscopy was found. Based on these findings, the patient was confirmed as not having H. pylori infection. We retrospectively reviewed all previous endoscopic images and confirmed that the lesion was already present in the images taken 17 years ago. To our knowledge, this is the longest retrospective follow-up (17 years) of gastric signet-ring cell carcinoma remaining in the mucosa, without H. pylori infection.


Subject(s)
Carcinoma, Signet Ring Cell , Stomach Neoplasms , Carcinoma, Signet Ring Cell/diagnosis , Carcinoma, Signet Ring Cell/surgery , Follow-Up Studies , Gastric Mucosa , Humans , Male , Retrospective Studies , Stomach Neoplasms/diagnosis , Stomach Neoplasms/surgery
3.
Intern Med ; 56(15): 1967-1971, 2017.
Article in English | MEDLINE | ID: mdl-28768965

ABSTRACT

A 68-year-old man with occult hepatitis B virus (HBV) infection was diagnosed with malignant lymphoma and achieved complete remission after treatment with a chemotherapy regimen including rituximab for 5 months. Entecavir (ETV) was also used during and after chemotherapy and was ended at 14 months after chemotherapy. However, reactivation of HBV was observed in blood tests, which showed not only elevation of HBV-DNA but also HBsAg and HBeAg, at 27 months after the end of chemotherapy. After restarting ETV, the HBV-DNA levels immediately subsided. In addition, anti-HBs became and remained positive at 31 months after chemotherapy. ETV was re-discontinued at 36 months after chemotherapy.


Subject(s)
Antiviral Agents/therapeutic use , Guanine/analogs & derivatives , Hepatitis B virus/physiology , Hepatitis B/drug therapy , Lymphoma/drug therapy , Rituximab/therapeutic use , Aged , Antibodies, Monoclonal, Murine-Derived/therapeutic use , Antiviral Agents/administration & dosage , Guanine/administration & dosage , Guanine/therapeutic use , Hepatitis B/physiopathology , Hepatitis B Antibodies , Hepatitis B Surface Antigens/blood , Hepatitis B e Antigens , Humans , Male , Rituximab/administration & dosage , Virus Activation
SELECTION OF CITATIONS
SEARCH DETAIL
...