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Klin Lab Diagn ; 61(4): 223-5, 2016 Apr.
Article in Russian | MEDLINE | ID: mdl-30586241

ABSTRACT

According publications' data, hairy cell leukosis encounters in humans aged from 26 to 70 years and in males four times more often than in females. The disease is manifested by impotence, splenomegaly, and presence in blood and bone marrow clone of lymphoid cells with particular morphology, cytochemic markers and immune phenotype (sIg+, CD19+, CD20+, CD5-, CD10-, with marked expression of CD25+, CD103+). The presented clinical case of illness with hairy cell leucosis is the first one detected in pediatric practice in adolescent of 16 years old.


Subject(s)
Acid Phosphatase/blood , Flow Cytometry , Leukemia, Hairy Cell/blood , Leukemia, Hairy Cell/pathology , Adolescent , Antigens, CD/blood , Antigens, CD19/blood , Antigens, CD20/blood , B-Lymphocytes/pathology , Female , Humans , Integrin alpha Chains/blood , Interleukin-2 Receptor alpha Subunit/blood , Isoenzymes/blood , Lymphocytes/pathology
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