Anastomosis Groups of Rhizoctonia solani and Binucleate Rhizoctonia Associated with Potatoes in Idaho.

A survey of the relative incidence of anastomosis groups (AGs) of Rhizoctonia spp. associated with potato disease was conducted in Idaho, the leading potato producing state in the U.S.A. In total, 169 isolates of Rhizoctonia solani and seven binucleate Rhizoctonia (BNR) isolates were recovered from diseased potato plants. The AG of each isolate was determined through real-time PCR assays for AG 3-PT and phylogenetic analysis of the internal transcribed spacer region of ribosomal DNA. AG 3-PT was the predominant AG, accounting for 85% of isolates recovered, followed by AG 2-1 (5.7%) and AG 4 HG-II (4.5%). Two different subsets of AG 2-1 isolates were recovered (subset 2 and 3). Three isolates each of AG A and AG K were recovered, as well as one isolate each of AG 5 and AG W. An experiment carried out under greenhouse conditions with representative isolates of the different AGs recovered from Idaho potatoes showed differences in aggressiveness between AGs to potato stems, with AG 3-PT being the most aggressive followed by an isolate of AG 2-1 (subset 3). The three BNR isolates representative of AG A, AG K, and AG W appeared to be less aggressive to potato stems than the R. solani isolates except for the AG 2-1 (subset 2) isolate. This is the first comprehensive study of the relative incidences of Rhizoctonia species associated with Idaho potatoes and the first study to report the presence of BNR AG W outside of China.

Sustained rescue of prefrontal circuit dysfunction by antidepressant-induced spine formation.

The neurobiological mechanisms underlying the induction and remission of depressive episodes over time are not well understood. Through repeated longitudinal imaging of medial prefrontal microcircuits in the living brain, we found that prefrontal spinogenesis plays a critical role in sustaining specific antidepressant behavioral effects and maintaining long-term behavioral remission. Depression-related behavior was associated with targeted, branch-specific elimination of postsynaptic dendritic spines on prefrontal projection neurons. Antidepressant-dose ketamine reversed these effects by selectively rescuing eliminated spines and restoring coordinated activity in multicellular ensembles that predict motivated escape behavior. Prefrontal spinogenesis was required for the long-term maintenance of antidepressant effects on motivated escape behavior but not for their initial induction.

Establishment of primary stroke centers: a survey of physician attitudes and hospital resources.

OBJECTIVES: To survey US physicians involved in acute stroke care to determine the proportion of hospitals that currently meet the recommended Brain Attack Coalition (BAC) criteria for Primary Stroke Centers (PSC) and obtain opinions regarding the value of stroke centers. METHODS: A survey regarding the BAC guidelines for the establishment of stroke centers was mailed to 3,245 US neurologists, neurosurgeons, and emergency physicians. RESULTS: A total of 1,032 responses were received. Seventy-nine percent (range by specialty 58 to 98%) of respondents believed there was a need for stroke centers. If formal stroke center designation were established, 81% (range 72 to 90%) would like their hospital to become a PSC. Although 77% of respondents believed that their hospital currently met recommended criteria for a PSC, only 7% actually meet all recommended elements. However, 44% of hospitals already provide most acute stroke services. The BAC criteria most frequently lacking were continuing medical education for professional stroke center staff, stroke training for emergency department staff, formal establishment of a stroke unit, and designation of a stroke center director. CONCLUSIONS: The majority of emergency medicine and neuroscience physician respondents involved in acute stroke care support the designation of primary stroke centers. Although respondents globally overestimated the extent to which their facilities currently meet BAC recommended criteria for PSC, detailed responses suggested that over 40% of hospitals possess substantial existing acute stroke care resources and are poised to function as PSC with modest additional administrative and financial commitment.

The psychopathy checklist--screening version: an examination of criteria and subcriteria in three forensic samples.

The development and refinement of psychopathy represent a critical issue in clinical and forensic practice. During the last decade, important advances in the operationalization of psychopathy were achieved, primarily through the development of the Psychopathy Checklist (PCL) and its subsequent versions (PCL-R and PCL:SV). PCL ratings are based primarily on item descriptions or subcriteria. The current study serves to break new ground as the first systematic investigation of PCL:SV subcriteria by addressing their psychometric properties and exploring their construct and criterion-related validation. Previously unanalyzed data from three samples were integrated: female offenders, male forensic patients, and male adolescent offenders. Results largely support the use of subcriteria as homogeneous components of criteria and provide strong initial evidence of their construct validity. Results are less conclusive regarding criterion-related validity. For female offenders, they suggested the potential value of specific PCL:SV subcriteria for predicting verbal aggression. Confirmatory factor analysis provided encouraging results on the applicability of the standard two-factor model of psychopathy. However, a first-order principal axis factoring suggested further refinements in our understanding of psychopathy.

The contribution of small life events to the psychological distress of married and widowed older women.

The contribution of small life events to the prediction of general psychological distress was examined for 50 married and 21 recently widowed older women. These two groups were contrasted as having or not having experienced an uncontrollable major life stressor (i.e., the recent death of a spouse). Negative small life events (i.e., daily hassles) contributed above and beyond general demographic factors; conjugal bereavement status; social support; other, non-conjugal bereavement, major life events; and the interaction of these life events and social support in the prediction of general psychological distress. Results support assessing negative small life events as well as major life events for both married and recently widowed older women.

Locus of control perceptions among conjugally bereaved older adults: a pilot study.

While Locus of Control is typically operationalized as a single dispositional trait that generalizes across settings, it has also been conceptualized as two weakly related factors; Domain-Specific State Locus of Control and a generalized Trait Locus of Control. Malleability of these two factors was tested for recently widowed older adults in self-help support groups (n = 17) and a waiting-list control condition (n = 6). Domain-Specific State Locus of Control-Desire for Control subscale increased over the course of the three-week six-session intervention for support group participants. These group participants also showed decreased psychological distress from pre to post intervention. The change in Domain-Specific State Locus of Control-Desire for Control did not relate to this reduction in distress. As expected, Trait Locus of Control remained stable with greater Trait Internality related to less psychological symptomatology.

Injury prevention: a nursing responsibility.

Injury represents a major health care problem in the United States today. The rise in the number of violent crimes as well as unintentional injuries has touched Americans of all ages and in all socieconomic groups. Advances in prehospital care, acute care, and rehabilitation provided to trauma victims have helped to decrease the toll that trauma takes, but the most effective intervention is to prevent these deaths and injuries from ever occurring. Nurses are in key positions to educate the public on prevention practices, identify injury trends, influence the passage of prevention legislation, and help decrease the number of traumatic deaths and injuries occurring in our society.

Change and quality.

In the culture of most healthcare organizations, change is described by anecdotes or represented by new structures such as buildings. Change in the systems and processes that enable work in healthcare organizations often goes unmeasured and underreported.

Creating, improving, and innovating.

Technological innovations have fundamentally changed the science and practice of medicine. Increased awareness of the need to enhance processes and systems supporting delivery of safe, accessible, affordable health care has sparked an interest in creativity and innovation as essential skills in quality management. This article considers four points regarding the role of creativity and innovation in health care quality management: Creativity and innovation are essential skills in improving and enhancing health care processes and health care delivery systems; creativity is a personal characteristic that can be enhanced; innovation, the legacy of creativity, begins with values-centered design; and innovations emerge in many sizes and forms.

Reported use of autotransfusion systems in initial resuscitation areas by one hundred thirty-six United States hospitals.

INTRODUCTION: The purpose of this study was to determine autotransfusion system availability and use in the initial resuscitation area. METHODS: A 22-item questionnaire was mailed to 290 facilities across the country; 136 (46.8%) were returned. Questions included availability and use of the autotransfusion system, patient population, resistance to the system, frequency of in-service programs, use of anticoagulants, and recommendations regarding the use of autotransfusion systems. RESULTS: One hundred seven hospitals (79%) reported autotransfusion system availability. Frequency of autotransfusion system initiation was as follows: always, 17 (15.9%); most of the time, 34 (31.8%); occasionally, 41 (38.3%); and never, 15 (14%). Not all patients who had an autotransfusion system initiated received shed blood. The most frequent reasons for not using an autotransfusion system were as follows: "not requested by medical staff," n = 50; "no need for autotransfusion system," n = 33; "preferred banked blood," n = 25; and "did not use [often] enough to maintain skill," n = 21. Those with more than one in-service program per year were more likely to use an autotransfusion system than those with one in-service program per year. DISCUSSION: The majority of hospitals surveyed had autotransfusion system availability; however, autotransfusion system use was inconsistent. Two major areas influencing autotransfusion system use were having specific criteria for use and educational factors.

Tridimensional Personality Questionnaire and serotonin in bulimia nervosa.

To determine the relationship between Tridimensional Personality Questionnaire (TPQ) scales and bulimia nervosa, TPQ scores of 27 bulimic women, age range 21-59, were compared with values for an age-matched sample of 128 normal control women drawn from the national norming sample by Przybeck. Scores for Novelty Seeking and Harm Avoidance were significantly higher, while scores for Reward Dependence were significantly lower for the bulimic women. A stepwise regression model of severity of purging on TPQ selected Novelty Seeking and a composite depression score, with Novelty Seeking being the stronger of the two predictors. Whole blood serotonin levels did not relate to TPQ scores or to purging frequency.

The continuous improvement-focused quality improvement plan.

The QI plan of a department or functional area is a statement of philosophy about quality improvement and a guide to doing quality improvement. In that sense, the QI plan is both a roadmap and a description of the journey. The form of the QI plan varies by organization and is a reflection of the individual style of the organization. The substance of the plan is important. QI plan developers who consider structure, process and outcome will generate a viable document that supports meaningful quality improvement.