ABSTRACT
BACKGROUND: Glomus tumours are neoplasms arising from cells of the neuromyoarterial glomus bodies, which almost always occur in a subungual location. A lung location is extremely rare, with few cases reported in the literature. CLINICAL CASE: The case is presented of a 33 year-old male, with non-productive cough, dyspnoea at rest, intermittent fever, and mild pain in rib cage. A chest radiograph showed a consolidation in the left lung, and computed tomography revealed a lesion in the hilum that extended to the bronchus of the lingula obstructing, and causing post-obstructive pneumonia. A biopsy was obtained by rigid bronchoscopy biopsy, which showed a well circumscribed tumour constituted by intermediate-sized cells, and abundant cytoplasm that are arranged in a pattern surrounding numerous thin-walled blood vessels, with no pleomorphism, significant mitotic activity or necrosis. Immunohistochemistry revealed diffuse positivity with smooth muscle actin, vimentin, caldesmon; focal reactivity with desmin and CD117, CD34 highlights the vascular pattern. Ki67 proliferation rate was 1%. Synaptophysin, EMA and cytokeratin cocktail were negative, making the diagnosis of glomus tumour. CONCLUSIONS: Glomus tumours are rare neoplasms that usually appear in the dermis and subcutaneous tissue, where it is common to find glomus bodies. Occasionally glomus tumours can occur in extra-cutaneous sites such as the gastrointestinal tract, bone and respiratory system, with this case being a new case of rare lung location.
Subject(s)
Glomus Tumor , Lung Neoplasms , Adult , Glomus Tumor/diagnosis , Glomus Tumor/surgery , Humans , Lung Neoplasms/diagnosis , Lung Neoplasms/surgery , MaleABSTRACT
La esplenosis torácica se define como la presencia de implantes de tejido esplénico en la pleura parietal o visceral, secundaria a una rotura del bazo o traumatismo esplénico o diafragmático. Es una entidad rara, con síntomas poco específicos, que presenta un curso benigno. Entre las modalidades de imágenes para el diagnóstico se encuentran métodos convencionales, como el ultrasonido, la tomografía axial computarizada y la medicina nuclear, que son técnicas útiles para determinar tejido esplénico residual. En el artículo se presenta el caso de un hombre joven con antecedente de trauma esplénico, al cual se le diagnostica esplenosis torácica como parte del estudio de síndrome febril prolongado y síntomas respiratorios.
