ABSTRACT
Fifteen patients with aortic aneurysms have been evaluated with Doppler color flow imaging. Two distinct flow patterns are noted: a smooth laminar pattern and a turbulent circuitous pattern. It is postulated that those patients with a turbulent pattern may be at greater risk for aneurysm enlargement and rupture.
Subject(s)
Aortic Aneurysm/diagnostic imaging , Aorta, Abdominal/diagnostic imaging , Aorta, Abdominal/physiopathology , Aortic Rupture/diagnosis , Blood Flow Velocity , Humans , Regional Blood Flow , Ultrasonography/methodsABSTRACT
Perennial rhinitis with an allergic component (PRAC) in association with chronic mouthbreathing has been thought to cause skeletal open-bite facial type and narrow transverse facial dimensions. The object of this study was to supply data for this theory and to determine if allergy management would alter the course of facial growth. When a group of children, aged 5 to 10 years, with PRAC was compared with a matched control sample, a significantly larger palatomandibular angle and lower anterior facial height were found for the PRAC group. Transverse cephalometric measurements showed significantly narrower bilateral orbital breadth, bizygomatic, and binasal dimensions (narrower face) of the PRAC patients compared with the control sample. A pilot study of twelve PRAC patients who received 2 1/2 years of allergy management revealed no significant dento-facial dimensional change. This study suggests that PRAC with chronic mouthbreathing can alter the development of the midface. Whether allergy therapy can prevent or change this is as yet uncertain.
Subject(s)
Maxillofacial Development , Rhinitis, Allergic, Perennial/complications , Cephalometry , Child , Child, Preschool , Female , Humans , Longitudinal Studies , Male , Mouth Breathing/etiology , Pilot Projects , Rhinitis, Allergic, Perennial/therapy , Time FactorsABSTRACT
We treated 31 patients with ragweed conjunctivitis in an eight-week, double-masked parallel-group study with cromolyn sodium 4% ophthalmic solution. Analysis of data showed preseason serum IgE antibody to ragweed level was a significant predictor of drug response. Of 16 patients with ragweed IgE values of less than 100 ng/ml, the nine treated with cromolyn had significantly fewer symptoms during the course of treatment than the seven in the placebo group. Of the 15 remaining patients, who had IgE levels of more than 100 ng/ml, the eight treated with cromolyn improved but the difference between their symptom scores and those of the seven patients treated with placebo was not statistically significant.
Subject(s)
Conjunctivitis/drug therapy , Cromolyn Sodium/therapeutic use , Hypersensitivity/drug therapy , Adolescent , Adult , Antibodies/analysis , Conjunctivitis/immunology , Double-Blind Method , Female , Humans , Immunoglobulin E/analysis , Male , Middle Aged , PollenABSTRACT
Specific reaginic (IgE) and hemagglutinating (IgG) antibodies were quantified after immunization with ovalbumin aluminum hydroxide gel in BN and ACI inbred rats, as well as their F1, F1 X BN backcross, F2, and F3, and F3 progeny. The dissimilarity of these immune responses indicated that reaginic (IgE) antibody synthesis was influenced by polygenic factors, but not sex, and was controlled by loci different from that governing hemagglutinating (IgG) antibody synthesis. In addition, tissue typing of the BN, ACI, F1, and F3 hybrids suggested that reaginic antibody synthesis was not linked to the major rat histocompatibility locus.
