Subject(s)
Adenocarcinoma/surgery , Stomach Neoplasms/surgery , Adult , Aged , Female , Gastrectomy/methods , Humans , Male , Middle AgedSubject(s)
Celiac Artery , Ischemia/etiology , Adult , Constriction, Pathologic , Female , Humans , Ischemia/diagnosis , Male , Middle Aged , SyndromeABSTRACT
After a brief physiopathological introduction, the results obtained with Cimetidine in 171 cases of peptic oesophagitis are described. Given the high percentage of successes even in serious oesophagitis and the minimal incidence of side effects, cimetidine is the therapy of choice in conservative treatment of peptic oesophagitis.
Subject(s)
Cimetidine/therapeutic use , Esophagitis, Peptic/drug therapy , Guanidines/therapeutic use , Adolescent , Adult , Aged , Drug Evaluation , Esophageal Stenosis/drug therapy , Esophagitis, Peptic/classification , Female , Humans , Male , Middle Aged , Time FactorsABSTRACT
A double blind test with cimetidine and ranitidine conducted on 60 patients with acid reflux oesophagitis revealed cimetidine to be the more effective. Its success is felt to lie more in the drug's ability to activate defensive factors than in its inhibition of acid secretion.
Subject(s)
Anti-Ulcer Agents/therapeutic use , Cimetidine/therapeutic use , Esophagitis, Peptic/drug therapy , Furans/therapeutic use , Guanidines/therapeutic use , Histamine H2 Antagonists/therapeutic use , Adult , Aged , Drug Evaluation , Esophagitis, Peptic/classification , Female , Humans , Male , Middle Aged , Ranitidine , Time FactorsABSTRACT
The short and medium term results obtained with ranitidine on 33 duodenal ulcer patients are reported. The results obtained indicate that ranitidine is excellent for initial therapy but there are doubts about its efficacity in the prophylaxis of recurring ulceration during maintenance treatment. In addition, about 9% of the patients suffered side effects to the extent that treatment had to be interrupted.