[THE ROLE OF PAPILLOMAVIRUS INFECTION IN THE DEVELOPMENT OF BACKGROUND DISEASE OF THE CERVIX].

Papillomavirus infection is one of the most common sexually transmitted infections. The aim of the study was to study the etiologic significance of the papillomavirus infection in the development of background diseases of the cervix and neoplasia. Under observation were 62 patients aged 18 to 55 years infected with human papillomavirus. All patients underwent complex clinical and anamnestic, laboratory and instrumental examination. Also, a review and advanced colposcopy was performed. As a result of the study, 53 (85.4%) women under observation were found to have various pathologies of the cervix. Dysplasia of mild degree (CIN 1 degree) was found in 12 (57.1%), moderate dysplasia (CIN 2 degree) - in 9 (42.9%) women. With further examination, it was found that patients along with dysplasia of varying severity had concomitant pathology of the cervix uteri. Cervical dysplasia was most often diagnosed in combination with another pathology of the cervix, which accounted for 85.7% of cases. It has been established that squamous epithelial lesion of the cervix is most often a consequence of late diagnosis and an untreated background process. At the same time, modern diagnostics requires a whole range of diagnostic measures to establish a diagnosis in the early stages of development and conduct differential diagnosis of a benign or malignant process.

[Differential diagnostics of ovarial neoplasms and hydatids of pelvic localization in girls].

An analysis of differential diagnostics and results of treatment of hydatids in pelvis is described. For 36 year exploration and operations were fulfilled in 465 patients with hydatids of different localization, in 6 (1.3%) of them there was pelvic localization. Cystic formations of the ovaries were found in 211 girls, in 5 (2.4%) it was pelvic localization of hydatids. In 2 cases an isolated lesion of the small pelvis organs was noted, in 4 patients small pelvis hydatids were combined with lesions of other organs. The authors propose a scheme of differential diagnostics with neoplasms of the ovaries. All the patients underwent organ-saving operations. There were no relapses.

[ICIQ-SF questionnaire in women with urinary incontinence].

The ICIQ-SF questionnaire is used for evaluation of clinical manifestations in patients with urinary incontinence (UI) alone and combination of UI with lower urinary tract symptoms as well as assessment of quality of life in females with UI. Our study with ICIQ-SF questionnaire showed that UI was present in 23.8% responders. UI once a week or less often was marked most frequently by 11.6% women from all the age groups. Any volume of UI was marked by 24.5% women, most frequent volumes of urine loss were 15.9% and 7.1% in all age groups. Stress UI was prevalent in all the age groups (52.6%), the rate of urgent UI declined with age of women (16.3%), mixed UI rate, on the contrary, increased with age (26.7%). Significant frequency and volume of urine loss have the highest influence on quality of everyday women's life. Mixed UI reduced quality of life more significantly than stress and urgent UI. Thus, in view of high prevalence of UI among women, low compliance of the patients, the ICIQ-SF questionnaire can be recommended to therapists, gynecologists and urologists of the outpatient clinics for detection of UI in women. Response to ICIQ-SF questionnaire is a simple, easy-to-make and cheap method of preliminary UI diagnosis and assessment of UI impact on quality of life.

[Solifenacin in the treatment of overactive bladder: results of a randomized double-blind, placebo-controlled study].

The article presents the results of the evaluation of clinical efficacy and safety of the M-cholinoblocker solifenacin in the treatment of symptoms of overactive bladder (OAB). The study included 24 women aged from 47 to 69 years with symptoms of OAB lasting more than 3 months. It is shown that solifenacin at a dose of 5 mg reduces the quality of urinary urgency, improves the condition according to assessment of degree of discomfort due to symptoms of the OAB, treatment satisfaction and condition of the bladder.