[Lyme disease with hepatitis and corticosteroids: a case report]. / Maladie de Lyme avec hépatite et corticothérapie: à propos d'une observation.

INTRODUCTION: Abnormalities of liver function tests have been occasionally described in large series of Lyme disease, but only one case of hepatitis directly related to infection have been described in literature. CASE REPORT: A 78-year-old-man, with a past medical history of polymyalgia rheumatica (PMR) who had discontinued corticosteroids two years before, presented a transient acute fever and liver cholestasis and cytolysis after an exposure to tick bites. A few days later, cervical pain occurred and corticosteroids were resumed as a PMR relapse was suspected. Hematogenous dissemination with acute meningoradiculitis and multiple erythema migrans led to conclude to a stage 2 Lyme disease. CONCLUSION: Although hepatitis complicating the course of Lyme disease has been described in literature, the marked inflammation in our patient led us to investigate the possibility of a co-infection. Also, we discuss the responsibility of corticosteroids in clinical worsening of Lyme disease if they are prescribed without concomitant antibiotics.

Contact allergy to safety shoes.

During 1972-1984, 13 cases of allergy to safety shoes were found. It generally affects young men. The allergens are very different from those in other types of shoe. The presence of mercaptobenzothiazole and dibenzothiazyl disulfide detected in some nonwoven materials is worthy of note.

Thin-layer chromatography search for Disperse Yellow 3 and Disperse Orange 3 in 52 stockings and pantyhose.

Thin-layer (uni-dimensional and bi-dimensional) chromatography studies were performed on 52 beige stockings and pantyhose from different countries. They demonstrated the presence of Disperse Yellow 3 in 51 and Disperse Orange 3 in 15 stockings. In the absence of isolation and spectroscopic identification of the dyes, these results are strong clues to their presence.