ABSTRACT
PURPOSE: To report clinical manifestations of ocular allergy to atropine eye drops used for retardation of progressive myopia in children. METHODS: Myopic children, who developed bothersome itching that subsided promptly after cessation of atropine eye drops, were included. History of systemic or ocular allergy, preexisting ocular conditions, and clinical features of allergy were noted. RESULTS: Six children, age 5-15 years, were included. Four developed allergy to 1% atropine sulfate eye drops and two to 0.01% concentration of atropine sulfate. The onset of allergy was within a month to as late as 4 years after using atropine eye drops. The severity of allergy was higher with 1% concentration. The most common symptoms of atropine allergy were itching and burning. The most common signs were lid swelling and hyperemia. The allergic manifestations promptly reversed with the stoppage of eye drops. Reintroduction was possible in three patients, either by reducing the concentration of atropine or using benzalkonium free formulation. CONCLUSION: Allergy to atropine eye drops in children may develop within a few weeks or after many years of usage. Prompt cessation followed by a reintroduction and continuation of therapy may be possible in few patients.
Subject(s)
Atropine/adverse effects , Dermatitis, Allergic Contact/diagnosis , Drug Hypersensitivity/diagnosis , Myopia, Degenerative/drug therapy , Adolescent , Atropine/administration & dosage , Child , Child, Preschool , Dermatitis, Allergic Contact/etiology , Drug Hypersensitivity/complications , Female , Humans , Male , Mydriatics/administration & dosage , Mydriatics/adverse effects , Myopia, Degenerative/physiopathology , Ophthalmic SolutionsABSTRACT
We report a case of penile carcinoma presenting as an inguinal bubo in a young man. The associated painful genital ulcer and history of high-risk sexual behaviour raised a strong suspicion of a sexually transmitted infection. We review the literature for similar cases, highlight the similarities with venereal disease and discuss the differential diagnosis of inguinal bubo.
