[Salmonella infections in Kinshasa: the species involved and sensitivity to antibiotics]. / Les infections à Salmonella à Kinshasa: espèces en cause et sensibilité aux antibiotiques.

292 Salmonella strains were isolated between 1986-1988 in the bacteriological unit of the Cliniques Universitaires de Kinshasa (Zaïre). One hundred of these strains were isolated from pediatric samples. The most frequent strains were S typhi, S enteritidis and S typhimurium. S typhi strains were sensitive to all antibiotics tested. The other salmonella serotypes had an increasing resistance to several antibiotics especially ampicillin, streptomycin, tetracyclin and kanamycin. A significant decline was observed with chloramphenicol and sulfamethoxazol-trimetoprim. Stool-isolated strains from children were found to be resistant to all antibiotics in common use in 5/6 cases. In systemic Salmonella infection, treatment with chloramphenicol or sulfamethoxazole-trimetoprim plus gentamycin is probably preferable to any other antibiotic recommended for Salmonella infection.

Clinical isolates of Cryptococcus neoformans from Zaire.

PIP: The incidence of disseminated cryptococcosis among Central Africans with acquired immunodeficiency syndrome (AIDS) may exceed 35%. Of the 2 varieties of Cryptococcus neoformans--neoformans and gattii--it appears that the neoformans variant is the one most frequently associated with AIDS. This assumption is based on the investigation of 47 cryptococcosis isolates into white mice to determine their ability (variety gattii) or inability (variety neoformans) to produce the elongated cells characteristic of the former variety. Of the 7 isolates collected in 1951-1969, 6 were of the gattii biovar. On the other hand, all of the 40 isolates collected after 1969 were of the biovar neoformans, suggesting that the biovar gattii is disappearing from Central Africa.^ieng