1.
Int J STD AIDS
; 27(11): 1019-22, 2016 10.
Article
in English
| MEDLINE
| ID: mdl-26468273
ABSTRACT
A patient with a delayed diagnosis of vertically transmitted HIV presented with a rare form of severe warm and cold (mixed) autoimmune haemolytic anaemia, six months after starting antiretroviral therapy. The CD4 count had responded rapidly to introduction of antiretroviral therapy, rising from 5 cells/µL to 93 cells/µL over the course of six months. The haemolysis was resistant to immunoglobulin therapy, eventually responding to corticosteroids. On careful scrutiny of the case, we found the features to be in keeping with immune reconstitution inflammatory syndrome; thorough investigations revealed no other trigger for haemolysis in this case.
Subject(s)
AIDS-Related Opportunistic Infections/complications , Anemia, Hemolytic, Autoimmune/immunology , Antiretroviral Therapy, Highly Active , Autoantibodies/blood , HIV Infections/complications , AIDS-Related Opportunistic Infections/drug therapy , Adolescent , Anemia, Hemolytic, Autoimmune/complications , Antitubercular Agents/therapeutic use , CD4 Lymphocyte Count , Delayed Diagnosis , HIV Infections/immunology , Humans , Immune Reconstitution Inflammatory Syndrome/immunology , Infectious Disease Transmission, Vertical , Treatment Outcome , Tuberculosis/diagnosis , Tuberculosis/drug therapy
2.
Haemophilia
; 21(6): e510-3, 2015 Nov.
Article
in English
| MEDLINE
| ID: mdl-26226975