NIRS-Derived Muscle-Deoxygenation and Microvascular Reactivity During Occlusion-Reperfusion at Rest Are Associated With Whole-Body Aerobic Fitness.

Purpose: Near-infrared spectroscopy (NIRS) indices during arterial occlusion-reperfusion maneuver have been used to examine the muscle's oxidative metabolism and microvascular function-important determinants of whole-body aerobic-fitness. The association of NIRS-derived parameters with whole-body VO2max was previously examined using a method requiring exercise (or electrical stimulation) followed by multiple arterial occlusions. We examined whether NIRS-derived indices of muscle deoxygenation and microvascular reactivity assessed during a single occlusion-reperfusion at rest are (a) associated with maximal/submaximal indices of whole-body aerobic-fitness and (b) could discriminate individuals with different VO2max. We, also, investigated which NIRS-parameter during occlusion-reperfusion correlates best with whole-body aerobic-fitness. Methods: Twenty-five young individuals performed an arterial occlusion-reperfusion at rest. Changes in oxygenated- and deoxygenated-hemoglobin (O2Hb and HHb, respectively) in vastus-lateralis were monitored; adipose tissue thickness (ATT) at NIRS-application was assessed. Participants also underwent a maximal incremental exercise test for VO2max, maximal aerobic velocity (MAV), and ventilatory-thresholds (VTs) assessments. Results: The HHbslope and HHbmagnitude of increase (occlusion-phase) and O2Hbmagnitude of increase (reperfusion-phase) were strongly correlated with VO2max (r = .695-.763, p < .001) and moderately with MAV (r = .468-.530; p < .05). O2Hbmagnitude was moderately correlated with VTs (r = .399-.414; p < .05). After controlling for ATT, the correlations remained significant for VO2max (r = .672-.704; p < .001) and MAV (r = .407; p < .05). Individuals in the high percentiles after median and tritile splits for HHbslope and O2Hbmagnitude had significantly greater VO2max vs. those in low percentiles (p < .01-.05). The HHbslope during occlusion was the best predictor of VO2max. Conclusion: NIRS-derived muscle deoxygenation/reoxygenation indices during a single arterial occlusion-reperfusion maneuver are strongly associated with whole-body maximal indices of aerobic-fitness (VO2max, MAV) and may discriminate individuals with different VO2max.

Aerobic adaptations following two iso-effort training programs: an intense continuous and a high-intensity interval.

The intensity of the training stimulus and the effort exerted (regarded as an index of internal load) to complete an exercise session are driving forces for physiological processes and long-term training adaptations. This study compared the aerobic adaptations following two iso-effort, ratings of perceived exertion (RPE)-based training programs, an intense continuous (CON) and a high-intensity interval (INT). Young adults were assigned to a CON (n = 11) or an INT (n = 13) training group to perform 14 training sessions within 6 weeks. The INT group performed running bouts (9.3 ± 4.4 repetitions) at 90% of peak treadmill velocity (PTV) with bout duration equal to 1/4 of time to exhaustion at this speed (134.2 ± 27.9 s). The CONT group ran (1185.0 ± 487.6 s) at a speed corresponding to -2.5% of critical velocity (CV; 80.1% ± 3.0% of PTV). Training-sessions were executed until RPE attained 17 on the Borg scale. VO2max, PTV, CV, lactate threshold velocity (vLT), and running economy were assessed pre-, mid-, and post-training. Both CONT and INT methods increased (p < 0.05) VO2max (INT: 57.7 ± 8.1-61.41 ± 9.2; CONT: 58.1 ± 7.5-61.1 ± 6.3 mL kg-1 min-1), PTV (INT: 14.6 ± 1.8-15.7 ± 2.1; CONT: 15.0 ± 1.7-15.7 ± 1.8 km h-1), CV (INT: 11.8 ± 1.4-12.8 ± 1.8; CONT: 12.2 ± 1.6-12.9 ± 1.7 km h-1), and vLT (INT: 9.77 ± 1.1-10.8 ± 1.4; CONT: 10.4 ± 1.4-11.0 ± 1.8 km h-1) with no differences (p > 0.05) between them; running economy remained unchanged. The continuous training method, when matched for effort and executed at relatively high intensity at the upper boundaries of the heavy-intensity domain (∼80% of PTV), confers comparable aerobic adaptations to those attained after a high-intensity interval protocol following a short-term training period.

Effects of Work and Recovery Duration and Their Ratio on Cardiorespiratory and Metabolic Responses During Aerobic Interval Exercise.

ABSTRACT: Myrkos, A, Smilios, I, Zafeiridis, A, Iliopoulos, S, Kokkinou, EM, Douda, H, and Tokmakidis, SP. Effects of work and recovery duration and their ratio on cardiorespiratory and metabolic responses during aerobic interval exercise. J Strength Cond Res 36(8): 2169-2175, 2022-This study examined the effect of work and recovery durations and of work-to-rest ratio (WRR) on total exercise time and oxygen consumption (V̇ o2 max), on exercise time above 80, 90, and 95% of V̇ o2 max and HRmax, and on blood lactate concentrations during aerobic interval exercise. Twelve men (22.1 ± 1 year) executed, until exhaustion, 4 interval protocols at an intensity corresponding to 100% of maximal aerobic velocity. Two protocols were performed with work bout duration of 120 seconds and recovery durations of 120 (WRR: 1:1) or 60 seconds (WRR: 2:1), and 2 protocols with work bout duration of 60 seconds and recovery durations of 60 (WRR: 1:1) or 30 seconds (WRR: 2:1). When compared at equal exercise time, total V̇ o2 and exercise time at V̇ o2 above 80, 90, and 95% of V̇ o2 max were longer ( p < 0.05) in 120:120, 120:60 and 60:30 vs. the 60:60 protocol. When analyzed for total exercise time (until exhaustion), total V̇ o2 was higher ( p < 0.01) in the 60:60 compared with all other protocols, and in the 120:120 compared with 120:60. Exercise time >95% of V̇ o2 max and HRmax was higher ( p < 0.05) in the 120:120 vs. the 60:60 protocol; there were no differences among protocols for exercise time >90% of V̇ o2 max and HRmax. Blood lactate was lower ( p < 0.05) in the 60:60 compared with all other protocols and in the 60:30 vs. the 120:60. In conclusion, when interval exercise protocols are executed at similar effort (until exhaustion), work and recovery durations do not, in general, affect exercise time at high oxygen consumption and HR rates. However, as work duration decreases, a higher work-to-recovery ratio (e.g., 2:1) should be used to achieve and maintain high (>95% of maximum) cardiorespiratory stimulus. Longer work bouts and higher work-to-recovery ratio seem to activate anaerobic glycolysis to a greater extent, as suggested by greater blood lactate concentrations.

Physiological and Race Pace Characteristics of Medium and Low-Level Athens Marathon Runners.

This study examined physiological and race pace characteristics of medium- (finish time < 240 min) and low-level (finish time > 240 min) recreational runners who participated in a challenging marathon route with rolling hills, the Athens Authentic Marathon. Fifteen athletes (age: 42 ± 7 years) performed an incremental test, three to nine days before the 2018 Athens Marathon, to determine maximal oxygen uptake (VO2 max), maximal aerobic velocity (MAV), energy cost of running (ECr) and lactate threshold velocity (vLTh), and were analyzed for their pacing during the race. Moderate- (n = 8) compared with low-level (n = 7) runners had higher (p < 0.05) VO2 max (55.6 ± 3.6 vs. 48.9 ± 4.8 mL·kg-1·min-1), MAV (16.5 ± 0.7 vs. 14.4 ± 1.2 km·h-1) and vLTh (11.6 ± 0.8 vs. 9.2 ± 0.7 km·h-1) and lower ECr at 10 km/h (1.137 ± 0.096 vs. 1.232 ± 0.068 kcal·kg-1·km-1). Medium-level runners ran the marathon at a higher percentage of vLTh (105.1 ± 4.7 vs. 93.8 ± 6.2%) and VO2 max (79.7 ± 7.7 vs. 68.8 ± 5.7%). Low-level runners ran at a lower percentage (p < 0.05) of their vLTh in the 21.1-30 km (total ascent/decent: 122 m/5 m) and the 30-42.195 km (total ascent/decent: 32 m/155 m) splits. Moderate-level runners are less affected in their pacing than low-level runners during a marathon route with rolling hills. This could be due to superior physiological characteristics such as VO2 max, ECr, vLTh and fractional utilization of VO2 max. A marathon race pace strategy should be selected individually according to each athlete's level.

The Effects of Recovery Duration During High-Intensity Interval Exercise on Time Spent at High Rates of Oxygen Consumption, Oxygen Kinetics, and Blood Lactate.

Smilios, I, Myrkos, A, Zafeiridis, A, Toubekis, A, Spassis, A, and Tokmakidis, SP. The effects of recovery duration during high-intensity interval exercise on time spent at high rates of oxygen consumption, oxygen kinetics, and blood lactate. J Strength Cond Res 32(8): 2183-2189, 2018-The recovery duration and the work-to-recovery ratio are important aspects to consider when designing a high-intensity aerobic interval exercise (HIIE). This study examined the effects of recovery duration on total exercise time performed above 80, 90, and 95% of maximum oxygen consumption (V[Combining Dot Above]O2max) and heart rate (HRmax) during a single-bout HIIE. We also evaluated the effects on V[Combining Dot Above]O2 and HR kinetics, blood lactate concentration, and rating of perceived exertion (RPE). Eleven moderately trained men (22.1 ± 1 year) executed, on 3 separate sessions, 4 × 4-minute runs at 90% of maximal aerobic velocity (MAV) with 2, 3, and 4 minutes of active recovery. Recovery duration did not affect the percentage of V[Combining Dot Above]O2max attained and the total exercise time above 80, 90, and 95% of V[Combining Dot Above]O2max. Exercise time above 80 and 90% of HRmax was longer with 2 and 3 minutes (p ≤ 0.05) as compared with the 4-minute recovery. Oxygen uptake and HR amplitude were lower, mean response time slower (p ≤ 0.05), and blood lactate and RPE higher with 2 minutes compared with 4-minute recovery (p ≤ 0.05). In conclusion, aerobic metabolism attains its upper functional limits with either 2, or 3 or 4 minutes of recovery during the 4 × 4-minute HIIE; thus, all rest durations could be used for the enhancement of aerobic capacity in sports, fitness, and clinical settings. The short (2 minutes) compared with longer (4 minutes) recovery, however, evokes greater cardiovascular and metabolic stress and activates to a greater extent anaerobic glycolysis and hence, could be used by athletes to induce greater overall physiological challenge.