ABSTRACT
Patients with chronic hepatitis were found to develop an inadequate di- and natriuretic responses to osmotic agents administered into the gastrointestinal tract. In liver cirrhosis, the intensity of adaptive responses decreases or they completely disappeared. The causes for these abnormalities are impairment of osmoregulatory reflex links and dyscoordination of humoral factors.
Subject(s)
Liver Diseases/physiopathology , Water-Electrolyte Balance/physiology , Chronic Disease , Homeostasis/physiology , Humans , Ion Transport/physiology , Natriuresis/physiologyABSTRACT
During formation of hepatic cirrhosis in animals, excessive potassium loss has been found to depend on the increased loading of a nephron by its cation at its early stage and on abnormally changed tubular processes at late stages.
Subject(s)
Kidney/metabolism , Liver Cirrhosis, Experimental/metabolism , Potassium/urine , Animals , Dogs , Liver Cirrhosis, Experimental/urineABSTRACT
The article analyses the experience in surgical treatment of patients with ischemic heart disease (504 cases) by indirect revascularization of the myocardium by creating aseptic mediastino-exo-pericarditis. Clinical characteristic of the patients is given, 81.1% of them had a history of myocardial infarction; 57.7% were invalids; the diagnosis was confirmed by coronarography in 56.2%; 92.1% of patients who underwent operation were related to III-IV functional classes. Late-5-year results showed marked improvement of the condition in 47.3%, moderate improvement in 31.6% and absence of an effect in 21.1% of patients. Postoperative lethality was 1.1%.
Subject(s)
Coronary Disease/surgery , Myocardial Revascularization/methods , Adult , Aged , Angiography , Coronary Angiography , Coronary Disease/diagnostic imaging , Follow-Up Studies , Humans , Male , Middle Aged , Time FactorsABSTRACT
The author analyzes the clinical observation of 534 patients with the ulcerous disease of the stomach and duodenum. All the patients were operated upon. The indication for surgery was pyloric stenosis in 28,6%, hemorrhage in 22,3%, perforation in 12%, penetration in 20%, ulcer-carcinoma in 5,5%, combination of complications in 9,9% and others in 1,7% of cases. The principles of surgery upon the stomach and vagal nerves are substantiated.